UNICA IRIS Institutional Research Information System

ESPOSITO, FRANCESCA
 Distribuzione geografica
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Continente #
EU - Europa 185.821
NA - Nord America 6.338
AS - Asia 645
AF - Africa 17
Continente sconosciuto - Info sul continente non disponibili 10
OC - Oceania 5
SA - Sud America 4
Totale 192.840
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Nazione #
IT - Italia 184.093
US - Stati Uniti d'America 6.289
UA - Ucraina 581
SE - Svezia 543
CN - Cina 470
DE - Germania 206
FI - Finlandia 149
GB - Regno Unito 124
VN - Vietnam 71
CA - Canada 44
FR - Francia 42
IN - India 41
BE - Belgio 29
PK - Pakistan 11
PL - Polonia 11
IR - Iran 10
EU - Europa 8
ES - Italia 7
JP - Giappone 7
NL - Olanda 7
IQ - Iraq 6
RU - Federazione Russa 5
TR - Turchia 5
ZA - Sudafrica 5
AU - Australia 4
ID - Indonesia 4
LV - Lettonia 4
NO - Norvegia 4
CL - Cile 3
CZ - Repubblica Ceca 3
DZ - Algeria 3
EG - Egitto 3
HK - Hong Kong 3
KR - Corea 3
MX - Messico 3
SG - Singapore 3
TN - Tunisia 3
TW - Taiwan 3
A1 - Anonimo 2
CH - Svizzera 2
HR - Croazia 2
IE - Irlanda 2
IL - Israele 2
MU - Mauritius 2
PT - Portogallo 2
SA - Arabia Saudita 2
TH - Thailandia 2
AE - Emirati Arabi Uniti 1
BR - Brasile 1
CR - Costa Rica 1
DO - Repubblica Dominicana 1
GR - Grecia 1
HU - Ungheria 1
LU - Lussemburgo 1
MA - Marocco 1
NZ - Nuova Zelanda 1
RO - Romania 1
SI - Slovenia 1
TJ - Tagikistan 1
Totale 192.840
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Città #
Cagliari 183.572
Fairfield 825
Woodbridge 764
Chandler 541
Nyköping 418
Houston 416
Ashburn 412
Wilmington 359
Ann Arbor 352
Seattle 345
Cambridge 304
Jacksonville 286
Dearborn 198
Boardman 124
Nanjing 117
Boston 91
Beijing 80
Dong Ket 69
Redwood City 64
Helsinki 62
San Diego 48
Herndon 40
Nanchang 33
Mountain View 31
Brussels 29
Shenyang 28
Milan 27
Changsha 24
Hebei 24
Guangzhou 23
Rome 23
Toronto 22
London 20
Orange 19
Atlanta 17
Jiaxing 17
Ottawa 17
Norwalk 16
Tianjin 16
Washington 15
Verona 14
Jinan 13
Pune 13
Sassari 13
Kunming 11
Phoenix 11
Shanghai 11
Falls Church 9
Hangzhou 9
Napoli 9
Auburn Hills 8
Los Angeles 8
Paris 8
Warsaw 8
Zhengzhou 8
Hefei 7
Redmond 7
Gujranwala 6
Menlo Park 6
Millbury 6
Mumbai 6
Ningbo 6
Siracusa 6
Acton 5
Chicago 5
Indiana 5
New York 5
Quartu Sant'Elena 5
Antea 4
Bari 4
Carbonia 4
Chiswick 4
Cosenza 4
Hyderabad 4
Jakarta 4
Nanning 4
Oslo 4
Padova 4
Quartu Sant'elena 4
Rockville 4
Serramanna 4
Tappahannock 4
Villanovafranca 4
Wuhan 4
Bultei 3
Chengdu 3
Edinburgh 3
Greensboro 3
Hanover 3
Islamabad 3
Islington 3
New Bedfont 3
Nürnberg 3
Olbia 3
Selargius 3
Shenzhen 3
Taizhou 3
Thohoyandou 3
Tokyo 3
Torino 3
Totale 190.228
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Nome #
(3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro- 1H -indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase 4.025
Design, synthesis, and biological evaluation of 1,3-diarylpropenones as dual inhibitors of HIV-1 reverse transcriptase 3.964
Ribonuclease H/DNA polymerase HIV-1 reverse transcriptase dual inhibitor: mechanistic studies on the allosteric mode of action of isatin-based compound RMNC6 3.855
Biological activities of aerial parts extracts of Euphorbia characias 3.806
Euphorbia characias latex: Micromorphology of rubber particles and rubber transferase activity 3.275
Identification of Myricetin as Ebolavirus VP35-dsRNA interaction inhibitor through a novel fluorescence-based assay 3.053
Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach 3.008
Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 Reverse transcriptase-associated RNase H and RDDP functions 2.997
Sennoside A, derived from the traditional chinese medicine plant Rheum L., is a new dual HIV-1 inhibitor effective on HIV-1 replication 2.951
Dual HIV-1 reverse transcriptase and integrase inhibitors from Limonium morisianum Arrigoni, an endemic species of Sardinia (Italy) 2.861
Design and synthesis of new isatin derivatives as HIV-1 reverse transcriptase associated ribonuclease H inhibitors 2.852
Multi-target activity of Hemidesmus indicus decoction against innovative HIV-1 drug targets and characterization of Lupeol mode of action 2.832
Studies on Cycloheptathiophene-3-carboxamide Derivatives as Allosteric HIV-1 Ribonuclease H Inhibitors 2.800
null 2.719
New insights into the operative network of FaEO, an enone oxidoreductase from Fragaria x ananassa Duch 2.662
Prenylated phloroglucinols from Hypericum scruglii, an endemic species of Sardinia (Italy), as new dual HIV-1 inhibitors effective on HIV-1 replication 2.606
Purification and characterization of DR_2577 (SlpA) a major S-layer protein from Deinococcus radiodurans 2.596
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) shed light on the mechanism of action of a new Ribonuclease H/ DNA polymerase RT dual inhibitor 2.590
Inhibition of HIV-1 reverse transcriptase dimerization by small molecules 2.550
Preliminary study of endemic plants of Sardinia as a source of new antiviral agents 2.549
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) enlighten the mechanism of action of a new Ribonuclease H/DNA polymerase RT dual inhibitor 2.540
Onopordum illyricum L., a Mediterranean plant, as a source of anti HIV-1 compounds 2.539
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Single Site Dual Inhibitors of HIV-1 RT 2.537
Chelation motifs affecting metal-dependent viral enzymes: N′-acylhydrazone ligands as dual target inhibitors of HIV-1 Integrase and Reverse Transcriptase Ribonuclease H domain 2.459
From the traditional Chinese medicine plant Schisandra chinensis new scaffolds effective on HIV-1 reverse transcriptase resistant to non-nucleoside inhibitors 2.456
Hypericum hircinum L. components as new single-molecule inhibitors of both HIV-1 reverse transcriptase-associated DNA polymerase and ribonuclease H activities 2.456
S-layer proteins as a source of carotenoids: Isolation of the carotenoid cofactor deinoxanthin from its S-layer protein DR_2577 2.454
RhVI1 is a membrane-anchored vacuolar invertase highly expressed in Rosa hybrida L. petals 2.379
On the S-layer of Thermus thermophilus and the assembling of its main protein SIpA 2.336
Natural Product Kuwanon-L Inhibits HIV-1 Replication through Multiple Target Binding 2.329
Chromenone derivatives as a versatile scaffold with dual mode of inhibition of HIV-1 reverse transcriptase-associated Ribonuclease H function and integrase activity 2.320
New insights into the interaction between pyrrolyl diketoacids and HIV-1 integrase active site and comparison with RNase H 2.287
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Dual Inhibitors of HIV-1 RT. 2.237
Structure-guided approach identifies a novel class of HIV-1 Ribonuclease H inhibitors: Binding mode insights through magnesium complexation and site-directed mutagenesis studies 2.161
An efficient route to novel uracil-based drug-like molecules 2.123
Identification of a novel HERV-K(HML10): comprehensive characterization and comparative analysis in non-human primates provide insights about HML10 proviruses structure and diffusion 2.123
Chalcones as novel dual inhibitors of HIV-1 reverse transcriptase 2.111
Structure-Activity Relationship of Pyrrolyl Diketo Acid Derivatives as Dual Inhibitors of HIV-1 Integrase and Reverse Transcriptase Ribonuclease H Domain 2.067
Validation of a computed radiography device to monitor the HIV-1 RNase H activity 2.042
3-[2-(4-aryl-1,3-thiazol-2-yl)hydrazin-1-ylidene]-1H-indol-2-ones as new potential dual inhibitors of polimerase and ribonuclease HIV-1 RT associated function 2.025
A Luciferase Reporter Gene Assay to Measure Ebola Virus Viral Protein 35–Associated Inhibition of Double-Stranded RNA–Stimulated, Retinoic Acid–Inducible Gene 1–Mediated Induction of Interferon β 1.992
Investigation on the sucrose binding pocket of HIV-1 Integrase by molecular dynamics and synergy experiments 1.968
Exploring new scaffolds for the inibition of the Ribonuclease H function of RT HIV-1 1.942
Improvement of the activity of the anti-HIV-1 integrase aptamer T30175 by introducing a modified thymidine into the loops 1.893
Development and identification of a novel anti-HIV-1 peptide derived by modification of the N-terminal domain of HIV-1 integrase 1.874
null 1.851
Inhibition of HIV-1 reverse transcriptase associated activities by the hydroalcoholic extract of Casimiroa edulis seeds 1.832
Design and synthesis of new Isatin derivatives as HIV-1 Reverse Transcriptase associated Ribonuclease H inhibitors twenty-fourth 1.829
null 1.820
Inhibitory effect of 2,3,5,6-tetrafluoro-4-[4-(Aryl)-1H-1,2,3-triazol-1-yl]benzenesulfonamide derivatives on HIV reverse transcriptase associated rnase H activities 1.801
Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach 1.779
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases 1.754
Kuwanon-L as a new allosteric HIV-1 integrase inhibitor: molecular modeling and biological evaluation 1.744
2-(Arylamino)-6-(trifluoromethyl)nicotinic Acid Derivatives: New HIV-1 RT Dual Inhibitors Active on Viral Replication 1.724
Mutagenic study on HIV-1 reverse transcriptase to explore the mechanism of action of HIV-1 reverse transcriptase dual inhibitors 1.697
6-(1-Benzyl-1H-pyrrol-2-yl)-2,4-dioxo-5-hexenoic acids as dual inhibitors of recombinant HIV-1 integrase and ribonuclease H, synthesized by a parallel synthesis approach 1.685
Isatin derivatives as new scaffolds for HIV-1 reverse transcriptase associated RNase H and RDDP dual inhibitors 1.662
Discovery of dihydroxyindole-2-carboxylic acid derivatives as dual allosteric HIV-1 Integrase and Reverse Transcriptase associated Ribonuclease H inhibitors 1.661
Targeting HIV-1 RNase H: N'-(2-Hydroxy-benzylidene)-3,4,5-Trihydroxybenzoylhydrazone as Selective Inhibitor Active against NNRTIs-Resistant Variants 1.638
Design of new inhibitors of the HIV-1 Reverse Transcriptase associated Ribonuclease H function: a synthetic approach 1.622
Design, synthesis and biolgical activity evaluation of new HIV-1 reverse transcriptase dual inhibitors 1.549
HIV-1 inhibiting activity of the essential oil of Ridolfia segetum and Oenanthe crocata 1.478
Inhibition of HIV-1 Ribonuclease H activity by novel frangula-emodine derivatives 1.475
Pyrrolyl Pyrazoles as Non-Diketo Acid Inhibitors of the HIV-1 Ribonuclease H Function of Reverse Transcriptase 1.472
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and Ribonuclease H activities effective also on non-nucleoside resistant RTs 1.437
Identification of new scaffolds for the inhibition of HIV-1 Reverse Transcriptase associated Ribonuclease H function by means of shape based similarity screening 1.437
dsRNA binding characterization of full length recombinant wild type and mutants Zaire ebolavirus VP35 1.410
New anthraquinone derivatives as inhibitors of the HIV-1 reverse transcriptase-associated ribonuclease H function 1.405
SITE DIRECT MUTAGENESIS AND KINETIC STUDIES TO EXPLORE THE MECHANISM OF ACTION OF ISATIN DERIVATIVES AS HIV-1 REVERSE TRANSCRIPTASE DUAL INHIBITORS 1.386
The traditional Chinese medicine plant Schisandra Chinensis as source of new HIV-1 reverse transcriptase inhibitor scaffolds effective also on non-nucleoside resistant reverse transcriptases 1.367
Effects of new quinizarin derivatives on both HCV NS5B RNA polymerase and HIV-1 reverse transcriptase associated ribonuclease H activities 1.346
Exploring new scaffolds for the inhibition of the Ribonuclease H function of RT HIV-1 1.339
Design, synthesis and biological activity evaluation of new HIV-1 reverse transcriptase dual inhibitors 1.288
Scaffold hopping and optimisation of 3’,4’-dihydroxyphenyl- containing thienopyrimidinones: synthesis of quinazolinone derivatives as novel allosteric inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H 1.256
Identification of highly conserved residues involved in inhibition of HIV-1 RNase H function by Diketo acid derivatives 1.247
Synthesis and biological evaluation of new dual inhibitors of HIV-1 associated functions 1.245
From classic to innovative approaches in HIV-1 infection treatment 1.234
Anti-HIV-1 activity of compounds isolated from Hypericum hircinum. 1.214
null 1.214
Can the ever-promising target HIV reverse transcriptase-associated RNase H become a success story for drug development? 1.207
Effect of Non-nucleoside Reverse Transcriptase Inhibitors on the HIV-1 Reverse Transcriptase Associated Ribonuclease-H Activity 1.199
A Homogeneous Time Resolved Fluorescence (HTRF) method for the evaluation of HIV-1 integrase dimerization, enzyme reactions and interaction with LEDGF/p75 1.198
Development of a Raltegravir-based Photoaffinity-Labeled Probe for Human Immunodeficiency Virus-1 Integrase Capture 1.132
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase (RT) -associated DNA polymerase and Ribonuclease H (RNase H) activities effective also on the RNase H activity of non-nucleoside resistant RTs 1.100
Shape based computer aided similarity screening: a valid tool in the discovery of new scaffolds for the inhibition of HIV-1 reverse transcriptase associated ribonuclease H function 1.052
Probing the importance of the g-quadruplex grooves for the activity of the anti-hiv-integrase aptamer t30923 975
HIV-1 reverse transcriptase and K562 cell replication inhibition by Ridolfia segetum (L.) Moris essential oil 967
Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen 958
A combined shape-, 2D-fingerprint-and pharmacophore-based virtual screening for the identification of dual inhibitors targeting HIV-1 reverse transcriptase. 844
Development of 3-hydroxyquinolein-2(1H)-ones as inhibitors of HIV-1 integrase and ribonuclease H function of reverse transcriptase 783
Past and future. Current drugs targeting HIV-1 integrase and reverse transcriptase-associated ribonuclease H activity: single and dual active site inhibitors 776
A combined cell based and site directed mutagenesis approach defines highly conserved residues involved in the selective inhibition of the HIV-1 ribonuclease H function by diketoacid derivatives 724
Development of a series of 3-hydroxyquinolin-2(1H)-ones as selective inhibitors of HIV-1 reverse transcriptase associated RNase H activity 648
Exploring new scaffolds for the dual inhibition of HIV-1 RT polymerase and ribonuclease associated functions 631
Hemidesmus Indicus: Dall’antica Tradizone Ayurvedica Alle Potenzilità Anti-HIV1 E Nei Disordini Multifattoriali 606
HIV-1 Reverse Transcriptase still remains a new drug target: Structure, Function, Classical inhibitors and new inhibitors with innovative mechanism of action 593
Development of a series of 3-hydroxyquinolein-2(1H)-ones as selective inhibitors of HIV-1 reverse transcriptase associated RNase H activity 588
In Vitro Anti-HIV-1 Reverse Transcriptase and Integrase Properties of Punica granatum L. Leaves, Bark, and Peel Extracts and Their Main Compounds 548
Natural Compounds Inhibit SARS-CoV-2 nsp13 Unwinding and ATPase Enzyme Activities 531
Quinolinonyl Non-Diketo Acid Derivatives as Inhibitors of HIV-1 Ribonuclease H and Polymerase Functions of Reverse Transcriptase 511
Totale 185.670
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Categoria #
all - tutte 214.684
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 214.684
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/20194.550 0 0 0 0 0 776 699 528 512 511 968 556
2019/202037.050 1.882 1.587 302 587 12.748 9.736 5.182 977 652 1.028 791 1.578
2020/202154.305 1.646 1.809 2.383 14.910 10.176 5.582 4.220 3.507 1.363 3.344 3.907 1.458
2021/202213.416 1.338 1.020 642 772 1.064 1.094 720 579 1.260 1.273 1.812 1.842
2022/202321.128 1.698 2.901 2.540 2.044 1.399 2.491 1.087 1.684 1.168 1.245 1.874 997
2023/20247.145 906 751 1.256 1.739 2.163 330 0 0 0 0 0 0
Totale 193.299