Patients with thalassemia major suffer from many complications, but in the last two decades their lives have improved both in length and quality. We report herein the most common complications and the recent advances that have changed the course of this disease. Also, we report in detail some of the new therapeutic strategies already introduced in practice and briefly some that are still being developed.

A complicated disease: What can be done to manage thalassemia major more effectively?

ORIGA, RAFFAELLA;
2015

Abstract

Patients with thalassemia major suffer from many complications, but in the last two decades their lives have improved both in length and quality. We report herein the most common complications and the recent advances that have changed the course of this disease. Also, we report in detail some of the new therapeutic strategies already introduced in practice and briefly some that are still being developed.
Bisphosphonates; Gene therapy; HbF reactivation; ron chelation; Iron overload; JAK2; magnetic resonance imaging; Osteoporosis; Sotatercept; Stem cell transplantation
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11584/141140
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