This work studies the existence of classical solutions to a class of chemotaxis systems by [formula] that model interactions between tumor (i.e., w) and immune cells (i.e., u) with a logistic-type source term [formula], also in presence of a chemical signal (i.e., v). The model parameters [formula], and are all positive. The vector v is the outward unit normal on delta-omega. The value [formula] indicates the maximum instant of time up to which solutions are defined. Our focus is on examining the global existence in a bounded domain [formula], under Neumann boundary conditions. We distinguish between two scenarios: [formula] and [formula]. The first case allows to prove boundedness under smaller assumptions relying only on the model parameters instead of on the initial data, while the second case requires an extra condition relating the parameters [formula], and the initial data [formula]. This model can be seen as an extension of those previously examined in [11] and [4], the former being a system with only two equations and the latter the same model without logistic.

Tumor-immune cell interactions by a fully parabolic chemotaxis model with logistic source

Diaz Fuentes, Rafael
2026-01-01

Abstract

This work studies the existence of classical solutions to a class of chemotaxis systems by [formula] that model interactions between tumor (i.e., w) and immune cells (i.e., u) with a logistic-type source term [formula], also in presence of a chemical signal (i.e., v). The model parameters [formula], and are all positive. The vector v is the outward unit normal on delta-omega. The value [formula] indicates the maximum instant of time up to which solutions are defined. Our focus is on examining the global existence in a bounded domain [formula], under Neumann boundary conditions. We distinguish between two scenarios: [formula] and [formula]. The first case allows to prove boundedness under smaller assumptions relying only on the model parameters instead of on the initial data, while the second case requires an extra condition relating the parameters [formula], and the initial data [formula]. This model can be seen as an extension of those previously examined in [11] and [4], the former being a system with only two equations and the latter the same model without logistic.
2026
Chemotaxis systems; classical solutions; global existence; boundedness; tumor-immune cell interaction
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11584/462347
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