UNICA IRIS Institutional Research Information System

RUGGERONE, PAOLO
 Distribuzione geografica
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Continente #
EU - Europa 228.232
NA - Nord America 11.477
AS - Asia 4.003
SA - Sud America 788
AF - Africa 62
Continente sconosciuto - Info sul continente non disponibili 12
OC - Oceania 9
Totale 244.583
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Nazione #
IT - Italia 225.392
US - Stati Uniti d'America 11.235
CN - Cina 1.753
SG - Singapore 1.429
UA - Ucraina 840
BR - Brasile 662
SE - Svezia 582
GB - Regno Unito 468
DE - Germania 404
VN - Vietnam 269
FI - Finlandia 254
CA - Canada 194
KR - Corea 120
IN - India 108
FR - Francia 100
HK - Hong Kong 88
AR - Argentina 49
MX - Messico 32
BD - Bangladesh 29
TW - Taiwan 29
RU - Federazione Russa 28
AT - Austria 26
ZA - Sudafrica 25
JP - Giappone 24
BE - Belgio 23
IQ - Iraq 23
NL - Olanda 22
ID - Indonesia 21
TR - Turchia 20
EC - Ecuador 19
ES - Italia 19
PL - Polonia 18
CO - Colombia 14
EU - Europa 12
LT - Lituania 12
UZ - Uzbekistan 12
PK - Pakistan 11
UY - Uruguay 11
IR - Iran 10
PY - Paraguay 10
MA - Marocco 9
VE - Venezuela 9
AU - Australia 8
CH - Svizzera 8
PE - Perù 8
PH - Filippine 8
AZ - Azerbaigian 6
KE - Kenya 6
KG - Kirghizistan 6
LB - Libano 6
NP - Nepal 6
EG - Egitto 5
AE - Emirati Arabi Uniti 4
CL - Cile 4
DO - Repubblica Dominicana 4
JO - Giordania 4
NG - Nigeria 4
AM - Armenia 3
BH - Bahrain 3
IE - Irlanda 3
KW - Kuwait 3
LU - Lussemburgo 3
MU - Mauritius 3
NO - Norvegia 3
PA - Panama 3
PT - Portogallo 3
RO - Romania 3
RS - Serbia 3
TH - Thailandia 3
AO - Angola 2
BG - Bulgaria 2
BO - Bolivia 2
CZ - Repubblica Ceca 2
DZ - Algeria 2
EE - Estonia 2
HU - Ungheria 2
JM - Giamaica 2
MD - Moldavia 2
TN - Tunisia 2
AL - Albania 1
BA - Bosnia-Erzegovina 1
BS - Bahamas 1
CR - Costa Rica 1
CY - Cipro 1
ET - Etiopia 1
GI - Gibilterra 1
GR - Grecia 1
GT - Guatemala 1
HN - Honduras 1
HR - Croazia 1
HT - Haiti 1
IL - Israele 1
IS - Islanda 1
LY - Libia 1
ML - Mali 1
MT - Malta 1
NI - Nicaragua 1
NZ - Nuova Zelanda 1
OM - Oman 1
PS - Palestinian Territory 1
Totale 244.579
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Città #
Cagliari 216.981
Uta 7.714
Fairfield 1.313
Woodbridge 984
Ashburn 967
Chandler 664
Houston 646
Singapore 645
Dallas 611
Seattle 564
Boardman 553
Ann Arbor 542
Wilmington 519
Jacksonville 467
Cambridge 454
Nyköping 361
Beijing 335
Dearborn 327
Hefei 204
Nanjing 168
Los Angeles 163
Munich 162
Boston 140
Santa Clara 129
Mcallen 120
Seoul 117
Helsinki 110
Montréal 109
New York 99
The Dalles 91
Shanghai 86
Buffalo 80
Hong Kong 77
Milan 68
Dong Ket 66
Ho Chi Minh City 63
Redwood City 63
San Diego 62
Guangzhou 52
São Paulo 51
Shenyang 49
Nanchang 48
Hebei 45
Hanoi 43
Changsha 41
Chicago 39
Council Bluffs 39
Jiaxing 38
London 36
Redondo Beach 36
Fonni 31
Mountain View 31
Tianjin 31
Frankfurt am Main 29
Verona 29
Falls Church 27
Washington 27
New Taipei 26
Sassari 26
Toronto 26
Phoenix 25
Zhengzhou 25
Rio de Janeiro 23
Rome 23
Cedar Knolls 22
Orange 22
Jinan 20
Norwalk 20
Winnipeg 20
Brussels 19
Chennai 17
Columbus 17
Kunming 17
Ottawa 17
Tokyo 17
Belo Horizonte 16
Ningbo 16
Denver 15
Nuremberg 15
Norman 14
Pune 14
Warsaw 14
Marseille 13
Stockholm 13
Vienna 13
Johannesburg 12
San Francisco 12
Taizhou 12
Wuhan 12
Atlanta 11
Curitiba 11
Haiphong 11
Jakarta 11
Montreal 11
Tashkent 11
Brooklyn 10
Hangzhou 10
San Jose 10
Turku 10
Hải Dương 9
Totale 238.234
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Nome #
Different molecular mechanisms of inhibition of bovine viral diarrhea virus and hepatitis C virus RNA-dependent RNA polymerases by a novel benzimidazole 36.815
Structure-Activity Relationship Study of Hydroxycoumarins and Mushroom Tyrosinase 4.670
A database of force-field parameters, dynamics, and properties of antimicrobial compounds 3.997
Multidrug efflux pumps and their inhibitors characterized by computational modeling 3.939
Insights into the homo-oligomerization properties of N-terminal coiled-coil domain of Ebola virus VP35 protein 3.232
Water-mediated interactions enable smooth substrate transport in a bacterial efflux pump 3.040
Molecular basis for the different interactions of congeneric substrates with the polyspecific transporter AcrB 3.039
Computer simulations of the activity of RND efflux pumps 3.009
Molecular Rationale behind the Differential Substrate Specificity of Bacterial RND Multi-Drug Transporters 2.989
Relevance of Ebola virus VP35 homo-dimerization on the type I interferon cascade inhibition 2.988
A novel dendrimeric peptide with antimicrobial properties: structure-function analysis of SB056 2.976
Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives 2.947
Computational modelling of efflux pumps and their inhibitors 2.884
Molecular Modeling of Multidrug Properties of Resistance Nodulation Division (RND) Transporters 2.882
Molecular Determinants of the Promiscuity of MexB and MexY Multidrug Transporters of Pseudomonas aeruginosa 2.875
A Novel Dendrimeric Peptide with Antimicrobial Properties: Structure-Function Analysis of SB056 2.823
Molecular Interactions of Cephalosporins with the Deep Binding Pocket of the RND Transporter AcrB 2.807
A New Critical Conformational Determinant of Multidrug Efflux by an MFS Transporter 2.803
Insights into Ebola VP35 oligomerization from molecular simulations 2.771
Molecular dynamics computer simulations of multidrug RND efflux pumps 2.729
Computational study of correlated domain motions in the AcrB efflux transporter 2.685
Structural and functional characterization of a new double variant haemoglobin (HbG-Philadelphia/Duarte α268Asn→Lys β262Ala→Pro) 2.683
AcrB drug-binding pocket substitution confers clinically relevant resistance and altered substrate specificity 2.639
Identification and characterization of carbapenem binding sites within the RND-transporter AcrB 2.587
Analysis of fast channel blockage: revealing substrate binding in the microsecond range 2.574
Molecular mechanism of MBX2319 inhibition of Escherichia coli AcrB multidrug efflux pump and comparison with other inhibitors 2.526
RND efflux pumps: structural information translated into function and inhibition mechanisms 2.427
Folding and Self-Assembly of the Pore-Forming Unit Tat-A of the Bacterial Twin-Arginine Translocase 2.319
Modeling Assembly of the Tata Pore Forming Complex using an Implicit Membrane Model 2.292
Binding and Transport of Carboxylated Drugs by the Multidrug Transporter AcrB 2.214
The challenge of intracellular antibiotic accumulation, a function of fluoroquinolone influx versus bacterial efflux 2.145
A kinetic Monte Carlo approach to investigate antibiotic translocation through bacterial porins 2.131
Folding and self-assembly of the TatA translocation pore based on a charge zipper mechanism 2.088
Mechanism of Inhibition By, and of Drug Resistance to, a Benzimidazole Inhibitor of the RNA-Dependent RNA Polymerase of Bovine Viral Diarrhoea Virus 2.084
Interaction of antibacterial compounds with RND efflux pumps in Pseudomonas aeruginosa 2.035
Molecular Mechanism of Viral Resistance to a Potent Non-nucleoside Inhibitor Unveiled by Molecular Simulations 2.002
Chlorpromazine and amitriptyline are substrates and inhibitors of the acrb multidrug efflux pump 1.966
Pathways to exit a receptor: a dynamical view of agonists - delta-opioids interaction 1.944
Molecular interactions of carbapenem antibiotics with the multidrug efflux transporter acrb of escherichia coli 1.930
Effects of Point Mutations on the Activity of AcrB 1.890
Molecular simulations reveal the mechanism and the determinants for ampicillin translocation through OmpF 1.876
Using Molecular Simulations to Screen for Antibiotics with Enhanced Permeation Properties through Bacterial Pores 1.862
Exploring Binding Properties of Agonists Interacting with a δ-Opioid Receptor 1.809
Heme proteins: the role of solvent on the dynamics of gates and portals 1.732
Investigating reaction pathways in rare events simulations of antibiotics diffusion through protein channels 1.717
Towards screening for antibiotics with enhanced permeation properties through bacterial porins 1.692
Point Mutation I261M Affects the Dynamics of BVDV and its Interaction with Benzimidazole Antiviral 227G 1.691
null 1.683
Structural and dynamical properties of the porins OmpF and OmpC: insights from molecular simulations 1.633
Recognition of imipenem and meropenem by the RND-transporter MexB studied by computer simulations 1.614
Bridging time and length scales: from macroscopic flux to molecular mechanism of antibiotics diffusion through porins 1.602
Cryo-EM structure and molecular dynamics analysis of the fluoroquinolone resistant mutant of the AcrB transporter from salmonella 1.569
Structural Determinants Of Antibiotic And betalactamase Diffusion Through Bacterial Porins 1.505
Structural determinants of antibiotic translocations in OMPF 1.471
Perturbed structural dynamics underlie inhibition and altered efflux of the multidrug resistance pump AcrB 1.468
Mechanism of inhibition by, and drug resistance to, a benzimidazole inhibitor of the Rna-dependent-Rna-polymerase of Bovine Viral Diarrhoea virus 1.412
A framework for dissecting affinities of multidrug efflux transporter AcrB to fluoroquinolones 1.404
Predictive rules of efflux inhibition and avoidance in Pseudomonas aeruginosa 1.378
Impact of corpus callosum integrity on functional interhemispheric connectivity and cognition in healthy subjects 1.377
Advanced computational methods in molecular medicine 1.362
null 1.359
Role of water during the extrusion of substrates by the efflux transporter AcrB 1.357
Simulating bacterial efflux: how molecular features affect functional rotation 1.347
Structural analysis of hemoglobins and myoglobins using MD simulations 1.307
Meropenem vs. Imipenem interacting with MexB: structural and dynamical determinants of the efflux action on two substrates 1.246
Bacterial efflux transporters’ polyspecificity – a gift and a curse? 1.230
Pathways to Exit a Receptor: Agonists and Delta-Oppioid Studied via Computer Simulations 1.210
Drug design: Insights from atomistic simulations 1.186
First-principles prediction of structure, energetics, formation enthalpy, elastic constants, polarization, and piezoelectric constants of AlN, GaN, and InN: Comparison of local and gradient-corrected density-functional theory 1.166
Structural determinants of antibiotic and β-lactamase diffusion through bacterial porins 1.157
Erratum: Role of water during the extrusion of substrates by the efflux transporter AcrB (Journal of Physical Chemistry B (2011) 115 (8278-8287) DOI: 10.1021/jp200996x) 1.157
Breathing motions of a respiratory protein revealed by molecular dynamics simulation 1.155
Effects of the F610A mutation on substrate extrusion in the AcrB transporter: explanation and rationale by molecular dynamics simulations 1.142
Screening for antibiotics with enhanced permeation properties: proof of concept using molecular simulations 1.107
Functional Rotation of the Transporter AcrB: Insights into Drug Extrusion from Simulations 1.092
Evidences of Xenon-Induced Structural Changes in the Active Site of Cyano-MetMyoglobins: A 1H NMR Study 1.089
Molecular simulations of SSTR2 dynamics and interaction with ligands 1.076
The Biophysics Of Antibiotics Translocation Through OmpF Revealed By Computer Simulations 1.072
AB-DB: Force-Field parameters, MD trajectories, QM-based data, and Descriptors of Antimicrobials 1.069
Molecular motions in drug design: the coming age of the metadynamics method 1.046
Simulations of Copper-1,10-Phenanthroline Complexes Binding the DNA 1.009
Simulating Efflux Pumps: The Extrusion Mechanism of Substrates 1.004
Functional rotation of the transporter AcrB: Insights into drug extrusion from simulations 998
Potent flaviviridae inhibitors: targeted finger domain of RdRp. 988
CO escape from myoglobin with metadynamics simulations 984
Potent flaviviridae inhibitors: targeted finger domain of RdRp 974
Functional Rotation of the Transporter AcrB: The Essentials of Peristaltic Motion and Subsequent Substrate Extrusion 942
A Molecular Approach to Ligand-Receptor Interaction 932
Mystery unveiled: benzimidazole docks different domains in Flaviviridae 911
Recognition of quinolone antibiotics by the multidrug efflux transporter MexB of Pseudomonas aeruginosa 871
Common recognition topology of mex transporters of Pseudomonas aeruginosa revealed by molecular modelling 846
Different approaches for the structural and functional characterization of a double variant hemoglobin (HbG-Philadelphia/Duarte) 832
Molecular rationale for the impairment of the MexAB-OprM efflux pump by a single mutation in MexA 822
Molecular Recognition Routes Of DNA By Anticancer Ligands: Mechanisms and Free Energies Explored Via Molecular Dynamics Simulations 811
Molecular insights into the Patched1 drug efflux inhibitory activity of panicein A hydroquinone: a computational study 811
Inhibition of the drug efflux activity of Ptch1 as a promising strategy to overcome chemotherapy resistance in cancer cells 805
Tripartite efflux pumps of the RND superfamily: what did we learn from computational studies? 773
Hb G-Philadelphia/Duarte (alfa68 Asn→Lys beta62 Ala→Pro) a new double variant structural and functional properties. 770
Understanding anticancer Drug-DNA interactions via molecular dynamics simulations 738
Molecular simulations reveal the molecular basis of diffusion through porins; and allow designing potent antibiotics 720
Totale 214.344
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Categoria #
all - tutte 306.733
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 306.733
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202118.162 0 0 0 0 0 5.108 4.047 2.552 921 2.132 1.762 1.640
2021/20229.283 1.032 1.023 421 557 814 757 571 351 545 1.021 1.070 1.121
2022/202315.310 997 1.592 1.526 1.199 1.209 1.725 761 1.465 1.069 1.146 1.709 912
2023/202422.342 706 852 1.390 3.483 2.262 3.866 1.826 1.618 843 1.177 2.201 2.118
2024/202572.889 7.777 10.130 6.048 38.794 2.552 2.601 3.298 211 342 278 366 492
2025/20264.737 623 400 1.412 926 810 566 0 0 0 0 0 0
Totale 245.015