The acid-promoted syntheses of 2-(benzyloxy)cyclobutanones and bis(benzyloxy)dioxatricyclo decanes were achieved starting from 2-hydroxycyclobutanone and variously functionalized benzyl alcohols. The reaction sequences afforded the desired products in good to high yields and in a solvent-dependent chemoselective fashion.
Acid-catalyzed reaction of 2-hydroxycyclobutanone with benzylic alcohols
Martis, Alberto;Luridiana, Alberto;Frongia, Angelo;Arca, Massimiliano;Sarais, Giorgia;Secci, Francesco
2017-01-01
Abstract
The acid-promoted syntheses of 2-(benzyloxy)cyclobutanones and bis(benzyloxy)dioxatricyclo decanes were achieved starting from 2-hydroxycyclobutanone and variously functionalized benzyl alcohols. The reaction sequences afforded the desired products in good to high yields and in a solvent-dependent chemoselective fashion.
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