Enaminonitriles 1 react in mild conditions with beta-trifluoroacetylvinyl ethers 2 to give the pyridine derivatives 4. The reaction involves the formation of the intermediate 3, that can be isolated when enol ether 2a is used.
Synthesis of triflouromethylated pyridinecarbonitriles
CONGIU, CENZO;ONNIS, VALENTINA
1995-01-01
Abstract
Enaminonitriles 1 react in mild conditions with beta-trifluoroacetylvinyl ethers 2 to give the pyridine derivatives 4. The reaction involves the formation of the intermediate 3, that can be isolated when enol ether 2a is used.
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