ESPOSITO, FRANCESCA
 Distribuzione geografica
Continente #
EU - Europa 245.997
NA - Nord America 10.680
AS - Asia 4.702
SA - Sud America 735
Continente sconosciuto - Info sul continente non disponibili 568
AF - Africa 168
OC - Oceania 7
Totale 262.857
Nazione #
IT - Italia 243.411
US - Stati Uniti d'America 10.511
SG - Singapore 1.802
CN - Cina 1.647
SE - Svezia 633
UA - Ucraina 599
BR - Brasile 547
VN - Vietnam 401
DE - Germania 333
FI - Finlandia 301
FR - Francia 229
GB - Regno Unito 198
HK - Hong Kong 143
IN - India 140
CA - Canada 108
KR - Corea 92
BD - Bangladesh 84
AR - Argentina 80
NL - Olanda 59
MA - Marocco 58
TR - Turchia 52
JP - Giappone 51
IQ - Iraq 50
ZA - Sudafrica 42
PK - Pakistan 41
AT - Austria 39
PL - Polonia 38
MX - Messico 35
EC - Ecuador 34
ES - Italia 32
ID - Indonesia 27
RU - Federazione Russa 23
SA - Arabia Saudita 23
BE - Belgio 21
UZ - Uzbekistan 21
VE - Venezuela 21
CO - Colombia 18
TN - Tunisia 17
IR - Iran 15
IE - Irlanda 14
KE - Kenya 13
PH - Filippine 13
EG - Egitto 11
TW - Taiwan 11
AZ - Azerbaigian 10
AE - Emirati Arabi Uniti 9
CZ - Repubblica Ceca 9
DZ - Algeria 9
JO - Giordania 9
EU - Europa 8
GE - Georgia 8
NP - Nepal 8
BO - Bolivia 7
CL - Cile 7
UY - Uruguay 7
IL - Israele 6
LV - Lettonia 6
MY - Malesia 6
NO - Norvegia 6
PE - Perù 6
AL - Albania 5
AU - Australia 5
CH - Svizzera 5
CR - Costa Rica 5
GR - Grecia 5
KG - Kirghizistan 5
LB - Libano 5
LT - Lituania 5
PT - Portogallo 5
PY - Paraguay 5
ET - Etiopia 4
HU - Ungheria 4
KZ - Kazakistan 4
NI - Nicaragua 4
RO - Romania 4
DK - Danimarca 3
DO - Repubblica Dominicana 3
JM - Giamaica 3
LU - Lussemburgo 3
MU - Mauritius 3
SV - El Salvador 3
TH - Thailandia 3
TT - Trinidad e Tobago 3
A1 - Anonimo 2
AM - Armenia 2
CI - Costa d'Avorio 2
HN - Honduras 2
HR - Croazia 2
KH - Cambogia 2
NZ - Nuova Zelanda 2
OM - Oman 2
PS - Palestinian Territory 2
SR - Suriname 2
SY - Repubblica araba siriana 2
AO - Angola 1
BB - Barbados 1
BG - Bulgaria 1
BJ - Benin 1
BN - Brunei Darussalam 1
BW - Botswana 1
Totale 262.281
Città #
Cagliari 237.467
Uta 5.175
Ashburn 979
Singapore 956
Fairfield 825
Woodbridge 764
San Jose 634
Dallas 546
Chandler 541
Boardman 443
Houston 427
Nyköping 418
Seattle 369
Wilmington 363
Ann Arbor 352
Beijing 338
Cambridge 306
Jacksonville 290
New York 280
Council Bluffs 249
Los Angeles 211
Dearborn 198
Helsinki 184
Santa Clara 178
Shanghai 131
The Dalles 128
Hong Kong 126
Lauterbourg 124
Nanjing 119
Boston 109
Ho Chi Minh City 109
Hefei 104
Seoul 81
Hanoi 76
Dong Ket 69
Buffalo 65
Redwood City 64
Rome 62
Munich 55
Columbus 52
San Diego 50
Milan 49
Redondo Beach 41
Tokyo 41
Guangzhou 40
Herndon 40
São Paulo 40
Casablanca 39
Atlanta 36
Nanchang 36
Chicago 35
Changsha 32
Warsaw 32
Amsterdam 31
Mountain View 31
Shenyang 31
Tianjin 31
London 29
Orem 28
Phoenix 28
Toronto 28
Montreal 26
Rio de Janeiro 25
Vienna 25
Frankfurt am Main 24
Hebei 24
Baghdad 21
Jiaxing 21
Chennai 20
Orange 20
Brooklyn 19
Istanbul 19
Tashkent 19
Washington 19
Hangzhou 18
Johannesburg 18
Norwalk 18
Ottawa 18
Guayaquil 17
Shenzhen 17
Da Nang 16
Mumbai 16
Sassari 16
Turku 16
Jinan 15
Lappeenranta 15
Nuremberg 15
Pune 15
San Francisco 15
Verona 15
Wuhan 15
Denver 14
Stockholm 14
Brussels 13
Kunming 13
Lahore 13
Naples 13
Zhengzhou 13
Contagem 11
Dhaka 11
Totale 255.387
Nome #
(3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro- 1H -indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase 14.733
Design, synthesis, and biological evaluation of 1,3-diarylpropenones as dual inhibitors of HIV-1 reverse transcriptase 4.541
Biological activities of aerial parts extracts of Euphorbia characias 4.449
Ribonuclease H/DNA polymerase HIV-1 reverse transcriptase dual inhibitor: mechanistic studies on the allosteric mode of action of isatin-based compound RMNC6 4.336
Identification of Myricetin as Ebolavirus VP35-dsRNA interaction inhibitor through a novel fluorescence-based assay 3.761
Euphorbia characias latex: Micromorphology of rubber particles and rubber transferase activity 3.682
Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 Reverse transcriptase-associated RNase H and RDDP functions 3.520
Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach 3.496
Dual HIV-1 reverse transcriptase and integrase inhibitors from Limonium morisianum Arrigoni, an endemic species of Sardinia (Italy) 3.455
Sennoside A, derived from the traditional chinese medicine plant Rheum L., is a new dual HIV-1 inhibitor effective on HIV-1 replication 3.446
Design and synthesis of new isatin derivatives as HIV-1 reverse transcriptase associated ribonuclease H inhibitors 3.363
Studies on Cycloheptathiophene-3-carboxamide Derivatives as Allosteric HIV-1 Ribonuclease H Inhibitors 3.318
Multi-target activity of Hemidesmus indicus decoction against innovative HIV-1 drug targets and characterization of Lupeol mode of action 3.304
New insights into the operative network of FaEO, an enone oxidoreductase from Fragaria x ananassa Duch 3.118
S-layer proteins as a source of carotenoids: Isolation of the carotenoid cofactor deinoxanthin from its S-layer protein DR_2577 3.096
Inhibition of HIV-1 reverse transcriptase dimerization by small molecules 3.090
Prenylated phloroglucinols from Hypericum scruglii, an endemic species of Sardinia (Italy), as new dual HIV-1 inhibitors effective on HIV-1 replication 3.059
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Dual Inhibitors of HIV-1 RT. 3.048
Onopordum illyricum L., a Mediterranean plant, as a source of anti HIV-1 compounds 3.007
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) enlighten the mechanism of action of a new Ribonuclease H/DNA polymerase RT dual inhibitor 2.987
Purification and characterization of DR_2577 (SlpA) a major S-layer protein from Deinococcus radiodurans 2.974
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Single Site Dual Inhibitors of HIV-1 RT 2.939
Preliminary study of endemic plants of Sardinia as a source of new antiviral agents 2.939
From the traditional Chinese medicine plant Schisandra chinensis new scaffolds effective on HIV-1 reverse transcriptase resistant to non-nucleoside inhibitors 2.932
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) shed light on the mechanism of action of a new Ribonuclease H/ DNA polymerase RT dual inhibitor 2.931
Structure-guided approach identifies a novel class of HIV-1 Ribonuclease H inhibitors: Binding mode insights through magnesium complexation and site-directed mutagenesis studies 2.891
Chelation motifs affecting metal-dependent viral enzymes: N′-acylhydrazone ligands as dual target inhibitors of HIV-1 Integrase and Reverse Transcriptase Ribonuclease H domain 2.880
Hypericum hircinum L. components as new single-molecule inhibitors of both HIV-1 reverse transcriptase-associated DNA polymerase and ribonuclease H activities 2.879
On the S-layer of Thermus thermophilus and the assembling of its main protein SIpA 2.855
Natural Product Kuwanon-L Inhibits HIV-1 Replication through Multiple Target Binding 2.832
RhVI1 is a membrane-anchored vacuolar invertase highly expressed in Rosa hybrida L. petals 2.821
Mutagenic study on HIV-1 reverse transcriptase to explore the mechanism of action of HIV-1 reverse transcriptase dual inhibitors 2.779
Chromenone derivatives as a versatile scaffold with dual mode of inhibition of HIV-1 reverse transcriptase-associated Ribonuclease H function and integrase activity 2.737
null 2.719
New insights into the interaction between pyrrolyl diketoacids and HIV-1 integrase active site and comparison with RNase H 2.715
3-[2-(4-aryl-1,3-thiazol-2-yl)hydrazin-1-ylidene]-1H-indol-2-ones as new potential dual inhibitors of polimerase and ribonuclease HIV-1 RT associated function 2.624
Identification of a novel HERV-K(HML10): comprehensive characterization and comparative analysis in non-human primates provide insights about HML10 proviruses structure and diffusion 2.584
Chalcones as novel dual inhibitors of HIV-1 reverse transcriptase 2.469
Structure-Activity Relationship of Pyrrolyl Diketo Acid Derivatives as Dual Inhibitors of HIV-1 Integrase and Reverse Transcriptase Ribonuclease H Domain 2.435
Inhibition of HIV-1 reverse transcriptase associated activities by the hydroalcoholic extract of Casimiroa edulis seeds 2.428
Validation of a computed radiography device to monitor the HIV-1 RNase H activity 2.411
An efficient route to novel uracil-based drug-like molecules 2.375
Inhibitory effect of 2,3,5,6-tetrafluoro-4-[4-(Aryl)-1H-1,2,3-triazol-1-yl]benzenesulfonamide derivatives on HIV reverse transcriptase associated rnase H activities 2.372
Improvement of the activity of the anti-HIV-1 integrase aptamer T30175 by introducing a modified thymidine into the loops 2.355
A Luciferase Reporter Gene Assay to Measure Ebola Virus Viral Protein 35–Associated Inhibition of Double-Stranded RNA–Stimulated, Retinoic Acid–Inducible Gene 1–Mediated Induction of Interferon β 2.320
Exploring new scaffolds for the inibition of the Ribonuclease H function of RT HIV-1 2.280
2-(Arylamino)-6-(trifluoromethyl)nicotinic Acid Derivatives: New HIV-1 RT Dual Inhibitors Active on Viral Replication 2.266
Development and identification of a novel anti-HIV-1 peptide derived by modification of the N-terminal domain of HIV-1 integrase 2.225
Investigation on the sucrose binding pocket of HIV-1 Integrase by molecular dynamics and synergy experiments 2.222
Design and synthesis of new Isatin derivatives as HIV-1 Reverse Transcriptase associated Ribonuclease H inhibitors twenty-fourth 2.164
Isatin derivatives as new scaffolds for HIV-1 reverse transcriptase associated RNase H and RDDP dual inhibitors 2.155
Discovery of dihydroxyindole-2-carboxylic acid derivatives as dual allosteric HIV-1 Integrase and Reverse Transcriptase associated Ribonuclease H inhibitors 2.141
Targeting HIV-1 RNase H: N'-(2-Hydroxy-benzylidene)-3,4,5-Trihydroxybenzoylhydrazone as Selective Inhibitor Active against NNRTIs-Resistant Variants 2.117
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases 2.115
Design, synthesis and biolgical activity evaluation of new HIV-1 reverse transcriptase dual inhibitors 2.097
Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach 2.090
Kuwanon-L as a new allosteric HIV-1 integrase inhibitor: molecular modeling and biological evaluation 2.080
6-(1-Benzyl-1H-pyrrol-2-yl)-2,4-dioxo-5-hexenoic acids as dual inhibitors of recombinant HIV-1 integrase and ribonuclease H, synthesized by a parallel synthesis approach 2.046
Design, synthesis and biological activity evaluation of new HIV-1 reverse transcriptase dual inhibitors 1.984
DHFR Inhibitors Display a Pleiotropic Anti-Viral Activity against SARS-CoV-2: Insights into the Mechanisms of Action 1.898
Design of new inhibitors of the HIV-1 Reverse Transcriptase associated Ribonuclease H function: a synthetic approach 1.893
Pyrrolyl Pyrazoles as Non-Diketo Acid Inhibitors of the HIV-1 Ribonuclease H Function of Reverse Transcriptase 1.887
null 1.851
Scaffold hopping and optimisation of 3’,4’-dihydroxyphenyl- containing thienopyrimidinones: synthesis of quinazolinone derivatives as novel allosteric inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H 1.839
Identification of new scaffolds for the inhibition of HIV-1 Reverse Transcriptase associated Ribonuclease H function by means of shape based similarity screening 1.822
null 1.820
SITE DIRECT MUTAGENESIS AND KINETIC STUDIES TO EXPLORE THE MECHANISM OF ACTION OF ISATIN DERIVATIVES AS HIV-1 REVERSE TRANSCRIPTASE DUAL INHIBITORS 1.810
The traditional Chinese medicine plant Schisandra Chinensis as source of new HIV-1 reverse transcriptase inhibitor scaffolds effective also on non-nucleoside resistant reverse transcriptases 1.809
Inhibition of HIV-1 Ribonuclease H activity by novel frangula-emodine derivatives 1.767
HIV-1 inhibiting activity of the essential oil of Ridolfia segetum and Oenanthe crocata 1.761
New anthraquinone derivatives as inhibitors of the HIV-1 reverse transcriptase-associated ribonuclease H function 1.727
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and Ribonuclease H activities effective also on non-nucleoside resistant RTs 1.722
Exploring new scaffolds for the inhibition of the Ribonuclease H function of RT HIV-1 1.715
dsRNA binding characterization of full length recombinant wild type and mutants Zaire ebolavirus VP35 1.712
Synthesis and biological evaluation of new dual inhibitors of HIV-1 associated functions 1.618
Effects of new quinizarin derivatives on both HCV NS5B RNA polymerase and HIV-1 reverse transcriptase associated ribonuclease H activities 1.613
Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen 1.586
From classic to innovative approaches in HIV-1 infection treatment 1.571
Development of a Raltegravir-based Photoaffinity-Labeled Probe for Human Immunodeficiency Virus-1 Integrase Capture 1.561
Anti-HIV-1 activity of compounds isolated from Hypericum hircinum. 1.550
Identification of highly conserved residues involved in inhibition of HIV-1 RNase H function by Diketo acid derivatives 1.546
Probing the importance of the g-quadruplex grooves for the activity of the anti-hiv-integrase aptamer t30923 1.483
A Homogeneous Time Resolved Fluorescence (HTRF) method for the evaluation of HIV-1 integrase dimerization, enzyme reactions and interaction with LEDGF/p75 1.470
Can the ever-promising target HIV reverse transcriptase-associated RNase H become a success story for drug development? 1.442
Shape based computer aided similarity screening: a valid tool in the discovery of new scaffolds for the inhibition of HIV-1 reverse transcriptase associated ribonuclease H function 1.439
Effect of Non-nucleoside Reverse Transcriptase Inhibitors on the HIV-1 Reverse Transcriptase Associated Ribonuclease-H Activity 1.396
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase (RT) -associated DNA polymerase and Ribonuclease H (RNase H) activities effective also on the RNase H activity of non-nucleoside resistant RTs 1.389
Natural Compounds Inhibit SARS-CoV-2 nsp13 Unwinding and ATPase Enzyme Activities 1.314
Cytopathic SARS-CoV-2 screening on VERO-E6 cells in a large-scale repurposing effort 1.233
null 1.214
Exploring new scaffolds for the dual inhibition of HIV-1 RT polymerase and ribonuclease associated functions 1.212
A combined shape-, 2D-fingerprint-and pharmacophore-based virtual screening for the identification of dual inhibitors targeting HIV-1 reverse transcriptase. 1.189
HIV-1 reverse transcriptase and K562 cell replication inhibition by Ridolfia segetum (L.) Moris essential oil 1.165
A combined cell based and site directed mutagenesis approach defines highly conserved residues involved in the selective inhibition of the HIV-1 ribonuclease H function by diketoacid derivatives 1.148
In Vitro Anti-HIV-1 Reverse Transcriptase and Integrase Properties of Punica granatum L. Leaves, Bark, and Peel Extracts and Their Main Compounds 1.129
Strigolactones as broad-spectrum antivirals against β-coronaviruses through targeting the main protease Mpro 1.097
Purification and functional characterization of the full length recombinant Ebola virus VP35 protein expressed in E. coli 1.073
Past and future. Current drugs targeting HIV-1 integrase and reverse transcriptase-associated ribonuclease H activity: single and dual active site inhibitors 1.057
Quinolinonyl Non-Diketo Acid Derivatives as Inhibitors of HIV-1 Ribonuclease H and Polymerase Functions of Reverse Transcriptase 999
Chemical Characterization and Anti-HIV-1 Activity Assessment of Iridoids and Flavonols from Scrophularia trifoliata 988
Totale 239.502
Categoria #
all - tutte 319.848
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 319.848


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/202212.078 0 1.020 642 772 1.064 1.094 720 579 1.260 1.273 1.812 1.842
2022/202321.107 1.698 2.901 2.540 2.044 1.399 2.491 1.086 1.683 1.162 1.243 1.870 990
2023/202420.613 905 749 1.251 1.736 2.153 3.614 2.934 1.418 986 1.195 1.758 1.914
2024/202544.636 10.914 13.148 6.932 4.236 1.988 2.388 3.362 145 411 305 323 484
2025/202610.856 704 353 1.285 918 938 730 1.638 983 736 1.356 750 465
2026/2027619 266 353 0 0 0 0 0 0 0 0 0 0
Totale 262.857