A convenient synthesis of 4-amino-7-(dialkylamino)pyrido[2,3-d]pyrimidines via cyclization of functionalized pyridines is reported. The preparation of the starting pyridines from 3-amino-3-(dialkylaraino)propene-nitriles and ethoxymethylenemalononitrile is described.
Cocco, M.T., Congiu, C., Maccioni, A., Onnis, V Convenient synthesis of 4-amino-7-(dialkylamino)pyrido[2,3-d]pyrimidines from polysubstituted pyridines
CONGIU, CENZO;ONNIS, VALENTINA
1993-01-01
Abstract
A convenient synthesis of 4-amino-7-(dialkylamino)pyrido[2,3-d]pyrimidines via cyclization of functionalized pyridines is reported. The preparation of the starting pyridines from 3-amino-3-(dialkylaraino)propene-nitriles and ethoxymethylenemalononitrile is described.
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