In the present study, the bezafibrate levels were measured in serum of rats treated with lead nitrate using a high performance liquid chromatography (HPLC) method. The results have shown that the peak corresponding to bezafibrate in the chromatogram is reduced in serum of rats treated with bezafibrate plus lead, indicating that lead treatment accelerates the metabolism of bezafibrate in rats. (C) 1998 Elsevier Science S.A. All rights reserved.

Determination of bezafibrate concentration by high performance liquid-chromatography in serum of rats treated with lead nitrate

FADDA, ANNA MARIA;
1998

Abstract

In the present study, the bezafibrate levels were measured in serum of rats treated with lead nitrate using a high performance liquid chromatography (HPLC) method. The results have shown that the peak corresponding to bezafibrate in the chromatogram is reduced in serum of rats treated with bezafibrate plus lead, indicating that lead treatment accelerates the metabolism of bezafibrate in rats. (C) 1998 Elsevier Science S.A. All rights reserved.
Bezafibrate metabolism, HPLC determination, Lead nitrate, Liver hyperplasia
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11584/43907
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