Mechanically accelerated catalytic hydrogenation: correlating physical state, reaction rate, and interface area

This study thoroughly examines the role of mechanochemistry in organic synthesis by analysing the factors affecting the mechanochemical reduction process of unsaturated and oxidized compounds. Hydride species and hydrogen gas are generated in situ by mixing a diboron compound with a stoichiometric amount of water. The process is tested against several substrates to determine how the physical state of the reagents influences the reduction technique. The study aims to thoroughly investigate the correlation between the mixing process, reaction rate, and interface area.