State of the art: the treatment of systemic lupus erythematosus

Purpose of reviewSystemic lupus erythematosus (SLE) is a systemic autoimmune disease with dysregulated cells in the immune system. The disease affects organs like kidneys, nervous system, joints, and skin. To manage SLE effectively, novel treatments targeting immune system components have been developed. This review investigates the therapeutic potential of existing targeted therapies and explores future innovative approaches for well tolerated, personalized treatment.Recent findingsSLE treatment involves cytokine targets and specific immunologic pathways, with even small molecules involved.SummaryThe advanced therapeutic options in SLE management give clinicians more tools to control disease activity according to personalized medicine.