A naturally occurring compound with strong antifungal activity was isolated from the flavedo tissue of "Star Ruby" grapefruits (Citrus paradisi) and identified as 7-geranoxycoumarin. A high yield strategy for its synthesis was found and its antifungal activity against Penicillium italicum and P. digitatum assessed by in vivo and in vitro test. (C) 1998 Elsevier Science Ltd. All rights reserved.
Synthesis and inhibitory activity of 7-geranoxycoumarine against Penicillum species in citrus fruit
ANGIONI, ALBERTO;PIRISI, FILIPPO MARIA;
1998-01-01
Abstract
A naturally occurring compound with strong antifungal activity was isolated from the flavedo tissue of "Star Ruby" grapefruits (Citrus paradisi) and identified as 7-geranoxycoumarin. A high yield strategy for its synthesis was found and its antifungal activity against Penicillium italicum and P. digitatum assessed by in vivo and in vitro test. (C) 1998 Elsevier Science Ltd. All rights reserved.
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