We have shown that GABA-stimulated chloride influx into membrane vesicles from the rat cerebral cortex can be enhanced or inhibited by β-carbolines. The β-carbolines can produce a full spectrum of responses from maximal enhancement to maximal inhibition.
Modulation of GABA-stimulated chloride influx by beta-carbolines in rat brain membrane vesicles
SERRA, MARIANGELA;
1988-01-01
Abstract
We have shown that GABA-stimulated chloride influx into membrane vesicles from the rat cerebral cortex can be enhanced or inhibited by β-carbolines. The β-carbolines can produce a full spectrum of responses from maximal enhancement to maximal inhibition.
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