The outcome of the reaction between 1 2-diaryl-1 2-disodioethanes and halogenated benzoic acids strongly depends on the nature of both reaction partners Indeed whilst chloro- bromo- and iodobenzoic acids are easily dehalogenated the reductive cleavage of fluorobenzoic acids proceeds to a high extent only in the presence of the dianions endowed with more powerful reducing properties Moreover it was observed that ortho-substituted benzoic acids are more easily dehalogenated than the corresponding pare or meta isomers These observations allowed the development of reaction conditions for the exhaustive or regioselective cleavage of selected polyhalogenated benzoic acids (C) 2010 Elsevier Ltd All rights reserved

Active-sodium-promoted reductive cleavage of halogenated benzoic acids

CERIONI, GIOVANNI;MOCCI, FRANCESCA
2010

Abstract

The outcome of the reaction between 1 2-diaryl-1 2-disodioethanes and halogenated benzoic acids strongly depends on the nature of both reaction partners Indeed whilst chloro- bromo- and iodobenzoic acids are easily dehalogenated the reductive cleavage of fluorobenzoic acids proceeds to a high extent only in the presence of the dianions endowed with more powerful reducing properties Moreover it was observed that ortho-substituted benzoic acids are more easily dehalogenated than the corresponding pare or meta isomers These observations allowed the development of reaction conditions for the exhaustive or regioselective cleavage of selected polyhalogenated benzoic acids (C) 2010 Elsevier Ltd All rights reserved
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11584/94601
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 9
  • ???jsp.display-item.citation.isi??? 9
social impact