A unified protocol for the construction of 3-(2-bromoethyl)benzofurans and 2-(benzofuran-3-yl)ethylamines from bis[(trimethylsilyl)oxy]cyclobutene has been developed. This mild and facile strategy was applied for the synthesis of a series of 5-HT serotonin receptor agonists, underlining its potential for the syntheses of bioactive compounds and natural products.
Brønsted Acid Mediated Cascade Reaction to Access 3-(2-Bromoethyl)benzofurans
Porcu, StefaniaPrimo
;DEMURO, STEFANIA;Luridiana, Alberto;Frongia, Angelo;Sarais, Giorgia;Secci, Francesco
Ultimo
2018-01-01
Abstract
A unified protocol for the construction of 3-(2-bromoethyl)benzofurans and 2-(benzofuran-3-yl)ethylamines from bis[(trimethylsilyl)oxy]cyclobutene has been developed. This mild and facile strategy was applied for the synthesis of a series of 5-HT serotonin receptor agonists, underlining its potential for the syntheses of bioactive compounds and natural products.
File in questo prodotto:
| File | Dimensione | Formato | |
|---|---|---|---|
|
Brønsted Acid Mediated Cascade Reaction to Access 3-(2-Bromoethyl)benzofurans.pdf
Solo gestori archivio
Tipologia:
versione editoriale (VoR)
Dimensione
1.06 MB
Formato
Adobe PDF
|
1.06 MB | Adobe PDF | Visualizza/Apri Richiedi una copia |
I metadati presenti in IRIS UNICA sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono protetti da diritto d'autore, salvo diversa indicazione.
