UNICA IRIS Institutional Research Information System

ESPOSITO, FRANCESCA
 Distribuzione geografica
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Continente #
EU - Europa 200.113
NA - Nord America 6.629
AS - Asia 1.024
AF - Africa 17
Continente sconosciuto - Info sul continente non disponibili 10
OC - Oceania 5
SA - Sud America 5
Totale 207.803
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Nazione #
IT - Italia 198.377
US - Stati Uniti d'America 6.580
CN - Cina 671
UA - Ucraina 581
SE - Svezia 543
DE - Germania 226
FI - Finlandia 149
SG - Singapore 131
GB - Regno Unito 118
VN - Vietnam 71
CA - Canada 44
FR - Francia 44
IN - India 41
KR - Corea 24
HK - Hong Kong 18
TR - Turchia 15
IR - Iran 12
BE - Belgio 11
PK - Pakistan 11
PL - Polonia 11
EU - Europa 8
ES - Italia 7
JP - Giappone 7
NL - Olanda 7
CZ - Repubblica Ceca 6
IQ - Iraq 6
ID - Indonesia 5
RU - Federazione Russa 5
ZA - Sudafrica 5
AU - Australia 4
CH - Svizzera 4
LV - Lettonia 4
NO - Norvegia 4
TW - Taiwan 4
CL - Cile 3
DZ - Algeria 3
EG - Egitto 3
GR - Grecia 3
IE - Irlanda 3
MX - Messico 3
TN - Tunisia 3
A1 - Anonimo 2
AT - Austria 2
HR - Croazia 2
IL - Israele 2
MU - Mauritius 2
PT - Portogallo 2
SA - Arabia Saudita 2
TH - Thailandia 2
AE - Emirati Arabi Uniti 1
BR - Brasile 1
CO - Colombia 1
CR - Costa Rica 1
DO - Repubblica Dominicana 1
HU - Ungheria 1
LU - Lussemburgo 1
MA - Marocco 1
NZ - Nuova Zelanda 1
RO - Romania 1
SI - Slovenia 1
TJ - Tagikistan 1
Totale 207.803
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Città #
Cagliari 197.824
Fairfield 825
Woodbridge 764
Chandler 541
Ashburn 450
Nyköping 418
Houston 416
Seattle 360
Wilmington 359
Ann Arbor 352
Cambridge 304
Jacksonville 286
New York 217
Dearborn 198
Boardman 124
Shanghai 119
Nanjing 117
Boston 91
Beijing 88
Dong Ket 69
Redwood City 64
Helsinki 62
Singapore 53
San Diego 48
Herndon 40
Nanchang 33
Mountain View 31
Rome 30
Guangzhou 28
Shenyang 28
Milan 27
Changsha 24
Hebei 24
Los Angeles 23
Toronto 22
Seoul 21
Jiaxing 19
Orange 19
Atlanta 17
Ottawa 17
Norwalk 16
Sassari 16
Tianjin 16
Washington 15
Hong Kong 14
Jinan 14
Verona 14
Wuhan 14
London 13
Pune 13
Hangzhou 12
Brussels 11
Istanbul 11
Kunming 11
Phoenix 11
Falls Church 9
Napoli 9
Auburn Hills 8
Paris 8
Warsaw 8
Zhengzhou 8
Hefei 7
Redmond 7
Gujranwala 6
Jinhua 6
Menlo Park 6
Millbury 6
Mumbai 6
Ningbo 6
Siracusa 6
Chicago 5
Frankfurt am Main 5
Indiana 5
Kilburn 5
Quartu Sant'Elena 5
Antea 4
Bari 4
Carbonia 4
Chiswick 4
Cosenza 4
Hyderabad 4
Jakarta 4
Munich 4
Nanning 4
Oslo 4
Padova 4
Quartu Sant'elena 4
Rockville 4
Serramanna 4
Tappahannock 4
Trieste 4
Villanovafranca 4
Wuxi 4
Acton 3
Bad Bellingen 3
Brno 3
Bultei 3
Chengdu 3
Edinburgh 3
Greensboro 3
Totale 204.977
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Nome #
(3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro- 1H -indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase 5.091
Design, synthesis, and biological evaluation of 1,3-diarylpropenones as dual inhibitors of HIV-1 reverse transcriptase 4.125
Ribonuclease H/DNA polymerase HIV-1 reverse transcriptase dual inhibitor: mechanistic studies on the allosteric mode of action of isatin-based compound RMNC6 3.997
Biological activities of aerial parts extracts of Euphorbia characias 3.962
Euphorbia characias latex: Micromorphology of rubber particles and rubber transferase activity 3.405
Identification of Myricetin as Ebolavirus VP35-dsRNA interaction inhibitor through a novel fluorescence-based assay 3.287
Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 Reverse transcriptase-associated RNase H and RDDP functions 3.195
Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach 3.161
Sennoside A, derived from the traditional chinese medicine plant Rheum L., is a new dual HIV-1 inhibitor effective on HIV-1 replication 3.091
Dual HIV-1 reverse transcriptase and integrase inhibitors from Limonium morisianum Arrigoni, an endemic species of Sardinia (Italy) 3.048
Design and synthesis of new isatin derivatives as HIV-1 reverse transcriptase associated ribonuclease H inhibitors 2.988
Studies on Cycloheptathiophene-3-carboxamide Derivatives as Allosteric HIV-1 Ribonuclease H Inhibitors 2.967
Multi-target activity of Hemidesmus indicus decoction against innovative HIV-1 drug targets and characterization of Lupeol mode of action 2.966
New insights into the operative network of FaEO, an enone oxidoreductase from Fragaria x ananassa Duch 2.789
Prenylated phloroglucinols from Hypericum scruglii, an endemic species of Sardinia (Italy), as new dual HIV-1 inhibitors effective on HIV-1 replication 2.743
null 2.719
Inhibition of HIV-1 reverse transcriptase dimerization by small molecules 2.706
Purification and characterization of DR_2577 (SlpA) a major S-layer protein from Deinococcus radiodurans 2.699
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) shed light on the mechanism of action of a new Ribonuclease H/ DNA polymerase RT dual inhibitor 2.689
Onopordum illyricum L., a Mediterranean plant, as a source of anti HIV-1 compounds 2.672
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) enlighten the mechanism of action of a new Ribonuclease H/DNA polymerase RT dual inhibitor 2.659
Preliminary study of endemic plants of Sardinia as a source of new antiviral agents 2.650
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Single Site Dual Inhibitors of HIV-1 RT 2.645
Chelation motifs affecting metal-dependent viral enzymes: N′-acylhydrazone ligands as dual target inhibitors of HIV-1 Integrase and Reverse Transcriptase Ribonuclease H domain 2.617
From the traditional Chinese medicine plant Schisandra chinensis new scaffolds effective on HIV-1 reverse transcriptase resistant to non-nucleoside inhibitors 2.595
Hypericum hircinum L. components as new single-molecule inhibitors of both HIV-1 reverse transcriptase-associated DNA polymerase and ribonuclease H activities 2.576
S-layer proteins as a source of carotenoids: Isolation of the carotenoid cofactor deinoxanthin from its S-layer protein DR_2577 2.563
RhVI1 is a membrane-anchored vacuolar invertase highly expressed in Rosa hybrida L. petals 2.497
Natural Product Kuwanon-L Inhibits HIV-1 Replication through Multiple Target Binding 2.490
On the S-layer of Thermus thermophilus and the assembling of its main protein SIpA 2.477
Chromenone derivatives as a versatile scaffold with dual mode of inhibition of HIV-1 reverse transcriptase-associated Ribonuclease H function and integrase activity 2.448
New insights into the interaction between pyrrolyl diketoacids and HIV-1 integrase active site and comparison with RNase H 2.436
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Dual Inhibitors of HIV-1 RT. 2.360
Structure-guided approach identifies a novel class of HIV-1 Ribonuclease H inhibitors: Binding mode insights through magnesium complexation and site-directed mutagenesis studies 2.317
Identification of a novel HERV-K(HML10): comprehensive characterization and comparative analysis in non-human primates provide insights about HML10 proviruses structure and diffusion 2.277
Chalcones as novel dual inhibitors of HIV-1 reverse transcriptase 2.234
An efficient route to novel uracil-based drug-like molecules 2.185
3-[2-(4-aryl-1,3-thiazol-2-yl)hydrazin-1-ylidene]-1H-indol-2-ones as new potential dual inhibitors of polimerase and ribonuclease HIV-1 RT associated function 2.157
Structure-Activity Relationship of Pyrrolyl Diketo Acid Derivatives as Dual Inhibitors of HIV-1 Integrase and Reverse Transcriptase Ribonuclease H Domain 2.147
Validation of a computed radiography device to monitor the HIV-1 RNase H activity 2.134
A Luciferase Reporter Gene Assay to Measure Ebola Virus Viral Protein 35–Associated Inhibition of Double-Stranded RNA–Stimulated, Retinoic Acid–Inducible Gene 1–Mediated Induction of Interferon β 2.093
Exploring new scaffolds for the inibition of the Ribonuclease H function of RT HIV-1 2.053
Improvement of the activity of the anti-HIV-1 integrase aptamer T30175 by introducing a modified thymidine into the loops 2.051
Investigation on the sucrose binding pocket of HIV-1 Integrase by molecular dynamics and synergy experiments 2.027
Development and identification of a novel anti-HIV-1 peptide derived by modification of the N-terminal domain of HIV-1 integrase 1.987
Design and synthesis of new Isatin derivatives as HIV-1 Reverse Transcriptase associated Ribonuclease H inhibitors twenty-fourth 1.951
Inhibitory effect of 2,3,5,6-tetrafluoro-4-[4-(Aryl)-1H-1,2,3-triazol-1-yl]benzenesulfonamide derivatives on HIV reverse transcriptase associated rnase H activities 1.945
Inhibition of HIV-1 reverse transcriptase associated activities by the hydroalcoholic extract of Casimiroa edulis seeds 1.917
Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach 1.862
2-(Arylamino)-6-(trifluoromethyl)nicotinic Acid Derivatives: New HIV-1 RT Dual Inhibitors Active on Viral Replication 1.862
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases 1.859
null 1.851
Kuwanon-L as a new allosteric HIV-1 integrase inhibitor: molecular modeling and biological evaluation 1.845
Mutagenic study on HIV-1 reverse transcriptase to explore the mechanism of action of HIV-1 reverse transcriptase dual inhibitors 1.827
null 1.820
Discovery of dihydroxyindole-2-carboxylic acid derivatives as dual allosteric HIV-1 Integrase and Reverse Transcriptase associated Ribonuclease H inhibitors 1.816
6-(1-Benzyl-1H-pyrrol-2-yl)-2,4-dioxo-5-hexenoic acids as dual inhibitors of recombinant HIV-1 integrase and ribonuclease H, synthesized by a parallel synthesis approach 1.799
Targeting HIV-1 RNase H: N'-(2-Hydroxy-benzylidene)-3,4,5-Trihydroxybenzoylhydrazone as Selective Inhibitor Active against NNRTIs-Resistant Variants 1.781
Isatin derivatives as new scaffolds for HIV-1 reverse transcriptase associated RNase H and RDDP dual inhibitors 1.760
Design of new inhibitors of the HIV-1 Reverse Transcriptase associated Ribonuclease H function: a synthetic approach 1.713
Design, synthesis and biolgical activity evaluation of new HIV-1 reverse transcriptase dual inhibitors 1.660
Pyrrolyl Pyrazoles as Non-Diketo Acid Inhibitors of the HIV-1 Ribonuclease H Function of Reverse Transcriptase 1.593
HIV-1 inhibiting activity of the essential oil of Ridolfia segetum and Oenanthe crocata 1.551
Inhibition of HIV-1 Ribonuclease H activity by novel frangula-emodine derivatives 1.548
Identification of new scaffolds for the inhibition of HIV-1 Reverse Transcriptase associated Ribonuclease H function by means of shape based similarity screening 1.540
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and Ribonuclease H activities effective also on non-nucleoside resistant RTs 1.505
SITE DIRECT MUTAGENESIS AND KINETIC STUDIES TO EXPLORE THE MECHANISM OF ACTION OF ISATIN DERIVATIVES AS HIV-1 REVERSE TRANSCRIPTASE DUAL INHIBITORS 1.498
New anthraquinone derivatives as inhibitors of the HIV-1 reverse transcriptase-associated ribonuclease H function 1.493
dsRNA binding characterization of full length recombinant wild type and mutants Zaire ebolavirus VP35 1.480
The traditional Chinese medicine plant Schisandra Chinensis as source of new HIV-1 reverse transcriptase inhibitor scaffolds effective also on non-nucleoside resistant reverse transcriptases 1.474
Exploring new scaffolds for the inhibition of the Ribonuclease H function of RT HIV-1 1.441
Scaffold hopping and optimisation of 3’,4’-dihydroxyphenyl- containing thienopyrimidinones: synthesis of quinazolinone derivatives as novel allosteric inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H 1.429
Design, synthesis and biological activity evaluation of new HIV-1 reverse transcriptase dual inhibitors 1.423
Effects of new quinizarin derivatives on both HCV NS5B RNA polymerase and HIV-1 reverse transcriptase associated ribonuclease H activities 1.412
From classic to innovative approaches in HIV-1 infection treatment 1.332
Synthesis and biological evaluation of new dual inhibitors of HIV-1 associated functions 1.323
Identification of highly conserved residues involved in inhibition of HIV-1 RNase H function by Diketo acid derivatives 1.321
Anti-HIV-1 activity of compounds isolated from Hypericum hircinum. 1.318
Development of a Raltegravir-based Photoaffinity-Labeled Probe for Human Immunodeficiency Virus-1 Integrase Capture 1.286
Can the ever-promising target HIV reverse transcriptase-associated RNase H become a success story for drug development? 1.277
A Homogeneous Time Resolved Fluorescence (HTRF) method for the evaluation of HIV-1 integrase dimerization, enzyme reactions and interaction with LEDGF/p75 1.270
Effect of Non-nucleoside Reverse Transcriptase Inhibitors on the HIV-1 Reverse Transcriptase Associated Ribonuclease-H Activity 1.251
null 1.214
Shape based computer aided similarity screening: a valid tool in the discovery of new scaffolds for the inhibition of HIV-1 reverse transcriptase associated ribonuclease H function 1.178
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase (RT) -associated DNA polymerase and Ribonuclease H (RNase H) activities effective also on the RNase H activity of non-nucleoside resistant RTs 1.176
Probing the importance of the g-quadruplex grooves for the activity of the anti-hiv-integrase aptamer t30923 1.151
Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen 1.116
HIV-1 reverse transcriptase and K562 cell replication inhibition by Ridolfia segetum (L.) Moris essential oil 1.009
A combined shape-, 2D-fingerprint-and pharmacophore-based virtual screening for the identification of dual inhibitors targeting HIV-1 reverse transcriptase. 926
Past and future. Current drugs targeting HIV-1 integrase and reverse transcriptase-associated ribonuclease H activity: single and dual active site inhibitors 837
Development of 3-hydroxyquinolein-2(1H)-ones as inhibitors of HIV-1 integrase and ribonuclease H function of reverse transcriptase 834
A combined cell based and site directed mutagenesis approach defines highly conserved residues involved in the selective inhibition of the HIV-1 ribonuclease H function by diketoacid derivatives 796
Exploring new scaffolds for the dual inhibition of HIV-1 RT polymerase and ribonuclease associated functions 794
In Vitro Anti-HIV-1 Reverse Transcriptase and Integrase Properties of Punica granatum L. Leaves, Bark, and Peel Extracts and Their Main Compounds 715
Development of a series of 3-hydroxyquinolin-2(1H)-ones as selective inhibitors of HIV-1 reverse transcriptase associated RNase H activity 713
Hemidesmus Indicus: Dall’antica Tradizone Ayurvedica Alle Potenzilità Anti-HIV1 E Nei Disordini Multifattoriali 667
HIV-1 Reverse Transcriptase still remains a new drug target: Structure, Function, Classical inhibitors and new inhibitors with innovative mechanism of action 661
Natural Compounds Inhibit SARS-CoV-2 nsp13 Unwinding and ATPase Enzyme Activities 650
Quinolinonyl Non-Diketo Acid Derivatives as Inhibitors of HIV-1 Ribonuclease H and Polymerase Functions of Reverse Transcriptase 633
Structural and biochemical analysis of the dual inhibition of mg-132 against sars-cov-2 main protease (Mpro/3clpro) and human cathepsin-l 632
Totale 197.710
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Categoria #
all - tutte 238.842
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 238.842
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202037.050 1.882 1.587 302 587 12.748 9.736 5.182 977 652 1.028 791 1.578
2020/202154.305 1.646 1.809 2.383 14.910 10.176 5.582 4.220 3.507 1.363 3.344 3.907 1.458
2021/202213.416 1.338 1.020 642 772 1.064 1.094 720 579 1.260 1.273 1.812 1.842
2022/202321.107 1.698 2.901 2.540 2.044 1.399 2.491 1.086 1.683 1.162 1.243 1.870 990
2023/202420.613 905 749 1.251 1.736 2.153 3.614 2.934 1.418 986 1.195 1.758 1.914
2024/20251.525 1.525 0 0 0 0 0 0 0 0 0 0 0
Totale 208.271