Three novel benzophenones (1–3) were obtained from the roots of Securidaca diversifolia (L.) S.F. Blake along with two known benzylbenzoates and isovanilline. Compound 2 (2,4-dihydroxy-3,30-dimethoxybenzophenone) showedmoderate inhibitory activity on Herpes simplex virus type 1 proliferation in vitro. The structures of compounds 1–3 were established by the interpretation of their spectroscopic and spectrometric data.
Three novel benzophenones (1-3) were obtained from the roots of Securidaca diversifolia (L.) S.F. Blake along with two known benzylbenzoates and isovanilline. Compound 2 (2,4-dihydroxy-3,3′-dimethoxy-benzophenone) showed moderate inhibitory activity on Herpes simplex virus type 1 proliferation in vitro. The structures of compounds 1-3 were established by the interpretation of their spectroscopic and spectrometric data.
Benzophenones from the roots of the Popoluca Amerindian medicinal plant Securidaca diversifolia (L.) S.F. Blake
CASU, LAURA;COTTIGLIA, FILIPPO;CABONI, PIERLUIGI;FLORIS, COSTANTINO;POMPEI, RAFFAELLO;LEONTI, MARCO
2010-01-01
Abstract
Three novel benzophenones (1-3) were obtained from the roots of Securidaca diversifolia (L.) S.F. Blake along with two known benzylbenzoates and isovanilline. Compound 2 (2,4-dihydroxy-3,3′-dimethoxy-benzophenone) showed moderate inhibitory activity on Herpes simplex virus type 1 proliferation in vitro. The structures of compounds 1-3 were established by the interpretation of their spectroscopic and spectrometric data.
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