Volatile oils composition from leaves and ripe fruits of pink pepper (Schinus terebinthifolius Raddi) growing in Tunisia were investigated using GC-FID and GC-MS techniques. Volatile oil extraction was achieved by hydrodistillation (HD) using a Clevenger apparatus and by supercritical fluid extraction (SFE) using carbon dioxide. All plant organs, gave SFE extracts chiefly composed by α-pinene, α-phellandrene, β-phellandrene, germacrene D and bicyclogermacrene. In the case of the fruits, both extraction techniques gave volatile oils of similar composition; whereas the comparison between the HD and SFE leave oils revealed important differences in the content of α-pinene (6.1 % vs traces), α-phellandrene (22.7 % vs 0.8 %) and β-phellandrene (14.6 % vs 1.2 %). All volatile samples were evaluated against yeasts and dermatophyte strains, being more active against Cryptococcus neoformans, particularly the volatile oil from the fruits, with MIC values of (0.32-0.64) mg/mL. Moreover, this oil revealed an inhibitory effect on germ tube formation in C. albicans at sub-inhibitory concentration. At the concentration of MIC/8 the inhibition of filamentation was more than 70 %.

Chemical composition and biological activity of volatile extracts from leaves and fruits of Schinus terebinthifolius Raddi from Tunisia

PIRAS, ALESSANDRA;PORCEDDA, SILVIA;
2017

Abstract

Volatile oils composition from leaves and ripe fruits of pink pepper (Schinus terebinthifolius Raddi) growing in Tunisia were investigated using GC-FID and GC-MS techniques. Volatile oil extraction was achieved by hydrodistillation (HD) using a Clevenger apparatus and by supercritical fluid extraction (SFE) using carbon dioxide. All plant organs, gave SFE extracts chiefly composed by α-pinene, α-phellandrene, β-phellandrene, germacrene D and bicyclogermacrene. In the case of the fruits, both extraction techniques gave volatile oils of similar composition; whereas the comparison between the HD and SFE leave oils revealed important differences in the content of α-pinene (6.1 % vs traces), α-phellandrene (22.7 % vs 0.8 %) and β-phellandrene (14.6 % vs 1.2 %). All volatile samples were evaluated against yeasts and dermatophyte strains, being more active against Cryptococcus neoformans, particularly the volatile oil from the fruits, with MIC values of (0.32-0.64) mg/mL. Moreover, this oil revealed an inhibitory effect on germ tube formation in C. albicans at sub-inhibitory concentration. At the concentration of MIC/8 the inhibition of filamentation was more than 70 %.
Antifungal activity; Essential oil; Schinus terebinthifolius; Supercritical carbon dioxide extracts; Pharmacology; Plant science; Drug discovery; Pharmaceutical science; Organic chemistry
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11584/194792
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