A disregulation in angiogenesis is well recognized as one of the critical mechanisms involved in the progression of inflammatory arthritis. Ultrasound (US) and Power Doppler Ultrasound (PDUS) have been proposed as useful techniques to clearly demonstrate inflammation and blood flow in Spondyloarthritis. Given the efficacy of PDUS in visualizing vascularisation, and the relevance of pro-angiogenic mediators in the development of neo-angiogenesis, combining both tools could improve the monitoring of clinical activity and the efficacy of therapy.
Angiogenesis in spondyloarthritis: target for new diagnostic approaches
PUXEDDU, ILARIA;
2012-01-01
Abstract
A disregulation in angiogenesis is well recognized as one of the critical mechanisms involved in the progression of inflammatory arthritis. Ultrasound (US) and Power Doppler Ultrasound (PDUS) have been proposed as useful techniques to clearly demonstrate inflammation and blood flow in Spondyloarthritis. Given the efficacy of PDUS in visualizing vascularisation, and the relevance of pro-angiogenic mediators in the development of neo-angiogenesis, combining both tools could improve the monitoring of clinical activity and the efficacy of therapy.
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