UNICA IRIS Institutional Research Information System

RUGGERONE, PAOLO
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
EU - Europa 232.734
NA - Nord America 13.416
AS - Asia 5.281
SA - Sud America 951
Continente sconosciuto - Info sul continente non disponibili 451
AF - Africa 119
OC - Oceania 11
Totale 252.963
Salva come PNG Salva come JPEG
Nazione #
IT - Italia 229.501
US - Stati Uniti d'America 13.094
CN - Cina 1.938
SG - Singapore 1.828
UA - Ucraina 846
BR - Brasile 744
SE - Svezia 596
GB - Regno Unito 480
VN - Vietnam 480
DE - Germania 436
FI - Finlandia 358
FR - Francia 265
CA - Canada 226
HK - Hong Kong 220
IN - India 171
KR - Corea 121
BD - Bangladesh 103
AR - Argentina 70
IQ - Iraq 67
MX - Messico 43
PK - Pakistan 42
NL - Olanda 36
ID - Indonesia 34
JP - Giappone 34
TR - Turchia 34
ZA - Sudafrica 34
CO - Colombia 33
RU - Federazione Russa 33
EC - Ecuador 32
ES - Italia 31
TW - Taiwan 31
UZ - Uzbekistan 30
AT - Austria 29
BE - Belgio 23
PH - Filippine 23
PL - Polonia 22
VE - Venezuela 18
UY - Uruguay 16
JO - Giordania 15
MA - Marocco 14
PE - Perù 14
EG - Egitto 13
PY - Paraguay 13
SA - Arabia Saudita 13
EU - Europa 12
LT - Lituania 12
KE - Kenya 11
NP - Nepal 11
AU - Australia 10
AZ - Azerbaigian 10
GT - Guatemala 10
IR - Iran 10
CH - Svizzera 9
CL - Cile 9
CR - Costa Rica 9
TN - Tunisia 9
AE - Emirati Arabi Uniti 8
DZ - Algeria 8
JM - Giamaica 8
MY - Malesia 8
ET - Etiopia 7
RS - Serbia 7
TH - Thailandia 7
BH - Bahrain 6
DO - Repubblica Dominicana 6
IE - Irlanda 6
KG - Kirghizistan 6
LB - Libano 6
AO - Angola 5
HN - Honduras 5
MU - Mauritius 5
NG - Nigeria 5
PS - Palestinian Territory 5
MD - Moldavia 4
NO - Norvegia 4
PA - Panama 4
PT - Portogallo 4
RO - Romania 4
AM - Armenia 3
BG - Bulgaria 3
HR - Croazia 3
KW - Kuwait 3
KZ - Kazakistan 3
LU - Lussemburgo 3
SV - El Salvador 3
SY - Repubblica araba siriana 3
AL - Albania 2
BA - Bosnia-Erzegovina 2
BO - Bolivia 2
CZ - Repubblica Ceca 2
EE - Estonia 2
GR - Grecia 2
HU - Ungheria 2
IL - Israele 2
MT - Malta 2
NI - Nicaragua 2
OM - Oman 2
SN - Senegal 2
BB - Barbados 1
BS - Bahamas 1
Totale 252.504
Salva come PNG Salva come JPEG
Città #
Cagliari 220.984
Uta 7.714
Fairfield 1.313
Ashburn 1.145
Woodbridge 984
Singapore 921
San Jose 715
Chandler 664
Houston 654
Dallas 627
Boardman 564
Seattle 564
Ann Arbor 542
Wilmington 521
Jacksonville 471
Cambridge 455
Nyköping 361
Beijing 352
Dearborn 328
Council Bluffs 251
Los Angeles 214
Helsinki 212
Hefei 204
Hong Kong 194
Nanjing 169
Santa Clara 166
Munich 162
Lauterbourg 148
The Dalles 144
Boston 142
New York 132
Ho Chi Minh City 130
Mcallen 120
Seoul 117
Montréal 109
Shanghai 94
Hanoi 92
Buffalo 88
Milan 75
Dong Ket 66
Redwood City 63
San Diego 62
Guangzhou 59
São Paulo 58
Chicago 50
Columbus 50
Shenyang 50
Frankfurt am Main 49
Nanchang 48
Hebei 45
Changsha 43
London 42
Jiaxing 39
Orem 38
Redondo Beach 36
Tianjin 35
Fonni 31
Mountain View 31
Rome 31
Toronto 31
Washington 31
Baghdad 30
Phoenix 30
Verona 30
Falls Church 27
Brooklyn 26
New Taipei 26
Sassari 26
Tashkent 26
Zhengzhou 26
Chennai 25
Rio de Janeiro 24
Tokyo 24
Cedar Knolls 22
Orange 22
Jinan 21
Norwalk 20
Winnipeg 20
Brussels 19
Ottawa 19
Denver 18
Haiphong 18
Montreal 18
Belo Horizonte 17
Kunming 17
Nuremberg 17
Atlanta 16
Ningbo 16
Pune 16
San Francisco 16
Warsaw 16
Lahore 15
Da Nang 14
Johannesburg 14
Marseille 14
Norman 14
Vienna 14
Amman 13
Amsterdam 13
Stockholm 13
Totale 244.602
Salva come PNG Salva come JPEG
Nome #
Different molecular mechanisms of inhibition of bovine viral diarrhea virus and hepatitis C virus RNA-dependent RNA polymerases by a novel benzimidazole 36.867
Structure-Activity Relationship Study of Hydroxycoumarins and Mushroom Tyrosinase 4.720
A database of force-field parameters, dynamics, and properties of antimicrobial compounds 4.064
Multidrug efflux pumps and their inhibitors characterized by computational modeling 3.995
Insights into the homo-oligomerization properties of N-terminal coiled-coil domain of Ebola virus VP35 protein 3.284
Water-mediated interactions enable smooth substrate transport in a bacterial efflux pump 3.096
Molecular basis for the different interactions of congeneric substrates with the polyspecific transporter AcrB 3.085
Relevance of Ebola virus VP35 homo-dimerization on the type I interferon cascade inhibition 3.065
A novel dendrimeric peptide with antimicrobial properties: structure-function analysis of SB056 3.044
Computer simulations of the activity of RND efflux pumps 3.044
Molecular Rationale behind the Differential Substrate Specificity of Bacterial RND Multi-Drug Transporters 3.042
Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives 2.993
Computational modelling of efflux pumps and their inhibitors 2.942
Molecular Modeling of Multidrug Properties of Resistance Nodulation Division (RND) Transporters 2.931
Molecular Determinants of the Promiscuity of MexB and MexY Multidrug Transporters of Pseudomonas aeruginosa 2.909
A Novel Dendrimeric Peptide with Antimicrobial Properties: Structure-Function Analysis of SB056 2.875
Molecular Interactions of Cephalosporins with the Deep Binding Pocket of the RND Transporter AcrB 2.853
A New Critical Conformational Determinant of Multidrug Efflux by an MFS Transporter 2.851
Insights into Ebola VP35 oligomerization from molecular simulations 2.818
Molecular dynamics computer simulations of multidrug RND efflux pumps 2.786
Structural and functional characterization of a new double variant haemoglobin (HbG-Philadelphia/Duarte α268Asn→Lys β262Ala→Pro) 2.742
Computational study of correlated domain motions in the AcrB efflux transporter 2.724
AcrB drug-binding pocket substitution confers clinically relevant resistance and altered substrate specificity 2.681
Identification and characterization of carbapenem binding sites within the RND-transporter AcrB 2.639
Analysis of fast channel blockage: revealing substrate binding in the microsecond range 2.629
Molecular mechanism of MBX2319 inhibition of Escherichia coli AcrB multidrug efflux pump and comparison with other inhibitors 2.587
RND efflux pumps: structural information translated into function and inhibition mechanisms 2.480
Folding and Self-Assembly of the Pore-Forming Unit Tat-A of the Bacterial Twin-Arginine Translocase 2.355
Modeling Assembly of the Tata Pore Forming Complex using an Implicit Membrane Model 2.338
Binding and Transport of Carboxylated Drugs by the Multidrug Transporter AcrB 2.238
The challenge of intracellular antibiotic accumulation, a function of fluoroquinolone influx versus bacterial efflux 2.200
A kinetic Monte Carlo approach to investigate antibiotic translocation through bacterial porins 2.195
Folding and self-assembly of the TatA translocation pore based on a charge zipper mechanism 2.140
Mechanism of Inhibition By, and of Drug Resistance to, a Benzimidazole Inhibitor of the RNA-Dependent RNA Polymerase of Bovine Viral Diarrhoea Virus 2.136
Interaction of antibacterial compounds with RND efflux pumps in Pseudomonas aeruginosa 2.079
Molecular Mechanism of Viral Resistance to a Potent Non-nucleoside Inhibitor Unveiled by Molecular Simulations 2.046
Chlorpromazine and amitriptyline are substrates and inhibitors of the acrb multidrug efflux pump 2.014
Pathways to exit a receptor: a dynamical view of agonists - delta-opioids interaction 1.985
Molecular interactions of carbapenem antibiotics with the multidrug efflux transporter acrb of escherichia coli 1.969
Effects of Point Mutations on the Activity of AcrB 1.939
Molecular simulations reveal the mechanism and the determinants for ampicillin translocation through OmpF 1.914
Using Molecular Simulations to Screen for Antibiotics with Enhanced Permeation Properties through Bacterial Pores 1.912
Exploring Binding Properties of Agonists Interacting with a δ-Opioid Receptor 1.835
Heme proteins: the role of solvent on the dynamics of gates and portals 1.776
Point Mutation I261M Affects the Dynamics of BVDV and its Interaction with Benzimidazole Antiviral 227G 1.750
Investigating reaction pathways in rare events simulations of antibiotics diffusion through protein channels 1.749
Towards screening for antibiotics with enhanced permeation properties through bacterial porins 1.735
null 1.683
Structural and dynamical properties of the porins OmpF and OmpC: insights from molecular simulations 1.681
Recognition of imipenem and meropenem by the RND-transporter MexB studied by computer simulations 1.653
Bridging time and length scales: from macroscopic flux to molecular mechanism of antibiotics diffusion through porins 1.627
Cryo-EM structure and molecular dynamics analysis of the fluoroquinolone resistant mutant of the AcrB transporter from salmonella 1.599
Structural Determinants Of Antibiotic And betalactamase Diffusion Through Bacterial Porins 1.544
Perturbed structural dynamics underlie inhibition and altered efflux of the multidrug resistance pump AcrB 1.523
Structural determinants of antibiotic translocations in OMPF 1.522
Impact of corpus callosum integrity on functional interhemispheric connectivity and cognition in healthy subjects 1.487
Mechanism of inhibition by, and drug resistance to, a benzimidazole inhibitor of the Rna-dependent-Rna-polymerase of Bovine Viral Diarrhoea virus 1.456
A framework for dissecting affinities of multidrug efflux transporter AcrB to fluoroquinolones 1.455
Predictive rules of efflux inhibition and avoidance in Pseudomonas aeruginosa 1.433
Role of water during the extrusion of substrates by the efflux transporter AcrB 1.404
Advanced computational methods in molecular medicine 1.402
Simulating bacterial efflux: how molecular features affect functional rotation 1.379
null 1.359
Structural analysis of hemoglobins and myoglobins using MD simulations 1.357
Meropenem vs. Imipenem interacting with MexB: structural and dynamical determinants of the efflux action on two substrates 1.301
Bacterial efflux transporters’ polyspecificity – a gift and a curse? 1.272
Pathways to Exit a Receptor: Agonists and Delta-Oppioid Studied via Computer Simulations 1.256
Drug design: Insights from atomistic simulations 1.249
First-principles prediction of structure, energetics, formation enthalpy, elastic constants, polarization, and piezoelectric constants of AlN, GaN, and InN: Comparison of local and gradient-corrected density-functional theory 1.217
Structural determinants of antibiotic and β-lactamase diffusion through bacterial porins 1.209
Breathing motions of a respiratory protein revealed by molecular dynamics simulation 1.199
Erratum: Role of water during the extrusion of substrates by the efflux transporter AcrB (Journal of Physical Chemistry B (2011) 115 (8278-8287) DOI: 10.1021/jp200996x) 1.190
Effects of the F610A mutation on substrate extrusion in the AcrB transporter: explanation and rationale by molecular dynamics simulations 1.178
Molecular simulations of SSTR2 dynamics and interaction with ligands 1.147
Screening for antibiotics with enhanced permeation properties: proof of concept using molecular simulations 1.146
Functional Rotation of the Transporter AcrB: Insights into Drug Extrusion from Simulations 1.143
Evidences of Xenon-Induced Structural Changes in the Active Site of Cyano-MetMyoglobins: A 1H NMR Study 1.129
The Biophysics Of Antibiotics Translocation Through OmpF Revealed By Computer Simulations 1.125
AB-DB: Force-Field parameters, MD trajectories, QM-based data, and Descriptors of Antimicrobials 1.125
Molecular motions in drug design: the coming age of the metadynamics method 1.097
Simulations of Copper-1,10-Phenanthroline Complexes Binding the DNA 1.087
Functional rotation of the transporter AcrB: Insights into drug extrusion from simulations 1.049
Simulating Efflux Pumps: The Extrusion Mechanism of Substrates 1.047
CO escape from myoglobin with metadynamics simulations 1.028
Potent flaviviridae inhibitors: targeted finger domain of RdRp. 1.022
Potent flaviviridae inhibitors: targeted finger domain of RdRp 1.014
Functional Rotation of the Transporter AcrB: The Essentials of Peristaltic Motion and Subsequent Substrate Extrusion 984
A Molecular Approach to Ligand-Receptor Interaction 981
Mystery unveiled: benzimidazole docks different domains in Flaviviridae 948
Recognition of quinolone antibiotics by the multidrug efflux transporter MexB of Pseudomonas aeruginosa 929
Common recognition topology of mex transporters of Pseudomonas aeruginosa revealed by molecular modelling 921
Different approaches for the structural and functional characterization of a double variant hemoglobin (HbG-Philadelphia/Duarte) 878
Molecular rationale for the impairment of the MexAB-OprM efflux pump by a single mutation in MexA 870
Tripartite efflux pumps of the RND superfamily: what did we learn from computational studies? 859
Molecular insights into the Patched1 drug efflux inhibitory activity of panicein A hydroquinone: a computational study 856
Molecular Recognition Routes Of DNA By Anticancer Ligands: Mechanisms and Free Energies Explored Via Molecular Dynamics Simulations 851
Inhibition of the drug efflux activity of Ptch1 as a promising strategy to overcome chemotherapy resistance in cancer cells 849
Hb G-Philadelphia/Duarte (alfa68 Asn→Lys beta62 Ala→Pro) a new double variant structural and functional properties. 808
Molecular simulations reveal the molecular basis of diffusion through porins; and allow designing potent antibiotics 783
Understanding anticancer Drug-DNA interactions via molecular dynamics simulations 781
Totale 219.143
Salva come PNG Salva come JPEG
Categoria #
all - tutte 323.962
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 323.962
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20228.251 0 1.023 421 557 814 757 571 351 545 1.021 1.070 1.121
2022/202315.310 997 1.592 1.526 1.199 1.209 1.725 761 1.465 1.069 1.146 1.709 912
2023/202422.342 706 852 1.390 3.483 2.262 3.866 1.826 1.618 843 1.177 2.201 2.118
2024/202572.889 7.777 10.130 6.048 38.794 2.552 2.601 3.298 211 342 278 366 492
2025/202612.056 623 400 1.412 926 810 619 3.467 512 841 1.203 713 530
2026/2027629 182 447 0 0 0 0 0 0 0 0 0 0
Totale 252.963