UNICA IRIS Institutional Research Information System

RUGGERONE, PAOLO
 Distribuzione geografica
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Continente #
EU - Europa 219.439
NA - Nord America 9.536
AS - Asia 1.314
Continente sconosciuto - Info sul continente non disponibili 12
OC - Oceania 8
AF - Africa 4
SA - Sud America 3
Totale 230.316
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Nazione #
IT - Italia 216.928
US - Stati Uniti d'America 9.392
CN - Cina 891
UA - Ucraina 832
SE - Svezia 551
GB - Regno Unito 418
DE - Germania 327
FI - Finlandia 235
SG - Singapore 210
CA - Canada 142
FR - Francia 69
VN - Vietnam 68
IN - India 61
TW - Taiwan 27
KR - Corea 20
BE - Belgio 17
NL - Olanda 15
EU - Europa 12
RU - Federazione Russa 12
IR - Iran 8
AT - Austria 7
AU - Australia 7
CH - Svizzera 7
HK - Hong Kong 7
JP - Giappone 6
ES - Italia 5
TR - Turchia 5
IE - Irlanda 3
PH - Filippine 3
BG - Bulgaria 2
CZ - Repubblica Ceca 2
LU - Lussemburgo 2
MU - Mauritius 2
NG - Nigeria 2
TH - Thailandia 2
BR - Brasile 1
CO - Colombia 1
CY - Cipro 1
GT - Guatemala 1
HR - Croazia 1
HU - Ungheria 1
ID - Indonesia 1
IL - Israele 1
IQ - Iraq 1
IS - Islanda 1
JO - Giordania 1
LB - Libano 1
LT - Lituania 1
MX - Messico 1
NZ - Nuova Zelanda 1
PL - Polonia 1
PT - Portogallo 1
PY - Paraguay 1
RO - Romania 1
Totale 230.316
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Città #
Cagliari 208.697
Uta 7.583
Fairfield 1.313
Woodbridge 984
Ashburn 714
Chandler 664
Houston 643
Seattle 559
Boardman 553
Ann Arbor 542
Wilmington 518
Jacksonville 467
Cambridge 454
Nyköping 361
Dearborn 327
Nanjing 168
Munich 136
Boston 125
Mcallen 120
Beijing 109
Montréal 109
Helsinki 107
Singapore 91
Shanghai 79
New York 69
Dong Ket 66
Milan 63
Redwood City 63
San Diego 62
Nanchang 48
Shenyang 48
Guangzhou 46
Hebei 45
Changsha 39
Jiaxing 38
Los Angeles 35
Fonni 31
Mountain View 31
London 30
Hefei 28
Falls Church 27
Verona 27
New Taipei 26
Sassari 26
Tianjin 26
Washington 26
Zhengzhou 24
Cedar Knolls 22
Orange 22
Jinan 20
Norwalk 20
Rome 19
Toronto 19
Phoenix 17
Seoul 17
Kunming 16
Brussels 15
Chicago 15
Ningbo 15
Norman 14
Marseille 13
Pune 13
Taizhou 12
Ottawa 11
Wuhan 11
Redmond 9
Auburn Hills 8
Hangzhou 8
Quartu Sant'elena 8
Fuzhou 7
Kilburn 7
Stockholm 7
Indiana 6
Napoli 6
Saint Petersburg 6
Walnut 6
Bologna 5
Hounslow 5
Liverpool 5
Tonara 5
Vienna 5
Yiwu 5
Carbonia 4
Dallas 4
Edinburgh 4
Jinhua 4
Patna 4
San Francisco 4
Sinnai 4
Zurich 4
Alameda 3
Amsterdam 3
Borås 3
Brisbane 3
Casamicciola Terme 3
Chengdu 3
Chennai 3
Chiswick 3
Council Bluffs 3
Dublin 3
Totale 226.808
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Nome #
Different molecular mechanisms of inhibition of bovine viral diarrhea virus and hepatitis C virus RNA-dependent RNA polymerases by a novel benzimidazole 36.726
Structure-Activity Relationship Study of Hydroxycoumarins and Mushroom Tyrosinase 4.541
A database of force-field parameters, dynamics, and properties of antimicrobial compounds 3.872
Multidrug efflux pumps and their inhibitors characterized by computational modeling 3.831
Insights into the homo-oligomerization properties of N-terminal coiled-coil domain of Ebola virus VP35 protein 3.122
Molecular basis for the different interactions of congeneric substrates with the polyspecific transporter AcrB 2.939
Water-mediated interactions enable smooth substrate transport in a bacterial efflux pump 2.900
A novel dendrimeric peptide with antimicrobial properties: structure-function analysis of SB056 2.886
Computer simulations of the activity of RND efflux pumps 2.875
Relevance of Ebola virus VP35 homo-dimerization on the type I interferon cascade inhibition 2.857
Molecular Rationale behind the Differential Substrate Specificity of Bacterial RND Multi-Drug Transporters 2.848
Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives 2.839
Molecular Modeling of Multidrug Properties of Resistance Nodulation Division (RND) Transporters 2.783
Computational modelling of efflux pumps and their inhibitors 2.765
Molecular Determinants of the Promiscuity of MexB and MexY Multidrug Transporters of Pseudomonas aeruginosa 2.748
A Novel Dendrimeric Peptide with Antimicrobial Properties: Structure-Function Analysis of SB056 2.737
A New Critical Conformational Determinant of Multidrug Efflux by an MFS Transporter 2.685
Molecular Interactions of Cephalosporins with the Deep Binding Pocket of the RND Transporter AcrB 2.685
Insights into Ebola VP35 oligomerization from molecular simulations 2.651
Molecular dynamics computer simulations of multidrug RND efflux pumps 2.644
Computational study of correlated domain motions in the AcrB efflux transporter 2.584
Structural and functional characterization of a new double variant haemoglobin (HbG-Philadelphia/Duarte α268Asn→Lys β262Ala→Pro) 2.573
AcrB drug-binding pocket substitution confers clinically relevant resistance and altered substrate specificity 2.535
Analysis of fast channel blockage: revealing substrate binding in the microsecond range 2.474
Identification and characterization of carbapenem binding sites within the RND-transporter AcrB 2.468
Molecular mechanism of MBX2319 inhibition of Escherichia coli AcrB multidrug efflux pump and comparison with other inhibitors 2.416
RND efflux pumps: structural information translated into function and inhibition mechanisms 2.275
Folding and Self-Assembly of the Pore-Forming Unit Tat-A of the Bacterial Twin-Arginine Translocase 2.238
Modeling Assembly of the Tata Pore Forming Complex using an Implicit Membrane Model 2.169
Binding and Transport of Carboxylated Drugs by the Multidrug Transporter AcrB 2.096
The challenge of intracellular antibiotic accumulation, a function of fluoroquinolone influx versus bacterial efflux 2.032
A kinetic Monte Carlo approach to investigate antibiotic translocation through bacterial porins 2.016
Folding and self-assembly of the TatA translocation pore based on a charge zipper mechanism 1.995
Mechanism of Inhibition By, and of Drug Resistance to, a Benzimidazole Inhibitor of the RNA-Dependent RNA Polymerase of Bovine Viral Diarrhoea Virus 1.994
Interaction of antibacterial compounds with RND efflux pumps in Pseudomonas aeruginosa 1.905
Molecular Mechanism of Viral Resistance to a Potent Non-nucleoside Inhibitor Unveiled by Molecular Simulations 1.888
Chlorpromazine and amitriptyline are substrates and inhibitors of the acrb multidrug efflux pump 1.848
Pathways to exit a receptor: a dynamical view of agonists - delta-opioids interaction 1.842
Molecular interactions of carbapenem antibiotics with the multidrug efflux transporter acrb of escherichia coli 1.824
Effects of Point Mutations on the Activity of AcrB 1.796
Molecular simulations reveal the mechanism and the determinants for ampicillin translocation through OmpF 1.788
Using Molecular Simulations to Screen for Antibiotics with Enhanced Permeation Properties through Bacterial Pores 1.773
Exploring Binding Properties of Agonists Interacting with a δ-Opioid Receptor 1.738
null 1.683
Heme proteins: the role of solvent on the dynamics of gates and portals 1.655
Point Mutation I261M Affects the Dynamics of BVDV and its Interaction with Benzimidazole Antiviral 227G 1.633
Towards screening for antibiotics with enhanced permeation properties through bacterial porins 1.585
Investigating reaction pathways in rare events simulations of antibiotics diffusion through protein channels 1.582
Structural and dynamical properties of the porins OmpF and OmpC: insights from molecular simulations 1.559
Recognition of imipenem and meropenem by the RND-transporter MexB studied by computer simulations 1.527
Bridging time and length scales: from macroscopic flux to molecular mechanism of antibiotics diffusion through porins 1.501
Cryo-EM structure and molecular dynamics analysis of the fluoroquinolone resistant mutant of the AcrB transporter from salmonella 1.453
Structural Determinants Of Antibiotic And betalactamase Diffusion Through Bacterial Porins 1.445
Mechanism of inhibition by, and drug resistance to, a benzimidazole inhibitor of the Rna-dependent-Rna-polymerase of Bovine Viral Diarrhoea virus 1.360
null 1.359
Perturbed structural dynamics underlie inhibition and altered efflux of the multidrug resistance pump AcrB 1.357
Structural determinants of antibiotic translocations in OMPF 1.356
Advanced computational methods in molecular medicine 1.304
Simulating bacterial efflux: how molecular features affect functional rotation 1.273
Predictive rules of efflux inhibition and avoidance in Pseudomonas aeruginosa 1.267
Role of water during the extrusion of substrates by the efflux transporter AcrB 1.262
A framework for dissecting affinities of multidrug efflux transporter AcrB to fluoroquinolones 1.253
Structural analysis of hemoglobins and myoglobins using MD simulations 1.235
Impact of corpus callosum integrity on functional interhemispheric connectivity and cognition in healthy subjects 1.220
Meropenem vs. Imipenem interacting with MexB: structural and dynamical determinants of the efflux action on two substrates 1.172
Pathways to Exit a Receptor: Agonists and Delta-Oppioid Studied via Computer Simulations 1.112
Drug design: Insights from atomistic simulations 1.100
Erratum: Role of water during the extrusion of substrates by the efflux transporter AcrB (Journal of Physical Chemistry B (2011) 115 (8278-8287) DOI: 10.1021/jp200996x) 1.099
First-principles prediction of structure, energetics, formation enthalpy, elastic constants, polarization, and piezoelectric constants of AlN, GaN, and InN: Comparison of local and gradient-corrected density-functional theory 1.096
Breathing motions of a respiratory protein revealed by molecular dynamics simulation 1.091
Structural determinants of antibiotic and β-lactamase diffusion through bacterial porins 1.073
Effects of the F610A mutation on substrate extrusion in the AcrB transporter: explanation and rationale by molecular dynamics simulations 1.073
Bacterial efflux transporters’ polyspecificity – a gift and a curse? 1.069
Screening for antibiotics with enhanced permeation properties: proof of concept using molecular simulations 1.053
Functional Rotation of the Transporter AcrB: Insights into Drug Extrusion from Simulations 1.006
The Biophysics Of Antibiotics Translocation Through OmpF Revealed By Computer Simulations 1.006
Evidences of Xenon-Induced Structural Changes in the Active Site of Cyano-MetMyoglobins: A 1H NMR Study 993
Molecular motions in drug design: the coming age of the metadynamics method 973
Simulating Efflux Pumps: The Extrusion Mechanism of Substrates 937
Simulations of Copper-1,10-Phenanthroline Complexes Binding the DNA 933
Functional rotation of the transporter AcrB: Insights into drug extrusion from simulations 930
Potent flaviviridae inhibitors: targeted finger domain of RdRp 925
Potent flaviviridae inhibitors: targeted finger domain of RdRp. 925
CO escape from myoglobin with metadynamics simulations 912
AB-DB: Force-Field parameters, MD trajectories, QM-based data, and Descriptors of Antimicrobials 891
Molecular simulations of SSTR2 dynamics and interaction with ligands 883
Functional Rotation of the Transporter AcrB: The Essentials of Peristaltic Motion and Subsequent Substrate Extrusion 878
Mystery unveiled: benzimidazole docks different domains in Flaviviridae 851
A Molecular Approach to Ligand-Receptor Interaction 846
Different approaches for the structural and functional characterization of a double variant hemoglobin (HbG-Philadelphia/Duarte) 781
Molecular Recognition Routes Of DNA By Anticancer Ligands: Mechanisms and Free Energies Explored Via Molecular Dynamics Simulations 759
Hb G-Philadelphia/Duarte (alfa68 Asn→Lys beta62 Ala→Pro) a new double variant structural and functional properties. 718
Molecular insights into the Patched1 drug efflux inhibitory activity of panicein A hydroquinone: a computational study 713
Recognition of quinolone antibiotics by the multidrug efflux transporter MexB of Pseudomonas aeruginosa 705
Understanding anticancer Drug-DNA interactions via molecular dynamics simulations 686
Molecular rationale for the impairment of the MexAB-OprM efflux pump by a single mutation in MexA 684
Common recognition topology of mex transporters of Pseudomonas aeruginosa revealed by molecular modelling 673
Molecular simulations reveal the molecular basis of diffusion through porins; and allow designing potent antibiotics 669
null 662
Inhibition of the drug efflux activity of Ptch1 as a promising strategy to overcome chemotherapy resistance in cancer cells 653
Totale 204.600
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Categoria #
all - tutte 276.610
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 276.610
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202026.528 0 0 0 0 10.710 6.966 3.955 1.088 827 787 759 1.436
2020/202142.259 1.629 1.830 1.928 10.301 8.409 5.108 4.047 2.552 921 2.132 1.762 1.640
2021/20229.283 1.032 1.023 421 557 814 757 571 351 545 1.021 1.070 1.121
2022/202315.310 997 1.592 1.526 1.199 1.209 1.725 761 1.465 1.069 1.146 1.709 912
2023/202422.342 706 852 1.390 3.483 2.262 3.866 1.826 1.618 843 1.177 2.201 2.118
2024/202563.312 7.777 10.130 6.048 38.794 563 0 0 0 0 0 0 0
Totale 230.701