Patients with thalassemia major suffer from many complications, but in the last two decades their lives have improved both in length and quality. We report herein the most common complications and the recent advances that have changed the course of this disease. Also, we report in detail some of the new therapeutic strategies already introduced in practice and briefly some that are still being developed.

A complicated disease: What can be done to manage thalassemia major more effectively?

ORIGA, RAFFAELLA;
2015-01-01

Abstract

Patients with thalassemia major suffer from many complications, but in the last two decades their lives have improved both in length and quality. We report herein the most common complications and the recent advances that have changed the course of this disease. Also, we report in detail some of the new therapeutic strategies already introduced in practice and briefly some that are still being developed.
2015
Bisphosphonates; Gene therapy; HbF reactivation; ron chelation; Iron overload; JAK2; magnetic resonance imaging; Osteoporosis; Sotatercept; Stem cell transplantation
File in questo prodotto:
File Dimensione Formato  
2015 Review con Caterina.pdf

Solo gestori archivio

Tipologia: versione post-print (AAM)
Dimensione 718.47 kB
Formato Adobe PDF
718.47 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11584/141140
Citazioni
  • ???jsp.display-item.citation.pmc??? 1
  • Scopus 9
  • ???jsp.display-item.citation.isi??? 8
social impact