ESPOSITO, FRANCESCA
 Distribuzione geografica
Continente #
EU - Europa 236.841
NA - Nord America 7.093
AS - Asia 1.180
SA - Sud America 23
AF - Africa 22
Continente sconosciuto - Info sul continente non disponibili 10
OC - Oceania 7
Totale 245.176
Nazione #
IT - Italia 235.054
US - Stati Uniti d'America 7.042
CN - Cina 713
UA - Ucraina 582
SE - Svezia 546
DE - Germania 233
SG - Singapore 224
FI - Finlandia 164
GB - Regno Unito 121
VN - Vietnam 72
FR - Francia 47
CA - Canada 46
IN - India 46
KR - Corea 26
HK - Hong Kong 20
TR - Turchia 17
BE - Belgio 13
IR - Iran 13
NL - Olanda 13
BR - Brasile 12
PK - Pakistan 12
PL - Polonia 11
ES - Italia 8
EU - Europa 8
JP - Giappone 8
IE - Irlanda 7
AR - Argentina 6
CZ - Repubblica Ceca 6
ID - Indonesia 6
IQ - Iraq 6
ZA - Sudafrica 6
AT - Austria 5
AU - Australia 5
RU - Federazione Russa 5
CH - Svizzera 4
LV - Lettonia 4
NO - Norvegia 4
TN - Tunisia 4
TW - Taiwan 4
CL - Cile 3
DZ - Algeria 3
EG - Egitto 3
GR - Grecia 3
MA - Marocco 3
MX - Messico 3
PT - Portogallo 3
A1 - Anonimo 2
AE - Emirati Arabi Uniti 2
HR - Croazia 2
HU - Ungheria 2
IL - Israele 2
LU - Lussemburgo 2
MU - Mauritius 2
NZ - Nuova Zelanda 2
SA - Arabia Saudita 2
TH - Thailandia 2
AZ - Azerbaigian 1
CI - Costa d'Avorio 1
CO - Colombia 1
CR - Costa Rica 1
DO - Repubblica Dominicana 1
EC - Ecuador 1
KG - Kirghizistan 1
PH - Filippine 1
RO - Romania 1
SI - Slovenia 1
TJ - Tagikistan 1
UZ - Uzbekistan 1
Totale 245.176
Città #
Cagliari 229.364
Uta 5.081
Fairfield 825
Woodbridge 764
Chandler 541
Ashburn 477
Nyköping 418
Houston 416
Boardman 382
Seattle 360
Wilmington 359
Ann Arbor 352
Cambridge 304
Jacksonville 286
New York 218
Dearborn 198
Singapore 128
Shanghai 122
Nanjing 118
Santa Clara 114
Boston 91
Beijing 88
Helsinki 76
Dong Ket 69
Redwood City 64
San Diego 48
Los Angeles 41
Herndon 40
Milan 40
Rome 39
Nanchang 33
Mountain View 31
Guangzhou 28
Shenyang 28
Changsha 24
Hebei 24
Toronto 22
Seoul 21
Jiaxing 19
Orange 19
Atlanta 17
Ottawa 17
Hong Kong 16
London 16
Norwalk 16
Sassari 16
Tianjin 16
Jinan 15
Washington 15
Verona 14
Wuhan 14
Brussels 13
Pune 13
Hangzhou 12
Istanbul 12
Kunming 11
Phoenix 11
Munich 10
Zhengzhou 10
Falls Church 9
Napoli 9
Paris 9
Auburn Hills 8
Warsaw 8
Hefei 7
Naples 7
Redmond 7
Amsterdam 6
Dublin 6
Gujranwala 6
Jinhua 6
Menlo Park 6
Millbury 6
Mumbai 6
Ningbo 6
Siracusa 6
Chicago 5
Frankfurt am Main 5
Indiana 5
Kilburn 5
Piscataway 5
Quartu Sant'Elena 5
San Martín de los Andes 5
Vienna 5
Wuxi 5
Antea 4
Bari 4
Bengaluru 4
Carbonia 4
Chiswick 4
Cosenza 4
Hyderabad 4
Jakarta 4
Nanning 4
Oslo 4
Padova 4
Quartu Sant'elena 4
Rockville 4
San Francisco 4
Serramanna 4
Totale 242.159
Nome #
(3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro- 1H -indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase 14.610
Design, synthesis, and biological evaluation of 1,3-diarylpropenones as dual inhibitors of HIV-1 reverse transcriptase 4.377
Biological activities of aerial parts extracts of Euphorbia characias 4.325
Ribonuclease H/DNA polymerase HIV-1 reverse transcriptase dual inhibitor: mechanistic studies on the allosteric mode of action of isatin-based compound RMNC6 4.228
Identification of Myricetin as Ebolavirus VP35-dsRNA interaction inhibitor through a novel fluorescence-based assay 3.616
Euphorbia characias latex: Micromorphology of rubber particles and rubber transferase activity 3.580
Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 Reverse transcriptase-associated RNase H and RDDP functions 3.399
Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach 3.359
Sennoside A, derived from the traditional chinese medicine plant Rheum L., is a new dual HIV-1 inhibitor effective on HIV-1 replication 3.332
Dual HIV-1 reverse transcriptase and integrase inhibitors from Limonium morisianum Arrigoni, an endemic species of Sardinia (Italy) 3.328
Multi-target activity of Hemidesmus indicus decoction against innovative HIV-1 drug targets and characterization of Lupeol mode of action 3.212
Design and synthesis of new isatin derivatives as HIV-1 reverse transcriptase associated ribonuclease H inhibitors 3.206
Studies on Cycloheptathiophene-3-carboxamide Derivatives as Allosteric HIV-1 Ribonuclease H Inhibitors 3.194
New insights into the operative network of FaEO, an enone oxidoreductase from Fragaria x ananassa Duch 3.026
S-layer proteins as a source of carotenoids: Isolation of the carotenoid cofactor deinoxanthin from its S-layer protein DR_2577 3.009
Inhibition of HIV-1 reverse transcriptase dimerization by small molecules 2.984
Prenylated phloroglucinols from Hypericum scruglii, an endemic species of Sardinia (Italy), as new dual HIV-1 inhibitors effective on HIV-1 replication 2.947
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Dual Inhibitors of HIV-1 RT. 2.937
Onopordum illyricum L., a Mediterranean plant, as a source of anti HIV-1 compounds 2.869
Purification and characterization of DR_2577 (SlpA) a major S-layer protein from Deinococcus radiodurans 2.868
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) enlighten the mechanism of action of a new Ribonuclease H/DNA polymerase RT dual inhibitor 2.858
Preliminary study of endemic plants of Sardinia as a source of new antiviral agents 2.821
Structure-guided approach identifies a novel class of HIV-1 Ribonuclease H inhibitors: Binding mode insights through magnesium complexation and site-directed mutagenesis studies 2.819
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) shed light on the mechanism of action of a new Ribonuclease H/ DNA polymerase RT dual inhibitor 2.813
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Single Site Dual Inhibitors of HIV-1 RT 2.798
Chelation motifs affecting metal-dependent viral enzymes: N′-acylhydrazone ligands as dual target inhibitors of HIV-1 Integrase and Reverse Transcriptase Ribonuclease H domain 2.775
From the traditional Chinese medicine plant Schisandra chinensis new scaffolds effective on HIV-1 reverse transcriptase resistant to non-nucleoside inhibitors 2.774
Hypericum hircinum L. components as new single-molecule inhibitors of both HIV-1 reverse transcriptase-associated DNA polymerase and ribonuclease H activities 2.773
On the S-layer of Thermus thermophilus and the assembling of its main protein SIpA 2.734
Natural Product Kuwanon-L Inhibits HIV-1 Replication through Multiple Target Binding 2.721
null 2.719
RhVI1 is a membrane-anchored vacuolar invertase highly expressed in Rosa hybrida L. petals 2.704
Mutagenic study on HIV-1 reverse transcriptase to explore the mechanism of action of HIV-1 reverse transcriptase dual inhibitors 2.666
Chromenone derivatives as a versatile scaffold with dual mode of inhibition of HIV-1 reverse transcriptase-associated Ribonuclease H function and integrase activity 2.627
New insights into the interaction between pyrrolyl diketoacids and HIV-1 integrase active site and comparison with RNase H 2.602
3-[2-(4-aryl-1,3-thiazol-2-yl)hydrazin-1-ylidene]-1H-indol-2-ones as new potential dual inhibitors of polimerase and ribonuclease HIV-1 RT associated function 2.520
Identification of a novel HERV-K(HML10): comprehensive characterization and comparative analysis in non-human primates provide insights about HML10 proviruses structure and diffusion 2.464
Chalcones as novel dual inhibitors of HIV-1 reverse transcriptase 2.349
Inhibition of HIV-1 reverse transcriptase associated activities by the hydroalcoholic extract of Casimiroa edulis seeds 2.308
Structure-Activity Relationship of Pyrrolyl Diketo Acid Derivatives as Dual Inhibitors of HIV-1 Integrase and Reverse Transcriptase Ribonuclease H Domain 2.296
Validation of a computed radiography device to monitor the HIV-1 RNase H activity 2.287
An efficient route to novel uracil-based drug-like molecules 2.287
Improvement of the activity of the anti-HIV-1 integrase aptamer T30175 by introducing a modified thymidine into the loops 2.253
Inhibitory effect of 2,3,5,6-tetrafluoro-4-[4-(Aryl)-1H-1,2,3-triazol-1-yl]benzenesulfonamide derivatives on HIV reverse transcriptase associated rnase H activities 2.243
A Luciferase Reporter Gene Assay to Measure Ebola Virus Viral Protein 35–Associated Inhibition of Double-Stranded RNA–Stimulated, Retinoic Acid–Inducible Gene 1–Mediated Induction of Interferon β 2.215
Exploring new scaffolds for the inibition of the Ribonuclease H function of RT HIV-1 2.167
2-(Arylamino)-6-(trifluoromethyl)nicotinic Acid Derivatives: New HIV-1 RT Dual Inhibitors Active on Viral Replication 2.145
Development and identification of a novel anti-HIV-1 peptide derived by modification of the N-terminal domain of HIV-1 integrase 2.107
Investigation on the sucrose binding pocket of HIV-1 Integrase by molecular dynamics and synergy experiments 2.107
Design and synthesis of new Isatin derivatives as HIV-1 Reverse Transcriptase associated Ribonuclease H inhibitors twenty-fourth 2.066
Isatin derivatives as new scaffolds for HIV-1 reverse transcriptase associated RNase H and RDDP dual inhibitors 2.032
Discovery of dihydroxyindole-2-carboxylic acid derivatives as dual allosteric HIV-1 Integrase and Reverse Transcriptase associated Ribonuclease H inhibitors 2.024
Design, synthesis and biolgical activity evaluation of new HIV-1 reverse transcriptase dual inhibitors 1.986
Targeting HIV-1 RNase H: N'-(2-Hydroxy-benzylidene)-3,4,5-Trihydroxybenzoylhydrazone as Selective Inhibitor Active against NNRTIs-Resistant Variants 1.980
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases 1.979
Kuwanon-L as a new allosteric HIV-1 integrase inhibitor: molecular modeling and biological evaluation 1.964
Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach 1.942
6-(1-Benzyl-1H-pyrrol-2-yl)-2,4-dioxo-5-hexenoic acids as dual inhibitors of recombinant HIV-1 integrase and ribonuclease H, synthesized by a parallel synthesis approach 1.913
Design, synthesis and biological activity evaluation of new HIV-1 reverse transcriptase dual inhibitors 1.874
null 1.851
null 1.820
Design of new inhibitors of the HIV-1 Reverse Transcriptase associated Ribonuclease H function: a synthetic approach 1.790
Pyrrolyl Pyrazoles as Non-Diketo Acid Inhibitors of the HIV-1 Ribonuclease H Function of Reverse Transcriptase 1.780
DHFR Inhibitors Display a Pleiotropic Anti-Viral Activity against SARS-CoV-2: Insights into the Mechanisms of Action 1.768
Identification of new scaffolds for the inhibition of HIV-1 Reverse Transcriptase associated Ribonuclease H function by means of shape based similarity screening 1.716
The traditional Chinese medicine plant Schisandra Chinensis as source of new HIV-1 reverse transcriptase inhibitor scaffolds effective also on non-nucleoside resistant reverse transcriptases 1.703
SITE DIRECT MUTAGENESIS AND KINETIC STUDIES TO EXPLORE THE MECHANISM OF ACTION OF ISATIN DERIVATIVES AS HIV-1 REVERSE TRANSCRIPTASE DUAL INHIBITORS 1.681
Scaffold hopping and optimisation of 3’,4’-dihydroxyphenyl- containing thienopyrimidinones: synthesis of quinazolinone derivatives as novel allosteric inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H 1.679
HIV-1 inhibiting activity of the essential oil of Ridolfia segetum and Oenanthe crocata 1.640
Inhibition of HIV-1 Ribonuclease H activity by novel frangula-emodine derivatives 1.628
New anthraquinone derivatives as inhibitors of the HIV-1 reverse transcriptase-associated ribonuclease H function 1.621
Exploring new scaffolds for the inhibition of the Ribonuclease H function of RT HIV-1 1.616
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and Ribonuclease H activities effective also on non-nucleoside resistant RTs 1.600
dsRNA binding characterization of full length recombinant wild type and mutants Zaire ebolavirus VP35 1.573
Synthesis and biological evaluation of new dual inhibitors of HIV-1 associated functions 1.527
Effects of new quinizarin derivatives on both HCV NS5B RNA polymerase and HIV-1 reverse transcriptase associated ribonuclease H activities 1.490
Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen 1.473
From classic to innovative approaches in HIV-1 infection treatment 1.467
Anti-HIV-1 activity of compounds isolated from Hypericum hircinum. 1.461
Development of a Raltegravir-based Photoaffinity-Labeled Probe for Human Immunodeficiency Virus-1 Integrase Capture 1.445
Identification of highly conserved residues involved in inhibition of HIV-1 RNase H function by Diketo acid derivatives 1.441
Can the ever-promising target HIV reverse transcriptase-associated RNase H become a success story for drug development? 1.368
Probing the importance of the g-quadruplex grooves for the activity of the anti-hiv-integrase aptamer t30923 1.359
A Homogeneous Time Resolved Fluorescence (HTRF) method for the evaluation of HIV-1 integrase dimerization, enzyme reactions and interaction with LEDGF/p75 1.346
Shape based computer aided similarity screening: a valid tool in the discovery of new scaffolds for the inhibition of HIV-1 reverse transcriptase associated ribonuclease H function 1.329
Effect of Non-nucleoside Reverse Transcriptase Inhibitors on the HIV-1 Reverse Transcriptase Associated Ribonuclease-H Activity 1.306
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase (RT) -associated DNA polymerase and Ribonuclease H (RNase H) activities effective also on the RNase H activity of non-nucleoside resistant RTs 1.271
null 1.214
Natural Compounds Inhibit SARS-CoV-2 nsp13 Unwinding and ATPase Enzyme Activities 1.165
Cytopathic SARS-CoV-2 screening on VERO-E6 cells in a large-scale repurposing effort 1.095
A combined shape-, 2D-fingerprint-and pharmacophore-based virtual screening for the identification of dual inhibitors targeting HIV-1 reverse transcriptase. 1.064
HIV-1 reverse transcriptase and K562 cell replication inhibition by Ridolfia segetum (L.) Moris essential oil 1.055
A combined cell based and site directed mutagenesis approach defines highly conserved residues involved in the selective inhibition of the HIV-1 ribonuclease H function by diketoacid derivatives 1.041
Exploring new scaffolds for the dual inhibition of HIV-1 RT polymerase and ribonuclease associated functions 1.024
In Vitro Anti-HIV-1 Reverse Transcriptase and Integrase Properties of Punica granatum L. Leaves, Bark, and Peel Extracts and Their Main Compounds 986
Strigolactones as broad-spectrum antivirals against β-coronaviruses through targeting the main protease Mpro 949
Purification and functional characterization of the full length recombinant Ebola virus VP35 protein expressed in E. coli 938
Past and future. Current drugs targeting HIV-1 integrase and reverse transcriptase-associated ribonuclease H activity: single and dual active site inhibitors 928
Development of 3-hydroxyquinolein-2(1H)-ones as inhibitors of HIV-1 integrase and ribonuclease H function of reverse transcriptase 896
Quinolinonyl Non-Diketo Acid Derivatives as Inhibitors of HIV-1 Ribonuclease H and Polymerase Functions of Reverse Transcriptase 879
Totale 228.101
Categoria #
all - tutte 282.198
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 282.198


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202019.944 0 0 0 0 0 9.736 5.182 977 652 1.028 791 1.578
2020/202154.305 1.646 1.809 2.383 14.910 10.176 5.582 4.220 3.507 1.363 3.344 3.907 1.458
2021/202213.416 1.338 1.020 642 772 1.064 1.094 720 579 1.260 1.273 1.812 1.842
2022/202321.107 1.698 2.901 2.540 2.044 1.399 2.491 1.086 1.683 1.162 1.243 1.870 990
2023/202420.613 905 749 1.251 1.736 2.153 3.614 2.934 1.418 986 1.195 1.758 1.914
2024/202538.904 10.914 13.148 6.932 4.236 1.988 1.686 0 0 0 0 0 0
Totale 245.650