We report on a patient with chronic phase CML who developed hyperbilirubinemia during nilotinib treatment, showing a pattern of UGT1A1 polymorphisms so far undescribed in this clinical setting.

A novel pattern of uridine diphosphate glucuronosyltranferase polymorphisms associated with hyperbilirubinemia during nilotinib treatment

COIANA, ALESSANDRA;ROSATELLI, MARIA CRISTINA;
2013-01-01

Abstract

We report on a patient with chronic phase CML who developed hyperbilirubinemia during nilotinib treatment, showing a pattern of UGT1A1 polymorphisms so far undescribed in this clinical setting.
2013
Adult; Genotype; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Leukemia, myelogenous, chronic, BCR-ABL positive; Male; Polymorphism, genetic; Pyrimidinec
File in questo prodotto:
File Dimensione Formato  
Blood Cells Mol Dis 2013.pdf

Solo gestori archivio

Tipologia: versione editoriale (VoR)
Dimensione 110.87 kB
Formato Adobe PDF
110.87 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11584/100470
Citazioni
  • ???jsp.display-item.citation.pmc??? 0
  • Scopus 2
  • ???jsp.display-item.citation.isi??? 1
social impact