The biopharmaceutical properties of eight lorazepam tablet formulations, marketed in Italy, were studied and compared. A few significant differences in behaviour were found even among similar formulations. In vitro dissolution patterns vazied on varying pH, technological properties, excipients employed and active ingredient concentrations.
Comparative biopharmaceutical properties of commercial lorazepam tablets
BAROLI, BIANCA MARIA;FADDA, ANNA MARIA;
1996-01-01
Abstract
The biopharmaceutical properties of eight lorazepam tablet formulations, marketed in Italy, were studied and compared. A few significant differences in behaviour were found even among similar formulations. In vitro dissolution patterns vazied on varying pH, technological properties, excipients employed and active ingredient concentrations.
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