UNICA IRIS Institutional Research Information System

ESPOSITO, FRANCESCA
 Distribuzione geografica
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Continente #
EU - Europa 245.623
NA - Nord America 10.434
AS - Asia 4.668
SA - Sud America 726
AF - Africa 168
Continente sconosciuto - Info sul continente non disponibili 10
OC - Oceania 7
Totale 261.636
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Nazione #
IT - Italia 243.056
US - Stati Uniti d'America 10.280
SG - Singapore 1.796
CN - Cina 1.636
SE - Svezia 633
UA - Ucraina 598
BR - Brasile 545
VN - Vietnam 401
DE - Germania 329
FI - Finlandia 301
FR - Francia 226
GB - Regno Unito 198
IN - India 140
HK - Hong Kong 138
CA - Canada 99
KR - Corea 92
AR - Argentina 79
BD - Bangladesh 75
MA - Marocco 58
NL - Olanda 56
TR - Turchia 52
IQ - Iraq 50
JP - Giappone 50
ZA - Sudafrica 42
PK - Pakistan 41
PL - Polonia 38
AT - Austria 37
MX - Messico 33
EC - Ecuador 31
ES - Italia 28
ID - Indonesia 27
RU - Federazione Russa 23
SA - Arabia Saudita 23
BE - Belgio 21
UZ - Uzbekistan 21
VE - Venezuela 20
CO - Colombia 18
TN - Tunisia 17
IE - Irlanda 14
IR - Iran 14
KE - Kenya 13
PH - Filippine 13
EG - Egitto 11
TW - Taiwan 11
AZ - Azerbaigian 10
AE - Emirati Arabi Uniti 9
CZ - Repubblica Ceca 9
DZ - Algeria 9
JO - Giordania 9
EU - Europa 8
NP - Nepal 8
BO - Bolivia 7
GE - Georgia 7
UY - Uruguay 7
CL - Cile 6
IL - Israele 6
LV - Lettonia 6
MY - Malesia 6
NO - Norvegia 6
PE - Perù 6
AL - Albania 5
AU - Australia 5
CH - Svizzera 5
CR - Costa Rica 5
KG - Kirghizistan 5
LB - Libano 5
PT - Portogallo 5
ET - Etiopia 4
GR - Grecia 4
HU - Ungheria 4
KZ - Kazakistan 4
LT - Lituania 4
PY - Paraguay 4
RO - Romania 4
DK - Danimarca 3
DO - Repubblica Dominicana 3
LU - Lussemburgo 3
MU - Mauritius 3
NI - Nicaragua 3
SV - El Salvador 3
TH - Thailandia 3
A1 - Anonimo 2
AM - Armenia 2
CI - Costa d'Avorio 2
HR - Croazia 2
JM - Giamaica 2
KH - Cambogia 2
NZ - Nuova Zelanda 2
OM - Oman 2
PS - Palestinian Territory 2
SR - Suriname 2
SY - Repubblica araba siriana 2
TT - Trinidad e Tobago 2
AO - Angola 1
BB - Barbados 1
BG - Bulgaria 1
BJ - Benin 1
BN - Brunei Darussalam 1
BW - Botswana 1
CG - Congo 1
Totale 261.618
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Città #
Cagliari 237.129
Uta 5.175
Ashburn 962
Singapore 952
Fairfield 825
Woodbridge 764
San Jose 631
Dallas 543
Chandler 541
Boardman 443
Houston 427
Nyköping 418
Seattle 369
Wilmington 363
Ann Arbor 352
Beijing 333
Cambridge 305
Jacksonville 290
New York 276
Council Bluffs 199
Dearborn 198
Los Angeles 194
Helsinki 184
Santa Clara 149
Shanghai 131
The Dalles 128
Lauterbourg 124
Hong Kong 123
Nanjing 119
Ho Chi Minh City 109
Boston 108
Hefei 104
Seoul 81
Hanoi 76
Dong Ket 69
Buffalo 65
Redwood City 64
Rome 61
Munich 55
San Diego 50
Milan 45
Redondo Beach 41
Guangzhou 40
Herndon 40
São Paulo 40
Tokyo 40
Casablanca 39
Nanchang 36
Atlanta 35
Chicago 35
Changsha 32
Warsaw 32
Amsterdam 31
Mountain View 31
Shenyang 31
Tianjin 31
London 29
Orem 28
Toronto 28
Phoenix 27
Columbus 26
Rio de Janeiro 25
Frankfurt am Main 24
Hebei 24
Montreal 23
Vienna 23
Baghdad 21
Jiaxing 21
Chennai 20
Orange 20
Brooklyn 19
Istanbul 19
Tashkent 19
Washington 19
Hangzhou 18
Johannesburg 18
Norwalk 17
Ottawa 17
Shenzhen 17
Da Nang 16
Guayaquil 16
Mumbai 16
Sassari 16
Turku 16
Jinan 15
Lappeenranta 15
Nuremberg 15
Pune 15
San Francisco 15
Verona 15
Wuhan 15
Stockholm 14
Brussels 13
Denver 13
Kunming 13
Lahore 13
Naples 13
Zhengzhou 13
Contagem 11
Dhaka 11
Totale 254.869
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Nome #
(3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro- 1H -indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase 14.730
Design, synthesis, and biological evaluation of 1,3-diarylpropenones as dual inhibitors of HIV-1 reverse transcriptase 4.533
Biological activities of aerial parts extracts of Euphorbia characias 4.445
Ribonuclease H/DNA polymerase HIV-1 reverse transcriptase dual inhibitor: mechanistic studies on the allosteric mode of action of isatin-based compound RMNC6 4.332
Identification of Myricetin as Ebolavirus VP35-dsRNA interaction inhibitor through a novel fluorescence-based assay 3.757
Euphorbia characias latex: Micromorphology of rubber particles and rubber transferase activity 3.680
Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 Reverse transcriptase-associated RNase H and RDDP functions 3.519
Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach 3.492
Dual HIV-1 reverse transcriptase and integrase inhibitors from Limonium morisianum Arrigoni, an endemic species of Sardinia (Italy) 3.449
Sennoside A, derived from the traditional chinese medicine plant Rheum L., is a new dual HIV-1 inhibitor effective on HIV-1 replication 3.435
Design and synthesis of new isatin derivatives as HIV-1 reverse transcriptase associated ribonuclease H inhibitors 3.354
Studies on Cycloheptathiophene-3-carboxamide Derivatives as Allosteric HIV-1 Ribonuclease H Inhibitors 3.313
Multi-target activity of Hemidesmus indicus decoction against innovative HIV-1 drug targets and characterization of Lupeol mode of action 3.300
New insights into the operative network of FaEO, an enone oxidoreductase from Fragaria x ananassa Duch 3.114
S-layer proteins as a source of carotenoids: Isolation of the carotenoid cofactor deinoxanthin from its S-layer protein DR_2577 3.094
Inhibition of HIV-1 reverse transcriptase dimerization by small molecules 3.081
Prenylated phloroglucinols from Hypericum scruglii, an endemic species of Sardinia (Italy), as new dual HIV-1 inhibitors effective on HIV-1 replication 3.053
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Dual Inhibitors of HIV-1 RT. 3.043
Onopordum illyricum L., a Mediterranean plant, as a source of anti HIV-1 compounds 3.006
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) enlighten the mechanism of action of a new Ribonuclease H/DNA polymerase RT dual inhibitor 2.981
Purification and characterization of DR_2577 (SlpA) a major S-layer protein from Deinococcus radiodurans 2.969
Preliminary study of endemic plants of Sardinia as a source of new antiviral agents 2.935
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Single Site Dual Inhibitors of HIV-1 RT 2.933
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) shed light on the mechanism of action of a new Ribonuclease H/ DNA polymerase RT dual inhibitor 2.923
From the traditional Chinese medicine plant Schisandra chinensis new scaffolds effective on HIV-1 reverse transcriptase resistant to non-nucleoside inhibitors 2.921
Structure-guided approach identifies a novel class of HIV-1 Ribonuclease H inhibitors: Binding mode insights through magnesium complexation and site-directed mutagenesis studies 2.888
Chelation motifs affecting metal-dependent viral enzymes: N′-acylhydrazone ligands as dual target inhibitors of HIV-1 Integrase and Reverse Transcriptase Ribonuclease H domain 2.879
Hypericum hircinum L. components as new single-molecule inhibitors of both HIV-1 reverse transcriptase-associated DNA polymerase and ribonuclease H activities 2.876
On the S-layer of Thermus thermophilus and the assembling of its main protein SIpA 2.849
Natural Product Kuwanon-L Inhibits HIV-1 Replication through Multiple Target Binding 2.831
RhVI1 is a membrane-anchored vacuolar invertase highly expressed in Rosa hybrida L. petals 2.818
Mutagenic study on HIV-1 reverse transcriptase to explore the mechanism of action of HIV-1 reverse transcriptase dual inhibitors 2.776
Chromenone derivatives as a versatile scaffold with dual mode of inhibition of HIV-1 reverse transcriptase-associated Ribonuclease H function and integrase activity 2.736
null 2.719
New insights into the interaction between pyrrolyl diketoacids and HIV-1 integrase active site and comparison with RNase H 2.713
3-[2-(4-aryl-1,3-thiazol-2-yl)hydrazin-1-ylidene]-1H-indol-2-ones as new potential dual inhibitors of polimerase and ribonuclease HIV-1 RT associated function 2.621
Identification of a novel HERV-K(HML10): comprehensive characterization and comparative analysis in non-human primates provide insights about HML10 proviruses structure and diffusion 2.577
Chalcones as novel dual inhibitors of HIV-1 reverse transcriptase 2.466
Structure-Activity Relationship of Pyrrolyl Diketo Acid Derivatives as Dual Inhibitors of HIV-1 Integrase and Reverse Transcriptase Ribonuclease H Domain 2.432
Inhibition of HIV-1 reverse transcriptase associated activities by the hydroalcoholic extract of Casimiroa edulis seeds 2.426
Validation of a computed radiography device to monitor the HIV-1 RNase H activity 2.410
An efficient route to novel uracil-based drug-like molecules 2.372
Inhibitory effect of 2,3,5,6-tetrafluoro-4-[4-(Aryl)-1H-1,2,3-triazol-1-yl]benzenesulfonamide derivatives on HIV reverse transcriptase associated rnase H activities 2.364
Improvement of the activity of the anti-HIV-1 integrase aptamer T30175 by introducing a modified thymidine into the loops 2.347
A Luciferase Reporter Gene Assay to Measure Ebola Virus Viral Protein 35–Associated Inhibition of Double-Stranded RNA–Stimulated, Retinoic Acid–Inducible Gene 1–Mediated Induction of Interferon β 2.317
Exploring new scaffolds for the inibition of the Ribonuclease H function of RT HIV-1 2.273
2-(Arylamino)-6-(trifluoromethyl)nicotinic Acid Derivatives: New HIV-1 RT Dual Inhibitors Active on Viral Replication 2.262
Development and identification of a novel anti-HIV-1 peptide derived by modification of the N-terminal domain of HIV-1 integrase 2.224
Investigation on the sucrose binding pocket of HIV-1 Integrase by molecular dynamics and synergy experiments 2.221
Design and synthesis of new Isatin derivatives as HIV-1 Reverse Transcriptase associated Ribonuclease H inhibitors twenty-fourth 2.157
Isatin derivatives as new scaffolds for HIV-1 reverse transcriptase associated RNase H and RDDP dual inhibitors 2.151
Discovery of dihydroxyindole-2-carboxylic acid derivatives as dual allosteric HIV-1 Integrase and Reverse Transcriptase associated Ribonuclease H inhibitors 2.135
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases 2.113
Targeting HIV-1 RNase H: N'-(2-Hydroxy-benzylidene)-3,4,5-Trihydroxybenzoylhydrazone as Selective Inhibitor Active against NNRTIs-Resistant Variants 2.112
Design, synthesis and biolgical activity evaluation of new HIV-1 reverse transcriptase dual inhibitors 2.091
Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach 2.084
Kuwanon-L as a new allosteric HIV-1 integrase inhibitor: molecular modeling and biological evaluation 2.079
6-(1-Benzyl-1H-pyrrol-2-yl)-2,4-dioxo-5-hexenoic acids as dual inhibitors of recombinant HIV-1 integrase and ribonuclease H, synthesized by a parallel synthesis approach 2.045
Design, synthesis and biological activity evaluation of new HIV-1 reverse transcriptase dual inhibitors 1.980
DHFR Inhibitors Display a Pleiotropic Anti-Viral Activity against SARS-CoV-2: Insights into the Mechanisms of Action 1.890
Design of new inhibitors of the HIV-1 Reverse Transcriptase associated Ribonuclease H function: a synthetic approach 1.889
Pyrrolyl Pyrazoles as Non-Diketo Acid Inhibitors of the HIV-1 Ribonuclease H Function of Reverse Transcriptase 1.881
null 1.851
Scaffold hopping and optimisation of 3’,4’-dihydroxyphenyl- containing thienopyrimidinones: synthesis of quinazolinone derivatives as novel allosteric inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H 1.835
null 1.820
Identification of new scaffolds for the inhibition of HIV-1 Reverse Transcriptase associated Ribonuclease H function by means of shape based similarity screening 1.817
SITE DIRECT MUTAGENESIS AND KINETIC STUDIES TO EXPLORE THE MECHANISM OF ACTION OF ISATIN DERIVATIVES AS HIV-1 REVERSE TRANSCRIPTASE DUAL INHIBITORS 1.803
The traditional Chinese medicine plant Schisandra Chinensis as source of new HIV-1 reverse transcriptase inhibitor scaffolds effective also on non-nucleoside resistant reverse transcriptases 1.798
Inhibition of HIV-1 Ribonuclease H activity by novel frangula-emodine derivatives 1.765
HIV-1 inhibiting activity of the essential oil of Ridolfia segetum and Oenanthe crocata 1.756
New anthraquinone derivatives as inhibitors of the HIV-1 reverse transcriptase-associated ribonuclease H function 1.725
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and Ribonuclease H activities effective also on non-nucleoside resistant RTs 1.720
Exploring new scaffolds for the inhibition of the Ribonuclease H function of RT HIV-1 1.711
dsRNA binding characterization of full length recombinant wild type and mutants Zaire ebolavirus VP35 1.710
Synthesis and biological evaluation of new dual inhibitors of HIV-1 associated functions 1.614
Effects of new quinizarin derivatives on both HCV NS5B RNA polymerase and HIV-1 reverse transcriptase associated ribonuclease H activities 1.610
Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen 1.586
From classic to innovative approaches in HIV-1 infection treatment 1.566
Development of a Raltegravir-based Photoaffinity-Labeled Probe for Human Immunodeficiency Virus-1 Integrase Capture 1.558
Anti-HIV-1 activity of compounds isolated from Hypericum hircinum. 1.548
Identification of highly conserved residues involved in inhibition of HIV-1 RNase H function by Diketo acid derivatives 1.541
Probing the importance of the g-quadruplex grooves for the activity of the anti-hiv-integrase aptamer t30923 1.481
A Homogeneous Time Resolved Fluorescence (HTRF) method for the evaluation of HIV-1 integrase dimerization, enzyme reactions and interaction with LEDGF/p75 1.468
Can the ever-promising target HIV reverse transcriptase-associated RNase H become a success story for drug development? 1.439
Shape based computer aided similarity screening: a valid tool in the discovery of new scaffolds for the inhibition of HIV-1 reverse transcriptase associated ribonuclease H function 1.435
Effect of Non-nucleoside Reverse Transcriptase Inhibitors on the HIV-1 Reverse Transcriptase Associated Ribonuclease-H Activity 1.393
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase (RT) -associated DNA polymerase and Ribonuclease H (RNase H) activities effective also on the RNase H activity of non-nucleoside resistant RTs 1.388
Natural Compounds Inhibit SARS-CoV-2 nsp13 Unwinding and ATPase Enzyme Activities 1.308
Cytopathic SARS-CoV-2 screening on VERO-E6 cells in a large-scale repurposing effort 1.224
null 1.214
Exploring new scaffolds for the dual inhibition of HIV-1 RT polymerase and ribonuclease associated functions 1.208
A combined shape-, 2D-fingerprint-and pharmacophore-based virtual screening for the identification of dual inhibitors targeting HIV-1 reverse transcriptase. 1.187
HIV-1 reverse transcriptase and K562 cell replication inhibition by Ridolfia segetum (L.) Moris essential oil 1.161
A combined cell based and site directed mutagenesis approach defines highly conserved residues involved in the selective inhibition of the HIV-1 ribonuclease H function by diketoacid derivatives 1.144
In Vitro Anti-HIV-1 Reverse Transcriptase and Integrase Properties of Punica granatum L. Leaves, Bark, and Peel Extracts and Their Main Compounds 1.125
Strigolactones as broad-spectrum antivirals against β-coronaviruses through targeting the main protease Mpro 1.094
Purification and functional characterization of the full length recombinant Ebola virus VP35 protein expressed in E. coli 1.066
Past and future. Current drugs targeting HIV-1 integrase and reverse transcriptase-associated ribonuclease H activity: single and dual active site inhibitors 1.055
Quinolinonyl Non-Diketo Acid Derivatives as Inhibitors of HIV-1 Ribonuclease H and Polymerase Functions of Reverse Transcriptase 992
Chemical Characterization and Anti-HIV-1 Activity Assessment of Iridoids and Flavonols from Scrophularia trifoliata 983
Totale 239.095
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Categoria #
all - tutte 315.966
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 315.966
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.458 0 0 0 0 0 0 0 0 0 0 0 1.458
2021/202213.416 1.338 1.020 642 772 1.064 1.094 720 579 1.260 1.273 1.812 1.842
2022/202321.107 1.698 2.901 2.540 2.044 1.399 2.491 1.086 1.683 1.162 1.243 1.870 990
2023/202420.613 905 749 1.251 1.736 2.153 3.614 2.934 1.418 986 1.195 1.758 1.914
2024/202544.636 10.914 13.148 6.932 4.236 1.988 2.388 3.362 145 411 305 323 484
2025/202610.809 704 353 1.285 918 938 730 1.638 983 736 1.356 750 418
Totale 262.191