Linear and angular furocoumarins can be obtained starting from phloroglucinol in a versatile, simple, direct, and efficient way, as demonstrated in the divergent syntheses described here. The key step is the alkali-mediated rearrangement of 4-halomethylcoumarins to benzofuran-3-acetic acids via α,β-unsaturated acids and the key intermediates are benzodipyrones, which, depending on their substitution, can either give or fail to give the ring-contraction reaction.

Divergent Synthesis of Linear and Angular Furocoumarin Acetic Acids from Phloroglucinol

DELOGU, GIOVANNA LUCIA;PICCIAU, MARIA CARMEN;
2007-01-01

Abstract

Linear and angular furocoumarins can be obtained starting from phloroglucinol in a versatile, simple, direct, and efficient way, as demonstrated in the divergent syntheses described here. The key step is the alkali-mediated rearrangement of 4-halomethylcoumarins to benzofuran-3-acetic acids via α,β-unsaturated acids and the key intermediates are benzodipyrones, which, depending on their substitution, can either give or fail to give the ring-contraction reaction.
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11584/94455
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? 5
social impact