ESPOSITO, FRANCESCA
 Distribuzione geografica
Continente #
EU - Europa 203.029
NA - Nord America 6.629
AS - Asia 1.025
AF - Africa 17
Continente sconosciuto - Info sul continente non disponibili 10
OC - Oceania 5
SA - Sud America 5
Totale 210.720
Nazione #
IT - Italia 201.293
US - Stati Uniti d'America 6.580
CN - Cina 671
UA - Ucraina 581
SE - Svezia 543
DE - Germania 226
FI - Finlandia 149
SG - Singapore 132
GB - Regno Unito 118
VN - Vietnam 71
CA - Canada 44
FR - Francia 44
IN - India 41
KR - Corea 24
HK - Hong Kong 18
TR - Turchia 15
IR - Iran 12
BE - Belgio 11
PK - Pakistan 11
PL - Polonia 11
EU - Europa 8
ES - Italia 7
JP - Giappone 7
NL - Olanda 7
CZ - Repubblica Ceca 6
IQ - Iraq 6
ID - Indonesia 5
RU - Federazione Russa 5
ZA - Sudafrica 5
AU - Australia 4
CH - Svizzera 4
LV - Lettonia 4
NO - Norvegia 4
TW - Taiwan 4
CL - Cile 3
DZ - Algeria 3
EG - Egitto 3
GR - Grecia 3
IE - Irlanda 3
MX - Messico 3
TN - Tunisia 3
A1 - Anonimo 2
AT - Austria 2
HR - Croazia 2
IL - Israele 2
MU - Mauritius 2
PT - Portogallo 2
SA - Arabia Saudita 2
TH - Thailandia 2
AE - Emirati Arabi Uniti 1
BR - Brasile 1
CO - Colombia 1
CR - Costa Rica 1
DO - Repubblica Dominicana 1
HU - Ungheria 1
LU - Lussemburgo 1
MA - Marocco 1
NZ - Nuova Zelanda 1
RO - Romania 1
SI - Slovenia 1
TJ - Tagikistan 1
Totale 210.720
Città #
Cagliari 200.736
Fairfield 825
Woodbridge 764
Chandler 541
Ashburn 450
Nyköping 418
Houston 416
Seattle 360
Wilmington 359
Ann Arbor 352
Cambridge 304
Jacksonville 286
New York 217
Dearborn 198
Boardman 124
Shanghai 119
Nanjing 117
Boston 91
Beijing 88
Dong Ket 69
Redwood City 64
Helsinki 62
Singapore 53
San Diego 48
Herndon 40
Nanchang 33
Rome 32
Mountain View 31
Guangzhou 28
Shenyang 28
Milan 27
Changsha 24
Hebei 24
Los Angeles 23
Toronto 22
Seoul 21
Jiaxing 19
Orange 19
Atlanta 17
Ottawa 17
Norwalk 16
Sassari 16
Tianjin 16
Washington 15
Hong Kong 14
Jinan 14
Verona 14
Wuhan 14
London 13
Pune 13
Hangzhou 12
Brussels 11
Istanbul 11
Kunming 11
Phoenix 11
Falls Church 9
Napoli 9
Auburn Hills 8
Paris 8
Warsaw 8
Zhengzhou 8
Hefei 7
Redmond 7
Gujranwala 6
Jinhua 6
Menlo Park 6
Millbury 6
Mumbai 6
Ningbo 6
Siracusa 6
Chicago 5
Frankfurt am Main 5
Indiana 5
Kilburn 5
Quartu Sant'Elena 5
Antea 4
Bari 4
Carbonia 4
Chiswick 4
Cosenza 4
Hyderabad 4
Jakarta 4
Munich 4
Nanning 4
Oslo 4
Padova 4
Quartu Sant'elena 4
Rockville 4
Serramanna 4
Tappahannock 4
Trieste 4
Villanovafranca 4
Wuxi 4
Acton 3
Bad Bellingen 3
Brno 3
Bultei 3
Chengdu 3
Edinburgh 3
Greensboro 3
Totale 207.891
Nome #
(3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro- 1H -indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase 5.339
Design, synthesis, and biological evaluation of 1,3-diarylpropenones as dual inhibitors of HIV-1 reverse transcriptase 4.166
Ribonuclease H/DNA polymerase HIV-1 reverse transcriptase dual inhibitor: mechanistic studies on the allosteric mode of action of isatin-based compound RMNC6 4.044
Biological activities of aerial parts extracts of Euphorbia characias 4.027
Euphorbia characias latex: Micromorphology of rubber particles and rubber transferase activity 3.427
Identification of Myricetin as Ebolavirus VP35-dsRNA interaction inhibitor through a novel fluorescence-based assay 3.318
Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 Reverse transcriptase-associated RNase H and RDDP functions 3.200
Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach 3.173
Sennoside A, derived from the traditional chinese medicine plant Rheum L., is a new dual HIV-1 inhibitor effective on HIV-1 replication 3.110
Dual HIV-1 reverse transcriptase and integrase inhibitors from Limonium morisianum Arrigoni, an endemic species of Sardinia (Italy) 3.067
Design and synthesis of new isatin derivatives as HIV-1 reverse transcriptase associated ribonuclease H inhibitors 3.019
Studies on Cycloheptathiophene-3-carboxamide Derivatives as Allosteric HIV-1 Ribonuclease H Inhibitors 2.990
Multi-target activity of Hemidesmus indicus decoction against innovative HIV-1 drug targets and characterization of Lupeol mode of action 2.975
New insights into the operative network of FaEO, an enone oxidoreductase from Fragaria x ananassa Duch 2.797
Prenylated phloroglucinols from Hypericum scruglii, an endemic species of Sardinia (Italy), as new dual HIV-1 inhibitors effective on HIV-1 replication 2.750
null 2.719
S-layer proteins as a source of carotenoids: Isolation of the carotenoid cofactor deinoxanthin from its S-layer protein DR_2577 2.719
Inhibition of HIV-1 reverse transcriptase dimerization by small molecules 2.713
Purification and characterization of DR_2577 (SlpA) a major S-layer protein from Deinococcus radiodurans 2.709
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) shed light on the mechanism of action of a new Ribonuclease H/ DNA polymerase RT dual inhibitor 2.700
Onopordum illyricum L., a Mediterranean plant, as a source of anti HIV-1 compounds 2.677
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) enlighten the mechanism of action of a new Ribonuclease H/DNA polymerase RT dual inhibitor 2.667
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Single Site Dual Inhibitors of HIV-1 RT 2.665
Preliminary study of endemic plants of Sardinia as a source of new antiviral agents 2.651
Chelation motifs affecting metal-dependent viral enzymes: N′-acylhydrazone ligands as dual target inhibitors of HIV-1 Integrase and Reverse Transcriptase Ribonuclease H domain 2.631
From the traditional Chinese medicine plant Schisandra chinensis new scaffolds effective on HIV-1 reverse transcriptase resistant to non-nucleoside inhibitors 2.598
Hypericum hircinum L. components as new single-molecule inhibitors of both HIV-1 reverse transcriptase-associated DNA polymerase and ribonuclease H activities 2.586
RhVI1 is a membrane-anchored vacuolar invertase highly expressed in Rosa hybrida L. petals 2.508
Natural Product Kuwanon-L Inhibits HIV-1 Replication through Multiple Target Binding 2.502
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Dual Inhibitors of HIV-1 RT. 2.500
On the S-layer of Thermus thermophilus and the assembling of its main protein SIpA 2.493
Structure-guided approach identifies a novel class of HIV-1 Ribonuclease H inhibitors: Binding mode insights through magnesium complexation and site-directed mutagenesis studies 2.464
Chromenone derivatives as a versatile scaffold with dual mode of inhibition of HIV-1 reverse transcriptase-associated Ribonuclease H function and integrase activity 2.456
New insights into the interaction between pyrrolyl diketoacids and HIV-1 integrase active site and comparison with RNase H 2.444
Identification of a novel HERV-K(HML10): comprehensive characterization and comparative analysis in non-human primates provide insights about HML10 proviruses structure and diffusion 2.284
3-[2-(4-aryl-1,3-thiazol-2-yl)hydrazin-1-ylidene]-1H-indol-2-ones as new potential dual inhibitors of polimerase and ribonuclease HIV-1 RT associated function 2.243
Chalcones as novel dual inhibitors of HIV-1 reverse transcriptase 2.235
An efficient route to novel uracil-based drug-like molecules 2.187
Structure-Activity Relationship of Pyrrolyl Diketo Acid Derivatives as Dual Inhibitors of HIV-1 Integrase and Reverse Transcriptase Ribonuclease H Domain 2.150
Validation of a computed radiography device to monitor the HIV-1 RNase H activity 2.148
A Luciferase Reporter Gene Assay to Measure Ebola Virus Viral Protein 35–Associated Inhibition of Double-Stranded RNA–Stimulated, Retinoic Acid–Inducible Gene 1–Mediated Induction of Interferon β 2.097
Improvement of the activity of the anti-HIV-1 integrase aptamer T30175 by introducing a modified thymidine into the loops 2.061
Exploring new scaffolds for the inibition of the Ribonuclease H function of RT HIV-1 2.058
Investigation on the sucrose binding pocket of HIV-1 Integrase by molecular dynamics and synergy experiments 2.028
Inhibitory effect of 2,3,5,6-tetrafluoro-4-[4-(Aryl)-1H-1,2,3-triazol-1-yl]benzenesulfonamide derivatives on HIV reverse transcriptase associated rnase H activities 2.016
Mutagenic study on HIV-1 reverse transcriptase to explore the mechanism of action of HIV-1 reverse transcriptase dual inhibitors 2.012
Development and identification of a novel anti-HIV-1 peptide derived by modification of the N-terminal domain of HIV-1 integrase 1.992
Design and synthesis of new Isatin derivatives as HIV-1 Reverse Transcriptase associated Ribonuclease H inhibitors twenty-fourth 1.953
Inhibition of HIV-1 reverse transcriptase associated activities by the hydroalcoholic extract of Casimiroa edulis seeds 1.920
2-(Arylamino)-6-(trifluoromethyl)nicotinic Acid Derivatives: New HIV-1 RT Dual Inhibitors Active on Viral Replication 1.867
Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach 1.865
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases 1.864
null 1.851
Kuwanon-L as a new allosteric HIV-1 integrase inhibitor: molecular modeling and biological evaluation 1.847
Discovery of dihydroxyindole-2-carboxylic acid derivatives as dual allosteric HIV-1 Integrase and Reverse Transcriptase associated Ribonuclease H inhibitors 1.837
null 1.820
Isatin derivatives as new scaffolds for HIV-1 reverse transcriptase associated RNase H and RDDP dual inhibitors 1.811
6-(1-Benzyl-1H-pyrrol-2-yl)-2,4-dioxo-5-hexenoic acids as dual inhibitors of recombinant HIV-1 integrase and ribonuclease H, synthesized by a parallel synthesis approach 1.802
Targeting HIV-1 RNase H: N'-(2-Hydroxy-benzylidene)-3,4,5-Trihydroxybenzoylhydrazone as Selective Inhibitor Active against NNRTIs-Resistant Variants 1.796
Design of new inhibitors of the HIV-1 Reverse Transcriptase associated Ribonuclease H function: a synthetic approach 1.716
Design, synthesis and biolgical activity evaluation of new HIV-1 reverse transcriptase dual inhibitors 1.707
Identification of new scaffolds for the inhibition of HIV-1 Reverse Transcriptase associated Ribonuclease H function by means of shape based similarity screening 1.600
Pyrrolyl Pyrazoles as Non-Diketo Acid Inhibitors of the HIV-1 Ribonuclease H Function of Reverse Transcriptase 1.600
HIV-1 inhibiting activity of the essential oil of Ridolfia segetum and Oenanthe crocata 1.560
Inhibition of HIV-1 Ribonuclease H activity by novel frangula-emodine derivatives 1.551
SITE DIRECT MUTAGENESIS AND KINETIC STUDIES TO EXPLORE THE MECHANISM OF ACTION OF ISATIN DERIVATIVES AS HIV-1 REVERSE TRANSCRIPTASE DUAL INHIBITORS 1.539
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and Ribonuclease H activities effective also on non-nucleoside resistant RTs 1.506
New anthraquinone derivatives as inhibitors of the HIV-1 reverse transcriptase-associated ribonuclease H function 1.494
Exploring new scaffolds for the inhibition of the Ribonuclease H function of RT HIV-1 1.485
dsRNA binding characterization of full length recombinant wild type and mutants Zaire ebolavirus VP35 1.481
The traditional Chinese medicine plant Schisandra Chinensis as source of new HIV-1 reverse transcriptase inhibitor scaffolds effective also on non-nucleoside resistant reverse transcriptases 1.480
Design, synthesis and biological activity evaluation of new HIV-1 reverse transcriptase dual inhibitors 1.467
Scaffold hopping and optimisation of 3’,4’-dihydroxyphenyl- containing thienopyrimidinones: synthesis of quinazolinone derivatives as novel allosteric inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H 1.442
Effects of new quinizarin derivatives on both HCV NS5B RNA polymerase and HIV-1 reverse transcriptase associated ribonuclease H activities 1.414
Synthesis and biological evaluation of new dual inhibitors of HIV-1 associated functions 1.355
From classic to innovative approaches in HIV-1 infection treatment 1.349
Anti-HIV-1 activity of compounds isolated from Hypericum hircinum. 1.327
Identification of highly conserved residues involved in inhibition of HIV-1 RNase H function by Diketo acid derivatives 1.323
Development of a Raltegravir-based Photoaffinity-Labeled Probe for Human Immunodeficiency Virus-1 Integrase Capture 1.290
Can the ever-promising target HIV reverse transcriptase-associated RNase H become a success story for drug development? 1.279
A Homogeneous Time Resolved Fluorescence (HTRF) method for the evaluation of HIV-1 integrase dimerization, enzyme reactions and interaction with LEDGF/p75 1.272
Effect of Non-nucleoside Reverse Transcriptase Inhibitors on the HIV-1 Reverse Transcriptase Associated Ribonuclease-H Activity 1.254
null 1.214
Shape based computer aided similarity screening: a valid tool in the discovery of new scaffolds for the inhibition of HIV-1 reverse transcriptase associated ribonuclease H function 1.182
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase (RT) -associated DNA polymerase and Ribonuclease H (RNase H) activities effective also on the RNase H activity of non-nucleoside resistant RTs 1.178
Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen 1.171
Probing the importance of the g-quadruplex grooves for the activity of the anti-hiv-integrase aptamer t30923 1.156
HIV-1 reverse transcriptase and K562 cell replication inhibition by Ridolfia segetum (L.) Moris essential oil 1.009
A combined shape-, 2D-fingerprint-and pharmacophore-based virtual screening for the identification of dual inhibitors targeting HIV-1 reverse transcriptase. 930
Past and future. Current drugs targeting HIV-1 integrase and reverse transcriptase-associated ribonuclease H activity: single and dual active site inhibitors 839
Development of 3-hydroxyquinolein-2(1H)-ones as inhibitors of HIV-1 integrase and ribonuclease H function of reverse transcriptase 837
Natural Compounds Inhibit SARS-CoV-2 nsp13 Unwinding and ATPase Enzyme Activities 830
Exploring new scaffolds for the dual inhibition of HIV-1 RT polymerase and ribonuclease associated functions 806
A combined cell based and site directed mutagenesis approach defines highly conserved residues involved in the selective inhibition of the HIV-1 ribonuclease H function by diketoacid derivatives 796
In Vitro Anti-HIV-1 Reverse Transcriptase and Integrase Properties of Punica granatum L. Leaves, Bark, and Peel Extracts and Their Main Compounds 752
Development of a series of 3-hydroxyquinolin-2(1H)-ones as selective inhibitors of HIV-1 reverse transcriptase associated RNase H activity 713
Hemidesmus Indicus: Dall’antica Tradizone Ayurvedica Alle Potenzilità Anti-HIV1 E Nei Disordini Multifattoriali 669
HIV-1 Reverse Transcriptase still remains a new drug target: Structure, Function, Classical inhibitors and new inhibitors with innovative mechanism of action 661
Quinolinonyl Non-Diketo Acid Derivatives as Inhibitors of HIV-1 Ribonuclease H and Polymerase Functions of Reverse Transcriptase 645
Development of a series of 3-hydroxyquinolein-2(1H)-ones as selective inhibitors of HIV-1 reverse transcriptase associated RNase H activity 634
Totale 200.061
Categoria #
all - tutte 242.263
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 242.263


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202037.050 1.882 1.587 302 587 12.748 9.736 5.182 977 652 1.028 791 1.578
2020/202154.305 1.646 1.809 2.383 14.910 10.176 5.582 4.220 3.507 1.363 3.344 3.907 1.458
2021/202213.416 1.338 1.020 642 772 1.064 1.094 720 579 1.260 1.273 1.812 1.842
2022/202321.107 1.698 2.901 2.540 2.044 1.399 2.491 1.086 1.683 1.162 1.243 1.870 990
2023/202420.613 905 749 1.251 1.736 2.153 3.614 2.934 1.418 986 1.195 1.758 1.914
2024/20254.442 4.442 0 0 0 0 0 0 0 0 0 0 0
Totale 211.188