HIV-1 reverse transcriptase-associated ribonuclease H (RNase H) is an attractive non traditional target for drug development which has been, so far, little explored. All drugs shown to inhibit HIV-1 RNase H are reported, including the recently described classes of compounds that interact with the metal ions in the active site.
HIV-1 RNase H: Recent Progress in an Exciting, yet Little Explored, Drug Target
TRAMONTANO, ENZO
2006-01-01
Abstract
HIV-1 reverse transcriptase-associated ribonuclease H (RNase H) is an attractive non traditional target for drug development which has been, so far, little explored. All drugs shown to inhibit HIV-1 RNase H are reported, including the recently described classes of compounds that interact with the metal ions in the active site.
File in questo prodotto:
Non ci sono file associati a questo prodotto.
I metadati presenti in IRIS UNICA sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono protetti da diritto d'autore, salvo diversa indicazione.
