The in vitro properties of ten flurazepam capsule formulations marketed in Italy were studied. All studied formulations showed a good agreement with pharmacopoeial requirements. In particular all studied capsules showed a quite fast release of the hypnotic drug even if some differences could be observed. Generally, time dissolution varied between 10 and 20 min on varying dissolution medium pH, active ingredient concentrations and excipients employed. (C) 1998 Elsevier Science S.A. All rights reserved.
Dissolution properties of flurazepam capsules
BAROLI, BIANCA MARIA;FADDA, ANNA MARIA;MANCONI, MARIA;SINICO, CHIARA;VALENTI, DONATELLA
1998-01-01
Abstract
The in vitro properties of ten flurazepam capsule formulations marketed in Italy were studied. All studied formulations showed a good agreement with pharmacopoeial requirements. In particular all studied capsules showed a quite fast release of the hypnotic drug even if some differences could be observed. Generally, time dissolution varied between 10 and 20 min on varying dissolution medium pH, active ingredient concentrations and excipients employed. (C) 1998 Elsevier Science S.A. All rights reserved.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.