UNICA IRIS Institutional Research Information System

RUGGERONE, PAOLO
 Distribuzione geografica
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Continente #
EU - Europa 231.804
NA - Nord America 12.607
AS - Asia 5.199
SA - Sud America 933
AF - Africa 117
Continente sconosciuto - Info sul continente non disponibili 12
OC - Oceania 10
Totale 250.682
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Nazione #
IT - Italia 228.585
US - Stati Uniti d'America 12.343
CN - Cina 1.921
SG - Singapore 1.812
UA - Ucraina 846
BR - Brasile 737
SE - Svezia 594
GB - Regno Unito 479
VN - Vietnam 479
DE - Germania 435
FI - Finlandia 358
FR - Francia 264
HK - Hong Kong 214
CA - Canada 203
IN - India 169
KR - Corea 121
BD - Bangladesh 70
IQ - Iraq 67
AR - Argentina 66
MX - Messico 38
PK - Pakistan 37
ID - Indonesia 34
JP - Giappone 34
TR - Turchia 34
ZA - Sudafrica 34
NL - Olanda 33
EC - Ecuador 32
RU - Federazione Russa 32
TW - Taiwan 31
UZ - Uzbekistan 30
AT - Austria 29
CO - Colombia 29
ES - Italia 28
BE - Belgio 23
PH - Filippine 23
PL - Polonia 22
VE - Venezuela 18
UY - Uruguay 16
JO - Giordania 15
EG - Egitto 13
MA - Marocco 13
PE - Perù 13
EU - Europa 12
LT - Lituania 12
PY - Paraguay 12
SA - Arabia Saudita 12
KE - Kenya 11
NP - Nepal 11
AZ - Azerbaigian 10
IR - Iran 10
AU - Australia 9
CH - Svizzera 9
TN - Tunisia 9
AE - Emirati Arabi Uniti 8
CL - Cile 8
DZ - Algeria 8
ET - Etiopia 7
MY - Malesia 7
RS - Serbia 7
TH - Thailandia 7
BH - Bahrain 6
DO - Repubblica Dominicana 6
IE - Irlanda 6
KG - Kirghizistan 6
LB - Libano 6
AO - Angola 5
MU - Mauritius 5
NG - Nigeria 5
PS - Palestinian Territory 5
MD - Moldavia 4
NO - Norvegia 4
PA - Panama 4
PT - Portogallo 4
RO - Romania 4
AM - Armenia 3
HN - Honduras 3
HR - Croazia 3
JM - Giamaica 3
KW - Kuwait 3
KZ - Kazakistan 3
LU - Lussemburgo 3
SY - Repubblica araba siriana 3
AL - Albania 2
BA - Bosnia-Erzegovina 2
BG - Bulgaria 2
BO - Bolivia 2
CZ - Repubblica Ceca 2
EE - Estonia 2
GR - Grecia 2
GT - Guatemala 2
HU - Ungheria 2
IL - Israele 2
OM - Oman 2
SN - Senegal 2
BS - Bahamas 1
BY - Bielorussia 1
CI - Costa d'Avorio 1
CR - Costa Rica 1
CY - Cipro 1
GI - Gibilterra 1
Totale 250.667
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Città #
Cagliari 220.136
Uta 7.714
Fairfield 1.313
Ashburn 1.103
Woodbridge 984
Singapore 917
Chandler 664
San Jose 659
Houston 646
Dallas 616
Seattle 564
Boardman 556
Ann Arbor 542
Wilmington 520
Jacksonville 467
Cambridge 455
Nyköping 361
Beijing 346
Dearborn 327
Helsinki 212
Hefei 204
Los Angeles 203
Hong Kong 188
Nanjing 169
Munich 162
Lauterbourg 148
The Dalles 143
Boston 141
Santa Clara 138
Ho Chi Minh City 130
Mcallen 120
Seoul 117
New York 113
Montréal 109
Council Bluffs 106
Hanoi 92
Shanghai 91
Buffalo 83
Milan 70
Dong Ket 66
Redwood City 63
San Diego 62
Guangzhou 59
São Paulo 57
Shenyang 50
Frankfurt am Main 49
Nanchang 48
Hebei 45
Chicago 44
Changsha 43
Jiaxing 39
London 39
Redondo Beach 36
Tianjin 35
Orem 34
Fonni 31
Mountain View 31
Baghdad 30
Verona 29
Phoenix 28
Toronto 28
Falls Church 27
Washington 27
New Taipei 26
Rome 26
Sassari 26
Tashkent 26
Zhengzhou 26
Chennai 25
Rio de Janeiro 24
Tokyo 24
Cedar Knolls 22
Orange 22
Jinan 21
Norwalk 20
Winnipeg 20
Brussels 19
Haiphong 18
Ottawa 18
Belo Horizonte 17
Columbus 17
Kunming 17
Nuremberg 17
Ningbo 16
Pune 16
Warsaw 16
Denver 15
Lahore 15
Da Nang 14
Johannesburg 14
Marseille 14
Montreal 14
Norman 14
Vienna 14
Amman 13
Amsterdam 13
Atlanta 13
Brooklyn 13
Stockholm 13
Dhaka 12
Totale 243.299
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Nome #
Different molecular mechanisms of inhibition of bovine viral diarrhea virus and hepatitis C virus RNA-dependent RNA polymerases by a novel benzimidazole 36.857
Structure-Activity Relationship Study of Hydroxycoumarins and Mushroom Tyrosinase 4.704
A database of force-field parameters, dynamics, and properties of antimicrobial compounds 4.048
Multidrug efflux pumps and their inhibitors characterized by computational modeling 3.983
Insights into the homo-oligomerization properties of N-terminal coiled-coil domain of Ebola virus VP35 protein 3.275
Water-mediated interactions enable smooth substrate transport in a bacterial efflux pump 3.081
Molecular basis for the different interactions of congeneric substrates with the polyspecific transporter AcrB 3.075
Relevance of Ebola virus VP35 homo-dimerization on the type I interferon cascade inhibition 3.044
Computer simulations of the activity of RND efflux pumps 3.037
Molecular Rationale behind the Differential Substrate Specificity of Bacterial RND Multi-Drug Transporters 3.031
A novel dendrimeric peptide with antimicrobial properties: structure-function analysis of SB056 3.029
Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives 2.980
Computational modelling of efflux pumps and their inhibitors 2.932
Molecular Modeling of Multidrug Properties of Resistance Nodulation Division (RND) Transporters 2.921
Molecular Determinants of the Promiscuity of MexB and MexY Multidrug Transporters of Pseudomonas aeruginosa 2.904
A Novel Dendrimeric Peptide with Antimicrobial Properties: Structure-Function Analysis of SB056 2.864
Molecular Interactions of Cephalosporins with the Deep Binding Pocket of the RND Transporter AcrB 2.846
A New Critical Conformational Determinant of Multidrug Efflux by an MFS Transporter 2.844
Insights into Ebola VP35 oligomerization from molecular simulations 2.816
Molecular dynamics computer simulations of multidrug RND efflux pumps 2.771
Structural and functional characterization of a new double variant haemoglobin (HbG-Philadelphia/Duarte α268Asn→Lys β262Ala→Pro) 2.730
Computational study of correlated domain motions in the AcrB efflux transporter 2.715
AcrB drug-binding pocket substitution confers clinically relevant resistance and altered substrate specificity 2.674
Identification and characterization of carbapenem binding sites within the RND-transporter AcrB 2.630
Analysis of fast channel blockage: revealing substrate binding in the microsecond range 2.614
Molecular mechanism of MBX2319 inhibition of Escherichia coli AcrB multidrug efflux pump and comparison with other inhibitors 2.577
RND efflux pumps: structural information translated into function and inhibition mechanisms 2.471
Folding and Self-Assembly of the Pore-Forming Unit Tat-A of the Bacterial Twin-Arginine Translocase 2.347
Modeling Assembly of the Tata Pore Forming Complex using an Implicit Membrane Model 2.329
Binding and Transport of Carboxylated Drugs by the Multidrug Transporter AcrB 2.233
The challenge of intracellular antibiotic accumulation, a function of fluoroquinolone influx versus bacterial efflux 2.191
A kinetic Monte Carlo approach to investigate antibiotic translocation through bacterial porins 2.181
Folding and self-assembly of the TatA translocation pore based on a charge zipper mechanism 2.130
Mechanism of Inhibition By, and of Drug Resistance to, a Benzimidazole Inhibitor of the RNA-Dependent RNA Polymerase of Bovine Viral Diarrhoea Virus 2.122
Interaction of antibacterial compounds with RND efflux pumps in Pseudomonas aeruginosa 2.068
Molecular Mechanism of Viral Resistance to a Potent Non-nucleoside Inhibitor Unveiled by Molecular Simulations 2.037
Chlorpromazine and amitriptyline are substrates and inhibitors of the acrb multidrug efflux pump 2.001
Pathways to exit a receptor: a dynamical view of agonists - delta-opioids interaction 1.979
Molecular interactions of carbapenem antibiotics with the multidrug efflux transporter acrb of escherichia coli 1.961
Effects of Point Mutations on the Activity of AcrB 1.933
Molecular simulations reveal the mechanism and the determinants for ampicillin translocation through OmpF 1.906
Using Molecular Simulations to Screen for Antibiotics with Enhanced Permeation Properties through Bacterial Pores 1.901
Exploring Binding Properties of Agonists Interacting with a δ-Opioid Receptor 1.831
Heme proteins: the role of solvent on the dynamics of gates and portals 1.762
Investigating reaction pathways in rare events simulations of antibiotics diffusion through protein channels 1.743
Point Mutation I261M Affects the Dynamics of BVDV and its Interaction with Benzimidazole Antiviral 227G 1.738
Towards screening for antibiotics with enhanced permeation properties through bacterial porins 1.722
null 1.683
Structural and dynamical properties of the porins OmpF and OmpC: insights from molecular simulations 1.673
Recognition of imipenem and meropenem by the RND-transporter MexB studied by computer simulations 1.649
Bridging time and length scales: from macroscopic flux to molecular mechanism of antibiotics diffusion through porins 1.622
Cryo-EM structure and molecular dynamics analysis of the fluoroquinolone resistant mutant of the AcrB transporter from salmonella 1.592
Structural Determinants Of Antibiotic And betalactamase Diffusion Through Bacterial Porins 1.530
Perturbed structural dynamics underlie inhibition and altered efflux of the multidrug resistance pump AcrB 1.510
Structural determinants of antibiotic translocations in OMPF 1.506
Mechanism of inhibition by, and drug resistance to, a benzimidazole inhibitor of the Rna-dependent-Rna-polymerase of Bovine Viral Diarrhoea virus 1.449
Impact of corpus callosum integrity on functional interhemispheric connectivity and cognition in healthy subjects 1.445
A framework for dissecting affinities of multidrug efflux transporter AcrB to fluoroquinolones 1.441
Predictive rules of efflux inhibition and avoidance in Pseudomonas aeruginosa 1.421
Advanced computational methods in molecular medicine 1.397
Role of water during the extrusion of substrates by the efflux transporter AcrB 1.394
Simulating bacterial efflux: how molecular features affect functional rotation 1.374
null 1.359
Structural analysis of hemoglobins and myoglobins using MD simulations 1.351
Meropenem vs. Imipenem interacting with MexB: structural and dynamical determinants of the efflux action on two substrates 1.289
Bacterial efflux transporters’ polyspecificity – a gift and a curse? 1.261
Pathways to Exit a Receptor: Agonists and Delta-Oppioid Studied via Computer Simulations 1.249
Drug design: Insights from atomistic simulations 1.235
First-principles prediction of structure, energetics, formation enthalpy, elastic constants, polarization, and piezoelectric constants of AlN, GaN, and InN: Comparison of local and gradient-corrected density-functional theory 1.203
Structural determinants of antibiotic and β-lactamase diffusion through bacterial porins 1.199
Erratum: Role of water during the extrusion of substrates by the efflux transporter AcrB (Journal of Physical Chemistry B (2011) 115 (8278-8287) DOI: 10.1021/jp200996x) 1.183
Breathing motions of a respiratory protein revealed by molecular dynamics simulation 1.179
Effects of the F610A mutation on substrate extrusion in the AcrB transporter: explanation and rationale by molecular dynamics simulations 1.175
Screening for antibiotics with enhanced permeation properties: proof of concept using molecular simulations 1.141
Functional Rotation of the Transporter AcrB: Insights into Drug Extrusion from Simulations 1.133
Molecular simulations of SSTR2 dynamics and interaction with ligands 1.124
Evidences of Xenon-Induced Structural Changes in the Active Site of Cyano-MetMyoglobins: A 1H NMR Study 1.118
The Biophysics Of Antibiotics Translocation Through OmpF Revealed By Computer Simulations 1.114
AB-DB: Force-Field parameters, MD trajectories, QM-based data, and Descriptors of Antimicrobials 1.113
Molecular motions in drug design: the coming age of the metadynamics method 1.084
Simulations of Copper-1,10-Phenanthroline Complexes Binding the DNA 1.068
Functional rotation of the transporter AcrB: Insights into drug extrusion from simulations 1.041
Simulating Efflux Pumps: The Extrusion Mechanism of Substrates 1.040
CO escape from myoglobin with metadynamics simulations 1.020
Potent flaviviridae inhibitors: targeted finger domain of RdRp. 1.014
Potent flaviviridae inhibitors: targeted finger domain of RdRp 1.007
Functional Rotation of the Transporter AcrB: The Essentials of Peristaltic Motion and Subsequent Substrate Extrusion 977
A Molecular Approach to Ligand-Receptor Interaction 971
Mystery unveiled: benzimidazole docks different domains in Flaviviridae 944
Recognition of quinolone antibiotics by the multidrug efflux transporter MexB of Pseudomonas aeruginosa 918
Common recognition topology of mex transporters of Pseudomonas aeruginosa revealed by molecular modelling 899
Different approaches for the structural and functional characterization of a double variant hemoglobin (HbG-Philadelphia/Duarte) 871
Molecular rationale for the impairment of the MexAB-OprM efflux pump by a single mutation in MexA 863
Molecular insights into the Patched1 drug efflux inhibitory activity of panicein A hydroquinone: a computational study 846
Molecular Recognition Routes Of DNA By Anticancer Ligands: Mechanisms and Free Energies Explored Via Molecular Dynamics Simulations 845
Inhibition of the drug efflux activity of Ptch1 as a promising strategy to overcome chemotherapy resistance in cancer cells 837
Tripartite efflux pumps of the RND superfamily: what did we learn from computational studies? 834
Hb G-Philadelphia/Duarte (alfa68 Asn→Lys beta62 Ala→Pro) a new double variant structural and functional properties. 805
Understanding anticancer Drug-DNA interactions via molecular dynamics simulations 774
Molecular simulations reveal the molecular basis of diffusion through porins; and allow designing potent antibiotics 755
Totale 218.093
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Categoria #
all - tutte 315.260
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 315.260
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20213.402 0 0 0 0 0 0 0 0 0 0 1.762 1.640
2021/20229.283 1.032 1.023 421 557 814 757 571 351 545 1.021 1.070 1.121
2022/202315.310 997 1.592 1.526 1.199 1.209 1.725 761 1.465 1.069 1.146 1.709 912
2023/202422.342 706 852 1.390 3.483 2.262 3.866 1.826 1.618 843 1.177 2.201 2.118
2024/202572.889 7.777 10.130 6.048 38.794 2.552 2.601 3.298 211 342 278 366 492
2025/202610.838 623 400 1.412 926 810 619 3.467 512 841 1.203 25 0
Totale 251.116