UNICA IRIS Institutional Research Information System

ESPOSITO, FRANCESCA
 Distribuzione geografica
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Continente #
EU - Europa 242.654
NA - Nord America 8.816
AS - Asia 3.501
SA - Sud America 595
AF - Africa 114
Continente sconosciuto - Info sul continente non disponibili 10
OC - Oceania 7
Totale 255.697
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Nazione #
IT - Italia 240.463
US - Stati Uniti d'America 8.699
CN - Cina 1.437
SG - Singapore 1.342
SE - Svezia 594
UA - Ucraina 594
BR - Brasile 480
DE - Germania 315
VN - Vietnam 216
FI - Finlandia 192
GB - Regno Unito 174
FR - Francia 92
IN - India 90
KR - Corea 86
CA - Canada 83
HK - Hong Kong 59
AR - Argentina 54
MA - Marocco 47
NL - Olanda 42
TR - Turchia 38
JP - Giappone 37
PL - Polonia 37
ZA - Sudafrica 31
AT - Austria 30
BD - Bangladesh 30
MX - Messico 24
IQ - Iraq 23
PK - Pakistan 23
ES - Italia 22
BE - Belgio 20
EC - Ecuador 19
ID - Indonesia 18
RU - Federazione Russa 17
UZ - Uzbekistan 15
IR - Iran 14
IE - Irlanda 13
VE - Venezuela 13
TW - Taiwan 10
AZ - Azerbaigian 9
CO - Colombia 8
CZ - Repubblica Ceca 8
EG - Egitto 8
EU - Europa 8
TN - Tunisia 8
KE - Kenya 7
NP - Nepal 7
DZ - Algeria 6
JO - Giordania 6
NO - Norvegia 6
PE - Perù 6
SA - Arabia Saudita 6
AU - Australia 5
CH - Svizzera 5
GE - Georgia 5
IL - Israele 5
LV - Lettonia 5
AE - Emirati Arabi Uniti 4
BO - Bolivia 4
CL - Cile 4
KG - Kirghizistan 4
LT - Lituania 4
PT - Portogallo 4
DK - Danimarca 3
DO - Repubblica Dominicana 3
GR - Grecia 3
LB - Libano 3
LU - Lussemburgo 3
PH - Filippine 3
PY - Paraguay 3
UY - Uruguay 3
A1 - Anonimo 2
AM - Armenia 2
CR - Costa Rica 2
HR - Croazia 2
HU - Ungheria 2
KZ - Kazakistan 2
MU - Mauritius 2
NZ - Nuova Zelanda 2
TH - Thailandia 2
TT - Trinidad e Tobago 2
AL - Albania 1
AO - Angola 1
BG - Bulgaria 1
CG - Congo 1
CI - Costa d'Avorio 1
GP - Guadalupe 1
HN - Honduras 1
LK - Sri Lanka 1
MY - Malesia 1
NG - Nigeria 1
NI - Nicaragua 1
OM - Oman 1
RO - Romania 1
SI - Slovenia 1
SR - Suriname 1
SY - Repubblica araba siriana 1
TJ - Tagikistan 1
ZW - Zimbabwe 1
Totale 255.697
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Città #
Cagliari 234.606
Uta 5.175
Fairfield 825
Ashburn 806
Woodbridge 764
Singapore 593
Chandler 541
Dallas 534
Houston 419
Nyköping 418
Boardman 382
Seattle 365
Wilmington 361
Ann Arbor 352
Beijing 323
Cambridge 304
Jacksonville 286
New York 249
Dearborn 198
Los Angeles 151
Santa Clara 133
Shanghai 125
Nanjing 118
Boston 107
Hefei 103
The Dalles 103
Seoul 81
Helsinki 79
Dong Ket 69
Redwood City 64
Buffalo 61
Munich 55
Hong Kong 54
Ho Chi Minh City 52
Rome 51
San Diego 49
Milan 43
Redondo Beach 41
Herndon 40
Casablanca 36
Nanchang 36
São Paulo 36
Guangzhou 33
Mountain View 31
Warsaw 31
Changsha 29
Shenyang 29
Tokyo 29
Atlanta 28
Toronto 27
Tianjin 26
Chicago 25
London 25
Hanoi 24
Hebei 24
Rio de Janeiro 22
Amsterdam 21
Montreal 20
Jiaxing 19
Orange 19
Hangzhou 18
Frankfurt am Main 17
Ottawa 17
Phoenix 17
Vienna 17
Washington 17
Brooklyn 16
Norwalk 16
Sassari 16
Turku 16
Istanbul 15
Jinan 15
Johannesburg 15
Tashkent 15
Wuhan 15
Nuremberg 14
Pune 14
Stockholm 14
Verona 14
Brussels 13
San Francisco 13
Chennai 12
Kunming 12
Zhengzhou 12
Denver 11
Dublin 11
Guayaquil 11
Lappeenranta 11
Mumbai 11
Poplar 11
Curitiba 10
Paris 10
Baku 9
Columbus 9
Falls Church 9
Jakarta 9
Napoli 9
Asnières-sur-Seine 8
Auburn Hills 8
Baghdad 8
Totale 250.165
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Nome #
(3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro- 1H -indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase 14.693
Design, synthesis, and biological evaluation of 1,3-diarylpropenones as dual inhibitors of HIV-1 reverse transcriptase 4.486
Biological activities of aerial parts extracts of Euphorbia characias 4.395
Ribonuclease H/DNA polymerase HIV-1 reverse transcriptase dual inhibitor: mechanistic studies on the allosteric mode of action of isatin-based compound RMNC6 4.293
Identification of Myricetin as Ebolavirus VP35-dsRNA interaction inhibitor through a novel fluorescence-based assay 3.711
Euphorbia characias latex: Micromorphology of rubber particles and rubber transferase activity 3.643
Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 Reverse transcriptase-associated RNase H and RDDP functions 3.486
Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach 3.436
Dual HIV-1 reverse transcriptase and integrase inhibitors from Limonium morisianum Arrigoni, an endemic species of Sardinia (Italy) 3.406
Sennoside A, derived from the traditional chinese medicine plant Rheum L., is a new dual HIV-1 inhibitor effective on HIV-1 replication 3.397
Design and synthesis of new isatin derivatives as HIV-1 reverse transcriptase associated ribonuclease H inhibitors 3.287
Studies on Cycloheptathiophene-3-carboxamide Derivatives as Allosteric HIV-1 Ribonuclease H Inhibitors 3.267
Multi-target activity of Hemidesmus indicus decoction against innovative HIV-1 drug targets and characterization of Lupeol mode of action 3.263
New insights into the operative network of FaEO, an enone oxidoreductase from Fragaria x ananassa Duch 3.084
S-layer proteins as a source of carotenoids: Isolation of the carotenoid cofactor deinoxanthin from its S-layer protein DR_2577 3.071
Inhibition of HIV-1 reverse transcriptase dimerization by small molecules 3.046
Prenylated phloroglucinols from Hypericum scruglii, an endemic species of Sardinia (Italy), as new dual HIV-1 inhibitors effective on HIV-1 replication 3.023
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Dual Inhibitors of HIV-1 RT. 3.005
Onopordum illyricum L., a Mediterranean plant, as a source of anti HIV-1 compounds 2.968
Purification and characterization of DR_2577 (SlpA) a major S-layer protein from Deinococcus radiodurans 2.940
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) enlighten the mechanism of action of a new Ribonuclease H/DNA polymerase RT dual inhibitor 2.935
Preliminary study of endemic plants of Sardinia as a source of new antiviral agents 2.892
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Single Site Dual Inhibitors of HIV-1 RT 2.882
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) shed light on the mechanism of action of a new Ribonuclease H/ DNA polymerase RT dual inhibitor 2.870
Structure-guided approach identifies a novel class of HIV-1 Ribonuclease H inhibitors: Binding mode insights through magnesium complexation and site-directed mutagenesis studies 2.864
Chelation motifs affecting metal-dependent viral enzymes: N′-acylhydrazone ligands as dual target inhibitors of HIV-1 Integrase and Reverse Transcriptase Ribonuclease H domain 2.850
Hypericum hircinum L. components as new single-molecule inhibitors of both HIV-1 reverse transcriptase-associated DNA polymerase and ribonuclease H activities 2.841
From the traditional Chinese medicine plant Schisandra chinensis new scaffolds effective on HIV-1 reverse transcriptase resistant to non-nucleoside inhibitors 2.835
On the S-layer of Thermus thermophilus and the assembling of its main protein SIpA 2.823
Natural Product Kuwanon-L Inhibits HIV-1 Replication through Multiple Target Binding 2.794
RhVI1 is a membrane-anchored vacuolar invertase highly expressed in Rosa hybrida L. petals 2.791
Mutagenic study on HIV-1 reverse transcriptase to explore the mechanism of action of HIV-1 reverse transcriptase dual inhibitors 2.738
null 2.719
Chromenone derivatives as a versatile scaffold with dual mode of inhibition of HIV-1 reverse transcriptase-associated Ribonuclease H function and integrase activity 2.701
New insights into the interaction between pyrrolyl diketoacids and HIV-1 integrase active site and comparison with RNase H 2.684
3-[2-(4-aryl-1,3-thiazol-2-yl)hydrazin-1-ylidene]-1H-indol-2-ones as new potential dual inhibitors of polimerase and ribonuclease HIV-1 RT associated function 2.580
Identification of a novel HERV-K(HML10): comprehensive characterization and comparative analysis in non-human primates provide insights about HML10 proviruses structure and diffusion 2.538
Chalcones as novel dual inhibitors of HIV-1 reverse transcriptase 2.419
Inhibition of HIV-1 reverse transcriptase associated activities by the hydroalcoholic extract of Casimiroa edulis seeds 2.389
Structure-Activity Relationship of Pyrrolyl Diketo Acid Derivatives as Dual Inhibitors of HIV-1 Integrase and Reverse Transcriptase Ribonuclease H Domain 2.368
Validation of a computed radiography device to monitor the HIV-1 RNase H activity 2.365
An efficient route to novel uracil-based drug-like molecules 2.342
Improvement of the activity of the anti-HIV-1 integrase aptamer T30175 by introducing a modified thymidine into the loops 2.317
Inhibitory effect of 2,3,5,6-tetrafluoro-4-[4-(Aryl)-1H-1,2,3-triazol-1-yl]benzenesulfonamide derivatives on HIV reverse transcriptase associated rnase H activities 2.313
A Luciferase Reporter Gene Assay to Measure Ebola Virus Viral Protein 35–Associated Inhibition of Double-Stranded RNA–Stimulated, Retinoic Acid–Inducible Gene 1–Mediated Induction of Interferon β 2.282
Exploring new scaffolds for the inibition of the Ribonuclease H function of RT HIV-1 2.230
2-(Arylamino)-6-(trifluoromethyl)nicotinic Acid Derivatives: New HIV-1 RT Dual Inhibitors Active on Viral Replication 2.230
Investigation on the sucrose binding pocket of HIV-1 Integrase by molecular dynamics and synergy experiments 2.200
Development and identification of a novel anti-HIV-1 peptide derived by modification of the N-terminal domain of HIV-1 integrase 2.194
Design and synthesis of new Isatin derivatives as HIV-1 Reverse Transcriptase associated Ribonuclease H inhibitors twenty-fourth 2.125
Discovery of dihydroxyindole-2-carboxylic acid derivatives as dual allosteric HIV-1 Integrase and Reverse Transcriptase associated Ribonuclease H inhibitors 2.101
Isatin derivatives as new scaffolds for HIV-1 reverse transcriptase associated RNase H and RDDP dual inhibitors 2.100
Targeting HIV-1 RNase H: N'-(2-Hydroxy-benzylidene)-3,4,5-Trihydroxybenzoylhydrazone as Selective Inhibitor Active against NNRTIs-Resistant Variants 2.066
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases 2.063
Design, synthesis and biolgical activity evaluation of new HIV-1 reverse transcriptase dual inhibitors 2.046
Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach 2.039
Kuwanon-L as a new allosteric HIV-1 integrase inhibitor: molecular modeling and biological evaluation 2.039
6-(1-Benzyl-1H-pyrrol-2-yl)-2,4-dioxo-5-hexenoic acids as dual inhibitors of recombinant HIV-1 integrase and ribonuclease H, synthesized by a parallel synthesis approach 2.010
Design, synthesis and biological activity evaluation of new HIV-1 reverse transcriptase dual inhibitors 1.930
null 1.851
Design of new inhibitors of the HIV-1 Reverse Transcriptase associated Ribonuclease H function: a synthetic approach 1.850
DHFR Inhibitors Display a Pleiotropic Anti-Viral Activity against SARS-CoV-2: Insights into the Mechanisms of Action 1.847
Pyrrolyl Pyrazoles as Non-Diketo Acid Inhibitors of the HIV-1 Ribonuclease H Function of Reverse Transcriptase 1.836
null 1.820
Scaffold hopping and optimisation of 3’,4’-dihydroxyphenyl- containing thienopyrimidinones: synthesis of quinazolinone derivatives as novel allosteric inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H 1.782
Identification of new scaffolds for the inhibition of HIV-1 Reverse Transcriptase associated Ribonuclease H function by means of shape based similarity screening 1.770
SITE DIRECT MUTAGENESIS AND KINETIC STUDIES TO EXPLORE THE MECHANISM OF ACTION OF ISATIN DERIVATIVES AS HIV-1 REVERSE TRANSCRIPTASE DUAL INHIBITORS 1.759
The traditional Chinese medicine plant Schisandra Chinensis as source of new HIV-1 reverse transcriptase inhibitor scaffolds effective also on non-nucleoside resistant reverse transcriptases 1.758
HIV-1 inhibiting activity of the essential oil of Ridolfia segetum and Oenanthe crocata 1.719
Inhibition of HIV-1 Ribonuclease H activity by novel frangula-emodine derivatives 1.706
New anthraquinone derivatives as inhibitors of the HIV-1 reverse transcriptase-associated ribonuclease H function 1.684
dsRNA binding characterization of full length recombinant wild type and mutants Zaire ebolavirus VP35 1.673
Exploring new scaffolds for the inhibition of the Ribonuclease H function of RT HIV-1 1.671
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and Ribonuclease H activities effective also on non-nucleoside resistant RTs 1.666
Effects of new quinizarin derivatives on both HCV NS5B RNA polymerase and HIV-1 reverse transcriptase associated ribonuclease H activities 1.588
Synthesis and biological evaluation of new dual inhibitors of HIV-1 associated functions 1.580
Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen 1.544
Development of a Raltegravir-based Photoaffinity-Labeled Probe for Human Immunodeficiency Virus-1 Integrase Capture 1.536
Anti-HIV-1 activity of compounds isolated from Hypericum hircinum. 1.524
From classic to innovative approaches in HIV-1 infection treatment 1.524
Identification of highly conserved residues involved in inhibition of HIV-1 RNase H function by Diketo acid derivatives 1.512
Probing the importance of the g-quadruplex grooves for the activity of the anti-hiv-integrase aptamer t30923 1.454
A Homogeneous Time Resolved Fluorescence (HTRF) method for the evaluation of HIV-1 integrase dimerization, enzyme reactions and interaction with LEDGF/p75 1.438
Can the ever-promising target HIV reverse transcriptase-associated RNase H become a success story for drug development? 1.415
Shape based computer aided similarity screening: a valid tool in the discovery of new scaffolds for the inhibition of HIV-1 reverse transcriptase associated ribonuclease H function 1.383
Effect of Non-nucleoside Reverse Transcriptase Inhibitors on the HIV-1 Reverse Transcriptase Associated Ribonuclease-H Activity 1.359
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase (RT) -associated DNA polymerase and Ribonuclease H (RNase H) activities effective also on the RNase H activity of non-nucleoside resistant RTs 1.334
Natural Compounds Inhibit SARS-CoV-2 nsp13 Unwinding and ATPase Enzyme Activities 1.255
null 1.214
Cytopathic SARS-CoV-2 screening on VERO-E6 cells in a large-scale repurposing effort 1.171
Exploring new scaffolds for the dual inhibition of HIV-1 RT polymerase and ribonuclease associated functions 1.143
HIV-1 reverse transcriptase and K562 cell replication inhibition by Ridolfia segetum (L.) Moris essential oil 1.132
A combined shape-, 2D-fingerprint-and pharmacophore-based virtual screening for the identification of dual inhibitors targeting HIV-1 reverse transcriptase. 1.131
A combined cell based and site directed mutagenesis approach defines highly conserved residues involved in the selective inhibition of the HIV-1 ribonuclease H function by diketoacid derivatives 1.107
In Vitro Anti-HIV-1 Reverse Transcriptase and Integrase Properties of Punica granatum L. Leaves, Bark, and Peel Extracts and Their Main Compounds 1.079
Strigolactones as broad-spectrum antivirals against β-coronaviruses through targeting the main protease Mpro 1.050
Purification and functional characterization of the full length recombinant Ebola virus VP35 protein expressed in E. coli 1.036
Past and future. Current drugs targeting HIV-1 integrase and reverse transcriptase-associated ribonuclease H activity: single and dual active site inhibitors 1.028
Quinolinonyl Non-Diketo Acid Derivatives as Inhibitors of HIV-1 Ribonuclease H and Polymerase Functions of Reverse Transcriptase 950
Development of 3-hydroxyquinolein-2(1H)-ones as inhibitors of HIV-1 integrase and ribonuclease H function of reverse transcriptase 945
Totale 235.229
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Categoria #
all - tutte 305.179
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 305.179
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202123.381 0 0 0 0 0 5.582 4.220 3.507 1.363 3.344 3.907 1.458
2021/202213.416 1.338 1.020 642 772 1.064 1.094 720 579 1.260 1.273 1.812 1.842
2022/202321.107 1.698 2.901 2.540 2.044 1.399 2.491 1.086 1.683 1.162 1.243 1.870 990
2023/202420.613 905 749 1.251 1.736 2.153 3.614 2.934 1.418 986 1.195 1.758 1.914
2024/202544.636 10.914 13.148 6.932 4.236 1.988 2.388 3.362 145 411 305 323 484
2025/20264.860 704 353 1.285 918 938 662 0 0 0 0 0 0
Totale 256.242