ESPOSITO, FRANCESCA
 Distribuzione geografica
Continente #
EU - Europa 244.821
NA - Nord America 9.745
AS - Asia 4.612
SA - Sud America 725
AF - Africa 168
Continente sconosciuto - Info sul continente non disponibili 10
OC - Oceania 7
Totale 260.088
Nazione #
IT - Italia 242.264
US - Stati Uniti d'America 9.608
SG - Singapore 1.778
CN - Cina 1.624
SE - Svezia 628
UA - Ucraina 597
BR - Brasile 545
VN - Vietnam 400
DE - Germania 329
FI - Finlandia 301
FR - Francia 225
GB - Regno Unito 197
IN - India 139
HK - Hong Kong 133
KR - Corea 92
CA - Canada 90
AR - Argentina 79
BD - Bangladesh 58
MA - Marocco 58
NL - Olanda 55
TR - Turchia 51
IQ - Iraq 50
JP - Giappone 50
ZA - Sudafrica 42
PK - Pakistan 40
PL - Polonia 38
AT - Austria 37
MX - Messico 33
EC - Ecuador 31
ES - Italia 28
ID - Indonesia 27
RU - Federazione Russa 23
SA - Arabia Saudita 23
BE - Belgio 21
UZ - Uzbekistan 21
VE - Venezuela 20
CO - Colombia 18
TN - Tunisia 17
IE - Irlanda 14
IR - Iran 14
KE - Kenya 13
PH - Filippine 13
EG - Egitto 11
TW - Taiwan 11
AZ - Azerbaigian 10
AE - Emirati Arabi Uniti 9
CZ - Repubblica Ceca 9
DZ - Algeria 9
JO - Giordania 9
EU - Europa 8
NP - Nepal 8
BO - Bolivia 7
GE - Georgia 7
UY - Uruguay 7
CL - Cile 6
IL - Israele 6
LV - Lettonia 6
MY - Malesia 6
NO - Norvegia 6
PE - Perù 6
AL - Albania 5
AU - Australia 5
CH - Svizzera 5
KG - Kirghizistan 5
LB - Libano 5
PT - Portogallo 5
ET - Etiopia 4
GR - Grecia 4
HU - Ungheria 4
KZ - Kazakistan 4
LT - Lituania 4
PY - Paraguay 4
RO - Romania 4
CR - Costa Rica 3
DK - Danimarca 3
DO - Repubblica Dominicana 3
LU - Lussemburgo 3
MU - Mauritius 3
NI - Nicaragua 3
TH - Thailandia 3
A1 - Anonimo 2
AM - Armenia 2
CI - Costa d'Avorio 2
HR - Croazia 2
KH - Cambogia 2
NZ - Nuova Zelanda 2
OM - Oman 2
PS - Palestinian Territory 2
SR - Suriname 2
SY - Repubblica araba siriana 2
TT - Trinidad e Tobago 2
AO - Angola 1
BG - Bulgaria 1
BJ - Benin 1
BN - Brunei Darussalam 1
BW - Botswana 1
CG - Congo 1
CY - Cipro 1
GA - Gabon 1
GP - Guadalupe 1
Totale 260.075
Città #
Cagliari 236.371
Uta 5.175
Singapore 943
Ashburn 933
Fairfield 825
Woodbridge 764
Chandler 541
Dallas 538
San Jose 440
Houston 419
Nyköping 418
Boardman 385
Seattle 367
Wilmington 361
Ann Arbor 352
Beijing 327
Cambridge 305
Jacksonville 287
New York 257
Dearborn 198
Helsinki 184
Los Angeles 184
Santa Clara 143
Council Bluffs 141
Shanghai 131
The Dalles 128
Lauterbourg 124
Nanjing 119
Hong Kong 118
Ho Chi Minh City 108
Boston 107
Hefei 104
Seoul 81
Hanoi 76
Dong Ket 69
Redwood City 64
Buffalo 63
Munich 55
Rome 54
San Diego 50
Milan 44
Redondo Beach 41
Guangzhou 40
Herndon 40
São Paulo 40
Tokyo 40
Casablanca 39
Nanchang 36
Changsha 32
Warsaw 32
Amsterdam 31
Atlanta 31
Chicago 31
Mountain View 31
Shenyang 31
Tianjin 31
London 28
Toronto 27
Orem 25
Rio de Janeiro 25
Frankfurt am Main 24
Hebei 24
Vienna 23
Baghdad 21
Jiaxing 21
Phoenix 21
Chennai 20
Montreal 20
Orange 20
Tashkent 19
Hangzhou 18
Istanbul 18
Johannesburg 18
Washington 18
Brooklyn 17
Ottawa 17
Shenzhen 17
Da Nang 16
Guayaquil 16
Mumbai 16
Norwalk 16
Sassari 16
Turku 16
Jinan 15
Lappeenranta 15
Nuremberg 15
Pune 15
Wuhan 15
San Francisco 14
Stockholm 14
Verona 14
Brussels 13
Kunming 13
Lahore 13
Zhengzhou 13
Contagem 11
Denver 11
Dhaka 11
Dublin 11
Jakarta 11
Totale 253.640
Nome #
(3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro- 1H -indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase 14.717
Design, synthesis, and biological evaluation of 1,3-diarylpropenones as dual inhibitors of HIV-1 reverse transcriptase 4.518
Biological activities of aerial parts extracts of Euphorbia characias 4.439
Ribonuclease H/DNA polymerase HIV-1 reverse transcriptase dual inhibitor: mechanistic studies on the allosteric mode of action of isatin-based compound RMNC6 4.322
Identification of Myricetin as Ebolavirus VP35-dsRNA interaction inhibitor through a novel fluorescence-based assay 3.744
Euphorbia characias latex: Micromorphology of rubber particles and rubber transferase activity 3.673
Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 Reverse transcriptase-associated RNase H and RDDP functions 3.513
Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach 3.477
Dual HIV-1 reverse transcriptase and integrase inhibitors from Limonium morisianum Arrigoni, an endemic species of Sardinia (Italy) 3.442
Sennoside A, derived from the traditional chinese medicine plant Rheum L., is a new dual HIV-1 inhibitor effective on HIV-1 replication 3.426
Design and synthesis of new isatin derivatives as HIV-1 reverse transcriptase associated ribonuclease H inhibitors 3.335
Studies on Cycloheptathiophene-3-carboxamide Derivatives as Allosteric HIV-1 Ribonuclease H Inhibitors 3.303
Multi-target activity of Hemidesmus indicus decoction against innovative HIV-1 drug targets and characterization of Lupeol mode of action 3.293
New insights into the operative network of FaEO, an enone oxidoreductase from Fragaria x ananassa Duch 3.107
S-layer proteins as a source of carotenoids: Isolation of the carotenoid cofactor deinoxanthin from its S-layer protein DR_2577 3.090
Inhibition of HIV-1 reverse transcriptase dimerization by small molecules 3.072
Prenylated phloroglucinols from Hypericum scruglii, an endemic species of Sardinia (Italy), as new dual HIV-1 inhibitors effective on HIV-1 replication 3.046
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Dual Inhibitors of HIV-1 RT. 3.031
Onopordum illyricum L., a Mediterranean plant, as a source of anti HIV-1 compounds 2.998
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) enlighten the mechanism of action of a new Ribonuclease H/DNA polymerase RT dual inhibitor 2.963
Purification and characterization of DR_2577 (SlpA) a major S-layer protein from Deinococcus radiodurans 2.958
Preliminary study of endemic plants of Sardinia as a source of new antiviral agents 2.927
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Single Site Dual Inhibitors of HIV-1 RT 2.913
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) shed light on the mechanism of action of a new Ribonuclease H/ DNA polymerase RT dual inhibitor 2.901
From the traditional Chinese medicine plant Schisandra chinensis new scaffolds effective on HIV-1 reverse transcriptase resistant to non-nucleoside inhibitors 2.889
Structure-guided approach identifies a novel class of HIV-1 Ribonuclease H inhibitors: Binding mode insights through magnesium complexation and site-directed mutagenesis studies 2.884
Chelation motifs affecting metal-dependent viral enzymes: N′-acylhydrazone ligands as dual target inhibitors of HIV-1 Integrase and Reverse Transcriptase Ribonuclease H domain 2.877
Hypericum hircinum L. components as new single-molecule inhibitors of both HIV-1 reverse transcriptase-associated DNA polymerase and ribonuclease H activities 2.870
On the S-layer of Thermus thermophilus and the assembling of its main protein SIpA 2.841
Natural Product Kuwanon-L Inhibits HIV-1 Replication through Multiple Target Binding 2.829
RhVI1 is a membrane-anchored vacuolar invertase highly expressed in Rosa hybrida L. petals 2.810
Mutagenic study on HIV-1 reverse transcriptase to explore the mechanism of action of HIV-1 reverse transcriptase dual inhibitors 2.767
Chromenone derivatives as a versatile scaffold with dual mode of inhibition of HIV-1 reverse transcriptase-associated Ribonuclease H function and integrase activity 2.728
null 2.719
New insights into the interaction between pyrrolyl diketoacids and HIV-1 integrase active site and comparison with RNase H 2.707
3-[2-(4-aryl-1,3-thiazol-2-yl)hydrazin-1-ylidene]-1H-indol-2-ones as new potential dual inhibitors of polimerase and ribonuclease HIV-1 RT associated function 2.606
Identification of a novel HERV-K(HML10): comprehensive characterization and comparative analysis in non-human primates provide insights about HML10 proviruses structure and diffusion 2.568
Chalcones as novel dual inhibitors of HIV-1 reverse transcriptase 2.450
Structure-Activity Relationship of Pyrrolyl Diketo Acid Derivatives as Dual Inhibitors of HIV-1 Integrase and Reverse Transcriptase Ribonuclease H Domain 2.421
Inhibition of HIV-1 reverse transcriptase associated activities by the hydroalcoholic extract of Casimiroa edulis seeds 2.415
Validation of a computed radiography device to monitor the HIV-1 RNase H activity 2.400
An efficient route to novel uracil-based drug-like molecules 2.367
Inhibitory effect of 2,3,5,6-tetrafluoro-4-[4-(Aryl)-1H-1,2,3-triazol-1-yl]benzenesulfonamide derivatives on HIV reverse transcriptase associated rnase H activities 2.352
Improvement of the activity of the anti-HIV-1 integrase aptamer T30175 by introducing a modified thymidine into the loops 2.337
A Luciferase Reporter Gene Assay to Measure Ebola Virus Viral Protein 35–Associated Inhibition of Double-Stranded RNA–Stimulated, Retinoic Acid–Inducible Gene 1–Mediated Induction of Interferon β 2.305
2-(Arylamino)-6-(trifluoromethyl)nicotinic Acid Derivatives: New HIV-1 RT Dual Inhibitors Active on Viral Replication 2.256
Exploring new scaffolds for the inibition of the Ribonuclease H function of RT HIV-1 2.255
Development and identification of a novel anti-HIV-1 peptide derived by modification of the N-terminal domain of HIV-1 integrase 2.221
Investigation on the sucrose binding pocket of HIV-1 Integrase by molecular dynamics and synergy experiments 2.213
Design and synthesis of new Isatin derivatives as HIV-1 Reverse Transcriptase associated Ribonuclease H inhibitors twenty-fourth 2.144
Isatin derivatives as new scaffolds for HIV-1 reverse transcriptase associated RNase H and RDDP dual inhibitors 2.132
Discovery of dihydroxyindole-2-carboxylic acid derivatives as dual allosteric HIV-1 Integrase and Reverse Transcriptase associated Ribonuclease H inhibitors 2.128
Targeting HIV-1 RNase H: N'-(2-Hydroxy-benzylidene)-3,4,5-Trihydroxybenzoylhydrazone as Selective Inhibitor Active against NNRTIs-Resistant Variants 2.101
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases 2.099
Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach 2.074
Kuwanon-L as a new allosteric HIV-1 integrase inhibitor: molecular modeling and biological evaluation 2.072
Design, synthesis and biolgical activity evaluation of new HIV-1 reverse transcriptase dual inhibitors 2.068
6-(1-Benzyl-1H-pyrrol-2-yl)-2,4-dioxo-5-hexenoic acids as dual inhibitors of recombinant HIV-1 integrase and ribonuclease H, synthesized by a parallel synthesis approach 2.035
Design, synthesis and biological activity evaluation of new HIV-1 reverse transcriptase dual inhibitors 1.962
DHFR Inhibitors Display a Pleiotropic Anti-Viral Activity against SARS-CoV-2: Insights into the Mechanisms of Action 1.878
Design of new inhibitors of the HIV-1 Reverse Transcriptase associated Ribonuclease H function: a synthetic approach 1.876
Pyrrolyl Pyrazoles as Non-Diketo Acid Inhibitors of the HIV-1 Ribonuclease H Function of Reverse Transcriptase 1.870
null 1.851
Scaffold hopping and optimisation of 3’,4’-dihydroxyphenyl- containing thienopyrimidinones: synthesis of quinazolinone derivatives as novel allosteric inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H 1.827
null 1.820
Identification of new scaffolds for the inhibition of HIV-1 Reverse Transcriptase associated Ribonuclease H function by means of shape based similarity screening 1.805
SITE DIRECT MUTAGENESIS AND KINETIC STUDIES TO EXPLORE THE MECHANISM OF ACTION OF ISATIN DERIVATIVES AS HIV-1 REVERSE TRANSCRIPTASE DUAL INHIBITORS 1.792
The traditional Chinese medicine plant Schisandra Chinensis as source of new HIV-1 reverse transcriptase inhibitor scaffolds effective also on non-nucleoside resistant reverse transcriptases 1.791
Inhibition of HIV-1 Ribonuclease H activity by novel frangula-emodine derivatives 1.749
HIV-1 inhibiting activity of the essential oil of Ridolfia segetum and Oenanthe crocata 1.747
New anthraquinone derivatives as inhibitors of the HIV-1 reverse transcriptase-associated ribonuclease H function 1.718
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and Ribonuclease H activities effective also on non-nucleoside resistant RTs 1.703
dsRNA binding characterization of full length recombinant wild type and mutants Zaire ebolavirus VP35 1.699
Exploring new scaffolds for the inhibition of the Ribonuclease H function of RT HIV-1 1.699
Synthesis and biological evaluation of new dual inhibitors of HIV-1 associated functions 1.608
Effects of new quinizarin derivatives on both HCV NS5B RNA polymerase and HIV-1 reverse transcriptase associated ribonuclease H activities 1.605
Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen 1.583
Development of a Raltegravir-based Photoaffinity-Labeled Probe for Human Immunodeficiency Virus-1 Integrase Capture 1.553
From classic to innovative approaches in HIV-1 infection treatment 1.551
Anti-HIV-1 activity of compounds isolated from Hypericum hircinum. 1.542
Identification of highly conserved residues involved in inhibition of HIV-1 RNase H function by Diketo acid derivatives 1.532
Probing the importance of the g-quadruplex grooves for the activity of the anti-hiv-integrase aptamer t30923 1.477
A Homogeneous Time Resolved Fluorescence (HTRF) method for the evaluation of HIV-1 integrase dimerization, enzyme reactions and interaction with LEDGF/p75 1.453
Can the ever-promising target HIV reverse transcriptase-associated RNase H become a success story for drug development? 1.434
Shape based computer aided similarity screening: a valid tool in the discovery of new scaffolds for the inhibition of HIV-1 reverse transcriptase associated ribonuclease H function 1.421
Effect of Non-nucleoside Reverse Transcriptase Inhibitors on the HIV-1 Reverse Transcriptase Associated Ribonuclease-H Activity 1.383
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase (RT) -associated DNA polymerase and Ribonuclease H (RNase H) activities effective also on the RNase H activity of non-nucleoside resistant RTs 1.368
Natural Compounds Inhibit SARS-CoV-2 nsp13 Unwinding and ATPase Enzyme Activities 1.297
null 1.214
Cytopathic SARS-CoV-2 screening on VERO-E6 cells in a large-scale repurposing effort 1.212
Exploring new scaffolds for the dual inhibition of HIV-1 RT polymerase and ribonuclease associated functions 1.190
A combined shape-, 2D-fingerprint-and pharmacophore-based virtual screening for the identification of dual inhibitors targeting HIV-1 reverse transcriptase. 1.172
HIV-1 reverse transcriptase and K562 cell replication inhibition by Ridolfia segetum (L.) Moris essential oil 1.150
A combined cell based and site directed mutagenesis approach defines highly conserved residues involved in the selective inhibition of the HIV-1 ribonuclease H function by diketoacid derivatives 1.136
In Vitro Anti-HIV-1 Reverse Transcriptase and Integrase Properties of Punica granatum L. Leaves, Bark, and Peel Extracts and Their Main Compounds 1.116
Strigolactones as broad-spectrum antivirals against β-coronaviruses through targeting the main protease Mpro 1.089
Purification and functional characterization of the full length recombinant Ebola virus VP35 protein expressed in E. coli 1.053
Past and future. Current drugs targeting HIV-1 integrase and reverse transcriptase-associated ribonuclease H activity: single and dual active site inhibitors 1.042
Quinolinonyl Non-Diketo Acid Derivatives as Inhibitors of HIV-1 Ribonuclease H and Polymerase Functions of Reverse Transcriptase 980
Development of 3-hydroxyquinolein-2(1H)-ones as inhibitors of HIV-1 integrase and ribonuclease H function of reverse transcriptase 975
Totale 238.071
Categoria #
all - tutte 311.124
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 311.124


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20218.709 0 0 0 0 0 0 0 0 0 3.344 3.907 1.458
2021/202213.416 1.338 1.020 642 772 1.064 1.094 720 579 1.260 1.273 1.812 1.842
2022/202321.107 1.698 2.901 2.540 2.044 1.399 2.491 1.086 1.683 1.162 1.243 1.870 990
2023/202420.613 905 749 1.251 1.736 2.153 3.614 2.934 1.418 986 1.195 1.758 1.914
2024/202544.636 10.914 13.148 6.932 4.236 1.988 2.388 3.362 145 411 305 323 484
2025/20269.261 704 353 1.285 918 938 730 1.638 983 736 976 0 0
Totale 260.643