UNICA IRIS Institutional Research Information System

RUGGERONE, PAOLO
 Distribuzione geografica
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Continente #
EU - Europa 152.034
NA - Nord America 9.115
AS - Asia 994
Continente sconosciuto - Info sul continente non disponibili 12
OC - Oceania 8
AF - Africa 4
SA - Sud America 3
Totale 162.170
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Nazione #
IT - Italia 149.573
US - Stati Uniti d'America 8.971
UA - Ucraina 832
CN - Cina 770
SE - Svezia 548
GB - Regno Unito 417
DE - Germania 301
FI - Finlandia 221
CA - Canada 142
FR - Francia 69
VN - Vietnam 68
IN - India 55
SG - Singapore 43
TW - Taiwan 27
BE - Belgio 17
NL - Olanda 15
EU - Europa 12
RU - Federazione Russa 12
IR - Iran 8
AU - Australia 7
CH - Svizzera 7
JP - Giappone 6
ES - Italia 5
AT - Austria 4
TR - Turchia 4
IE - Irlanda 3
PH - Filippine 3
BG - Bulgaria 2
HK - Hong Kong 2
LU - Lussemburgo 2
MU - Mauritius 2
NG - Nigeria 2
TH - Thailandia 2
BR - Brasile 1
CO - Colombia 1
CY - Cipro 1
GT - Guatemala 1
HR - Croazia 1
HU - Ungheria 1
ID - Indonesia 1
IL - Israele 1
IQ - Iraq 1
IS - Islanda 1
KR - Corea 1
LB - Libano 1
MX - Messico 1
NZ - Nuova Zelanda 1
PL - Polonia 1
PT - Portogallo 1
PY - Paraguay 1
RO - Romania 1
Totale 162.170
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Città #
Cagliari 148.944
Fairfield 1.313
Woodbridge 984
Ashburn 689
Chandler 664
Houston 643
Seattle 559
Ann Arbor 542
Wilmington 518
Jacksonville 467
Cambridge 454
Nyköping 358
Dearborn 327
Boardman 205
Nanjing 167
Boston 125
Mcallen 120
Munich 113
Montréal 109
Beijing 101
Helsinki 93
New York 68
Dong Ket 66
Milan 63
Redwood City 63
San Diego 62
Nanchang 48
Shenyang 48
Hebei 45
Shanghai 45
Changsha 39
Guangzhou 38
Jiaxing 33
Fonni 31
Mountain View 31
London 30
Falls Church 27
Hefei 27
Verona 27
New Taipei 26
Sassari 26
Tianjin 26
Washington 25
Zhengzhou 24
Cedar Knolls 22
Orange 22
Jinan 20
Norwalk 20
Rome 19
Toronto 19
Kunming 16
Phoenix 16
Brussels 15
Ningbo 15
Chicago 14
Norman 14
Marseille 13
Pune 13
Taizhou 12
Ottawa 11
Los Angeles 9
Redmond 9
Auburn Hills 8
Quartu Sant'elena 8
Hangzhou 7
Kilburn 7
Stockholm 7
Fuzhou 6
Indiana 6
Napoli 6
Saint Petersburg 6
Walnut 6
Bologna 5
Hounslow 5
Liverpool 5
Tonara 5
Wuhan 5
Carbonia 4
Edinburgh 4
Patna 4
San Francisco 4
Sinnai 4
Vienna 4
Zurich 4
Alameda 3
Amsterdam 3
Borås 3
Brisbane 3
Casamicciola Terme 3
Chengdu 3
Chiswick 3
Dallas 3
Dublin 3
Elsdorf 3
Iglesias 3
Karlsruhe 3
Kochi 3
Lund 3
Monserrato 3
Mumbai 3
Totale 158.860
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Nome #
Structure-Activity Relationship Study of Hydroxycoumarins and Mushroom Tyrosinase 4.135
A database of force-field parameters, dynamics, and properties of antimicrobial compounds 3.575
Different molecular mechanisms of inhibition of bovine viral diarrhea virus and hepatitis C virus RNA-dependent RNA polymerases by a novel benzimidazole 3.190
Multidrug efflux pumps and their inhibitors characterized by computational modeling 2.940
Insights into the homo-oligomerization properties of N-terminal coiled-coil domain of Ebola virus VP35 protein 2.823
A novel dendrimeric peptide with antimicrobial properties: structure-function analysis of SB056 2.692
Molecular basis for the different interactions of congeneric substrates with the polyspecific transporter AcrB 2.572
Computer simulations of the activity of RND efflux pumps 2.507
Molecular Modeling of Multidrug Properties of Resistance Nodulation Division (RND) Transporters 2.484
Relevance of Ebola virus VP35 homo-dimerization on the type I interferon cascade inhibition 2.457
Computational modelling of efflux pumps and their inhibitors 2.449
A Novel Dendrimeric Peptide with Antimicrobial Properties: Structure-Function Analysis of SB056 2.448
Molecular Rationale behind the Differential Substrate Specificity of Bacterial RND Multi-Drug Transporters 2.426
Water-mediated interactions enable smooth substrate transport in a bacterial efflux pump 2.417
Molecular dynamics computer simulations of multidrug RND efflux pumps 2.381
Structural and functional characterization of a new double variant haemoglobin (HbG-Philadelphia/Duarte α268Asn→Lys β262Ala→Pro) 2.374
Insights into Ebola VP35 oligomerization from molecular simulations 2.327
A New Critical Conformational Determinant of Multidrug Efflux by an MFS Transporter 2.323
Molecular Interactions of Cephalosporins with the Deep Binding Pocket of the RND Transporter AcrB 2.314
Analysis of fast channel blockage: revealing substrate binding in the microsecond range 2.308
AcrB drug-binding pocket substitution confers clinically relevant resistance and altered substrate specificity 2.243
Identification and characterization of carbapenem binding sites within the RND-transporter AcrB 2.215
Molecular Determinants of the Promiscuity of MexB and MexY Multidrug Transporters of Pseudomonas aeruginosa 2.213
Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives 2.113
Folding and Self-Assembly of the Pore-Forming Unit Tat-A of the Bacterial Twin-Arginine Translocase 2.093
Computational study of correlated domain motions in the AcrB efflux transporter 2.032
Molecular mechanism of MBX2319 inhibition of Escherichia coli AcrB multidrug efflux pump and comparison with other inhibitors 1.976
RND efflux pumps: structural information translated into function and inhibition mechanisms 1.923
Modeling Assembly of the Tata Pore Forming Complex using an Implicit Membrane Model 1.796
A kinetic Monte Carlo approach to investigate antibiotic translocation through bacterial porins 1.792
Mechanism of Inhibition By, and of Drug Resistance to, a Benzimidazole Inhibitor of the RNA-Dependent RNA Polymerase of Bovine Viral Diarrhoea Virus 1.770
Folding and self-assembly of the TatA translocation pore based on a charge zipper mechanism 1.762
null 1.683
Molecular Mechanism of Viral Resistance to a Potent Non-nucleoside Inhibitor Unveiled by Molecular Simulations 1.647
Binding and Transport of Carboxylated Drugs by the Multidrug Transporter AcrB 1.627
Effects of Point Mutations on the Activity of AcrB 1.600
Molecular interactions of carbapenem antibiotics with the multidrug efflux transporter acrb of escherichia coli 1.589
Exploring Binding Properties of Agonists Interacting with a δ-Opioid Receptor 1.587
Heme proteins: the role of solvent on the dynamics of gates and portals 1.507
Interaction of antibacterial compounds with RND efflux pumps in Pseudomonas aeruginosa 1.506
The challenge of intracellular antibiotic accumulation, a function of fluoroquinolone influx versus bacterial efflux 1.503
Point Mutation I261M Affects the Dynamics of BVDV and its Interaction with Benzimidazole Antiviral 227G 1.495
Molecular simulations reveal the mechanism and the determinants for ampicillin translocation through OmpF 1.411
Structural and dynamical properties of the porins OmpF and OmpC: insights from molecular simulations 1.411
Investigating reaction pathways in rare events simulations of antibiotics diffusion through protein channels 1.393
null 1.359
Recognition of imipenem and meropenem by the RND-transporter MexB studied by computer simulations 1.301
Using Molecular Simulations to Screen for Antibiotics with Enhanced Permeation Properties through Bacterial Pores 1.294
Bridging time and length scales: from macroscopic flux to molecular mechanism of antibiotics diffusion through porins 1.276
Mechanism of inhibition by, and drug resistance to, a benzimidazole inhibitor of the Rna-dependent-Rna-polymerase of Bovine Viral Diarrhoea virus 1.258
Advanced computational methods in molecular medicine 1.228
Structural Determinants Of Antibiotic And betalactamase Diffusion Through Bacterial Porins 1.190
Chlorpromazine and amitriptyline are substrates and inhibitors of the acrb multidrug efflux pump 1.169
Cryo-EM structure and molecular dynamics analysis of the fluoroquinolone resistant mutant of the AcrB transporter from salmonella 1.135
Structural analysis of hemoglobins and myoglobins using MD simulations 1.107
Simulating bacterial efflux: how molecular features affect functional rotation 1.089
Role of water during the extrusion of substrates by the efflux transporter AcrB 1.045
Structural determinants of antibiotic translocations in OMPF 1.010
Breathing motions of a respiratory protein revealed by molecular dynamics simulation 992
Screening for antibiotics with enhanced permeation properties: proof of concept using molecular simulations 985
Towards screening for antibiotics with enhanced permeation properties through bacterial porins 985
First-principles prediction of structure, energetics, formation enthalpy, elastic constants, polarization, and piezoelectric constants of AlN, GaN, and InN: Comparison of local and gradient-corrected density-functional theory 979
Drug design: Insights from atomistic simulations 972
Pathways to Exit a Receptor: Agonists and Delta-Oppioid Studied via Computer Simulations 956
Meropenem vs. Imipenem interacting with MexB: structural and dynamical determinants of the efflux action on two substrates 953
The Biophysics Of Antibiotics Translocation Through OmpF Revealed By Computer Simulations 932
Structural determinants of antibiotic and β-lactamase diffusion through bacterial porins 924
Erratum: Role of water during the extrusion of substrates by the efflux transporter AcrB (Journal of Physical Chemistry B (2011) 115 (8278-8287) DOI: 10.1021/jp200996x) 918
Effects of the F610A mutation on substrate extrusion in the AcrB transporter: explanation and rationale by molecular dynamics simulations 881
Perturbed structural dynamics underlie inhibition and altered efflux of the multidrug resistance pump AcrB 876
Pathways to exit a receptor: a dynamical view of agonists - delta-opioids interaction 871
Evidences of Xenon-Induced Structural Changes in the Active Site of Cyano-MetMyoglobins: A 1H NMR Study 849
Potent flaviviridae inhibitors: targeted finger domain of RdRp 846
CO escape from myoglobin with metadynamics simulations 842
Molecular motions in drug design: the coming age of the metadynamics method 831
Predictive rules of efflux inhibition and avoidance in Pseudomonas aeruginosa 825
Functional Rotation of the Transporter AcrB: Insights into Drug Extrusion from Simulations 818
Potent flaviviridae inhibitors: targeted finger domain of RdRp. 812
Simulating Efflux Pumps: The Extrusion Mechanism of Substrates 803
Functional rotation of the transporter AcrB: Insights into drug extrusion from simulations 753
Simulations of Copper-1,10-Phenanthroline Complexes Binding the DNA 739
A Molecular Approach to Ligand-Receptor Interaction 727
Mystery unveiled: benzimidazole docks different domains in Flaviviridae 721
Functional Rotation of the Transporter AcrB: The Essentials of Peristaltic Motion and Subsequent Substrate Extrusion 707
Different approaches for the structural and functional characterization of a double variant hemoglobin (HbG-Philadelphia/Duarte) 690
Bacterial efflux transporters’ polyspecificity – a gift and a curse? 663
null 662
Hb G-Philadelphia/Duarte (alfa68 Asn→Lys beta62 Ala→Pro) a new double variant structural and functional properties. 630
Molecular simulations reveal the molecular basis of diffusion through porins; and allow designing potent antibiotics 619
Molecular Recognition Routes Of DNA By Anticancer Ligands: Mechanisms and Free Energies Explored Via Molecular Dynamics Simulations 619
Surface phonon calculation for Si (111):H (1x1) 543
Structural analysis of cavities in myoglobin via NMR and numerical simulations. 526
Structure-function relationship in a naturally occurring mutated hemoglobin: a combined numerical-experimental approach 518
Understanding anticancer Drug-DNA interactions via molecular dynamics simulations 514
null 505
Dynamics of extensively reconstructed surfaces: Si(111) 2×1 489
null 480
IDENTIFICATION AND CHARACTERIZATION OF A NEW DOUBLE VARIANT HEMOGLOBIN (HbG-PHILADELPHIA/DUARTE ALFA2 68 ASN→LYS BETA2 62ALA→PRO 460
null 453
Frustrated H-induced instability of Mo(110) 446
Totale 143.804
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Categoria #
all - tutte 200.152
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 200.152
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/20191.994 0 0 0 0 0 0 0 0 0 506 849 639
2019/202030.316 1.744 1.143 227 674 10.710 6.966 3.955 1.088 827 787 759 1.436
2020/202142.259 1.629 1.830 1.928 10.301 8.409 5.108 4.047 2.552 921 2.132 1.762 1.640
2021/20229.283 1.032 1.023 421 557 814 757 571 351 545 1.021 1.070 1.121
2022/202315.293 995 1.590 1.523 1.198 1.208 1.724 760 1.461 1.069 1.146 1.707 912
2023/202417.513 706 848 1.389 3.481 2.260 3.856 1.824 1.618 842 689 0 0
Totale 162.543