UNICA IRIS Institutional Research Information System

ESPOSITO, FRANCESCA
 Distribuzione geografica
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Continente #
EU - Europa 195.079
NA - Nord America 6.617
AS - Asia 774
AF - Africa 17
Continente sconosciuto - Info sul continente non disponibili 10
OC - Oceania 5
SA - Sud America 4
Totale 202.506
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Nazione #
IT - Italia 193.358
US - Stati Uniti d'America 6.568
UA - Ucraina 581
CN - Cina 548
SE - Svezia 543
DE - Germania 220
FI - Finlandia 149
GB - Regno Unito 118
VN - Vietnam 71
CA - Canada 44
FR - Francia 42
IN - India 41
SG - Singapore 36
HK - Hong Kong 15
BE - Belgio 11
PK - Pakistan 11
PL - Polonia 11
IR - Iran 10
TR - Turchia 9
EU - Europa 8
ES - Italia 7
JP - Giappone 7
NL - Olanda 7
IQ - Iraq 6
ID - Indonesia 5
RU - Federazione Russa 5
ZA - Sudafrica 5
AU - Australia 4
LV - Lettonia 4
NO - Norvegia 4
TW - Taiwan 4
CL - Cile 3
CZ - Repubblica Ceca 3
DZ - Algeria 3
EG - Egitto 3
IE - Irlanda 3
KR - Corea 3
MX - Messico 3
TN - Tunisia 3
A1 - Anonimo 2
AT - Austria 2
CH - Svizzera 2
HR - Croazia 2
IL - Israele 2
MU - Mauritius 2
PT - Portogallo 2
SA - Arabia Saudita 2
TH - Thailandia 2
AE - Emirati Arabi Uniti 1
BR - Brasile 1
CR - Costa Rica 1
DO - Repubblica Dominicana 1
GR - Grecia 1
HU - Ungheria 1
LU - Lussemburgo 1
MA - Marocco 1
NZ - Nuova Zelanda 1
RO - Romania 1
SI - Slovenia 1
TJ - Tagikistan 1
Totale 202.506
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Città #
Cagliari 192.817
Fairfield 825
Woodbridge 764
Chandler 541
Ashburn 449
Nyköping 418
Houston 416
Seattle 360
Wilmington 359
Ann Arbor 352
Cambridge 304
Jacksonville 286
New York 217
Dearborn 198
Boardman 124
Nanjing 117
Boston 91
Shanghai 84
Beijing 81
Dong Ket 69
Redwood City 64
Helsinki 62
San Diego 48
Herndon 40
Nanchang 33
Mountain View 31
Shenyang 28
Milan 27
Rome 27
Changsha 24
Hebei 24
Guangzhou 23
Los Angeles 23
Toronto 22
Orange 19
Atlanta 17
Jiaxing 17
Ottawa 17
Norwalk 16
Tianjin 16
Washington 15
Verona 14
Jinan 13
London 13
Pune 13
Hong Kong 12
Sassari 12
Brussels 11
Hangzhou 11
Kunming 11
Phoenix 11
Falls Church 9
Napoli 9
Auburn Hills 8
Paris 8
Warsaw 8
Zhengzhou 8
Hefei 7
Redmond 7
Gujranwala 6
Menlo Park 6
Millbury 6
Mumbai 6
Ningbo 6
Siracusa 6
Chicago 5
Indiana 5
Istanbul 5
Kilburn 5
Quartu Sant'Elena 5
Antea 4
Bari 4
Carbonia 4
Chiswick 4
Cosenza 4
Hyderabad 4
Jakarta 4
Nanning 4
Oslo 4
Padova 4
Quartu Sant'elena 4
Rockville 4
Serramanna 4
Tappahannock 4
Trieste 4
Villanovafranca 4
Wuhan 4
Acton 3
Bad Bellingen 3
Bultei 3
Chengdu 3
Edinburgh 3
Frankfurt am Main 3
Greensboro 3
Islamabad 3
Krefeld 3
Nürnberg 3
Olbia 3
Selargius 3
Shenzhen 3
Totale 199.818
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Nome #
(3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro- 1H -indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase 4.127
Design, synthesis, and biological evaluation of 1,3-diarylpropenones as dual inhibitors of HIV-1 reverse transcriptase 4.075
Ribonuclease H/DNA polymerase HIV-1 reverse transcriptase dual inhibitor: mechanistic studies on the allosteric mode of action of isatin-based compound RMNC6 3.962
Biological activities of aerial parts extracts of Euphorbia characias 3.913
Euphorbia characias latex: Micromorphology of rubber particles and rubber transferase activity 3.371
Identification of Myricetin as Ebolavirus VP35-dsRNA interaction inhibitor through a novel fluorescence-based assay 3.212
Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach 3.116
Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 Reverse transcriptase-associated RNase H and RDDP functions 3.110
Sennoside A, derived from the traditional chinese medicine plant Rheum L., is a new dual HIV-1 inhibitor effective on HIV-1 replication 3.048
Dual HIV-1 reverse transcriptase and integrase inhibitors from Limonium morisianum Arrigoni, an endemic species of Sardinia (Italy) 2.975
Design and synthesis of new isatin derivatives as HIV-1 reverse transcriptase associated ribonuclease H inhibitors 2.950
Multi-target activity of Hemidesmus indicus decoction against innovative HIV-1 drug targets and characterization of Lupeol mode of action 2.919
Studies on Cycloheptathiophene-3-carboxamide Derivatives as Allosteric HIV-1 Ribonuclease H Inhibitors 2.908
New insights into the operative network of FaEO, an enone oxidoreductase from Fragaria x ananassa Duch 2.747
null 2.719
Prenylated phloroglucinols from Hypericum scruglii, an endemic species of Sardinia (Italy), as new dual HIV-1 inhibitors effective on HIV-1 replication 2.706
Purification and characterization of DR_2577 (SlpA) a major S-layer protein from Deinococcus radiodurans 2.667
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) shed light on the mechanism of action of a new Ribonuclease H/ DNA polymerase RT dual inhibitor 2.659
Inhibition of HIV-1 reverse transcriptase dimerization by small molecules 2.656
Onopordum illyricum L., a Mediterranean plant, as a source of anti HIV-1 compounds 2.636
Preliminary study of endemic plants of Sardinia as a source of new antiviral agents 2.631
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Single Site Dual Inhibitors of HIV-1 RT 2.618
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) enlighten the mechanism of action of a new Ribonuclease H/DNA polymerase RT dual inhibitor 2.618
Chelation motifs affecting metal-dependent viral enzymes: N′-acylhydrazone ligands as dual target inhibitors of HIV-1 Integrase and Reverse Transcriptase Ribonuclease H domain 2.556
From the traditional Chinese medicine plant Schisandra chinensis new scaffolds effective on HIV-1 reverse transcriptase resistant to non-nucleoside inhibitors 2.551
Hypericum hircinum L. components as new single-molecule inhibitors of both HIV-1 reverse transcriptase-associated DNA polymerase and ribonuclease H activities 2.542
S-layer proteins as a source of carotenoids: Isolation of the carotenoid cofactor deinoxanthin from its S-layer protein DR_2577 2.536
RhVI1 is a membrane-anchored vacuolar invertase highly expressed in Rosa hybrida L. petals 2.462
On the S-layer of Thermus thermophilus and the assembling of its main protein SIpA 2.436
Natural Product Kuwanon-L Inhibits HIV-1 Replication through Multiple Target Binding 2.422
Chromenone derivatives as a versatile scaffold with dual mode of inhibition of HIV-1 reverse transcriptase-associated Ribonuclease H function and integrase activity 2.408
New insights into the interaction between pyrrolyl diketoacids and HIV-1 integrase active site and comparison with RNase H 2.394
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Dual Inhibitors of HIV-1 RT. 2.328
Structure-guided approach identifies a novel class of HIV-1 Ribonuclease H inhibitors: Binding mode insights through magnesium complexation and site-directed mutagenesis studies 2.263
Identification of a novel HERV-K(HML10): comprehensive characterization and comparative analysis in non-human primates provide insights about HML10 proviruses structure and diffusion 2.222
Chalcones as novel dual inhibitors of HIV-1 reverse transcriptase 2.204
An efficient route to novel uracil-based drug-like molecules 2.172
Structure-Activity Relationship of Pyrrolyl Diketo Acid Derivatives as Dual Inhibitors of HIV-1 Integrase and Reverse Transcriptase Ribonuclease H Domain 2.124
3-[2-(4-aryl-1,3-thiazol-2-yl)hydrazin-1-ylidene]-1H-indol-2-ones as new potential dual inhibitors of polimerase and ribonuclease HIV-1 RT associated function 2.103
Validation of a computed radiography device to monitor the HIV-1 RNase H activity 2.099
A Luciferase Reporter Gene Assay to Measure Ebola Virus Viral Protein 35–Associated Inhibition of Double-Stranded RNA–Stimulated, Retinoic Acid–Inducible Gene 1–Mediated Induction of Interferon β 2.064
Exploring new scaffolds for the inibition of the Ribonuclease H function of RT HIV-1 2.021
Investigation on the sucrose binding pocket of HIV-1 Integrase by molecular dynamics and synergy experiments 2.020
Improvement of the activity of the anti-HIV-1 integrase aptamer T30175 by introducing a modified thymidine into the loops 2.004
Development and identification of a novel anti-HIV-1 peptide derived by modification of the N-terminal domain of HIV-1 integrase 1.953
Design and synthesis of new Isatin derivatives as HIV-1 Reverse Transcriptase associated Ribonuclease H inhibitors twenty-fourth 1.922
Inhibitory effect of 2,3,5,6-tetrafluoro-4-[4-(Aryl)-1H-1,2,3-triazol-1-yl]benzenesulfonamide derivatives on HIV reverse transcriptase associated rnase H activities 1.914
Inhibition of HIV-1 reverse transcriptase associated activities by the hydroalcoholic extract of Casimiroa edulis seeds 1.890
null 1.851
Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach 1.833
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases 1.830
2-(Arylamino)-6-(trifluoromethyl)nicotinic Acid Derivatives: New HIV-1 RT Dual Inhibitors Active on Viral Replication 1.823
Kuwanon-L as a new allosteric HIV-1 integrase inhibitor: molecular modeling and biological evaluation 1.821
null 1.820
Mutagenic study on HIV-1 reverse transcriptase to explore the mechanism of action of HIV-1 reverse transcriptase dual inhibitors 1.778
6-(1-Benzyl-1H-pyrrol-2-yl)-2,4-dioxo-5-hexenoic acids as dual inhibitors of recombinant HIV-1 integrase and ribonuclease H, synthesized by a parallel synthesis approach 1.766
Discovery of dihydroxyindole-2-carboxylic acid derivatives as dual allosteric HIV-1 Integrase and Reverse Transcriptase associated Ribonuclease H inhibitors 1.765
Targeting HIV-1 RNase H: N'-(2-Hydroxy-benzylidene)-3,4,5-Trihydroxybenzoylhydrazone as Selective Inhibitor Active against NNRTIs-Resistant Variants 1.738
Isatin derivatives as new scaffolds for HIV-1 reverse transcriptase associated RNase H and RDDP dual inhibitors 1.715
Design of new inhibitors of the HIV-1 Reverse Transcriptase associated Ribonuclease H function: a synthetic approach 1.694
Design, synthesis and biolgical activity evaluation of new HIV-1 reverse transcriptase dual inhibitors 1.629
Pyrrolyl Pyrazoles as Non-Diketo Acid Inhibitors of the HIV-1 Ribonuclease H Function of Reverse Transcriptase 1.556
HIV-1 inhibiting activity of the essential oil of Ridolfia segetum and Oenanthe crocata 1.537
Inhibition of HIV-1 Ribonuclease H activity by novel frangula-emodine derivatives 1.527
Identification of new scaffolds for the inhibition of HIV-1 Reverse Transcriptase associated Ribonuclease H function by means of shape based similarity screening 1.514
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and Ribonuclease H activities effective also on non-nucleoside resistant RTs 1.493
New anthraquinone derivatives as inhibitors of the HIV-1 reverse transcriptase-associated ribonuclease H function 1.474
SITE DIRECT MUTAGENESIS AND KINETIC STUDIES TO EXPLORE THE MECHANISM OF ACTION OF ISATIN DERIVATIVES AS HIV-1 REVERSE TRANSCRIPTASE DUAL INHIBITORS 1.464
dsRNA binding characterization of full length recombinant wild type and mutants Zaire ebolavirus VP35 1.463
The traditional Chinese medicine plant Schisandra Chinensis as source of new HIV-1 reverse transcriptase inhibitor scaffolds effective also on non-nucleoside resistant reverse transcriptases 1.445
Exploring new scaffolds for the inhibition of the Ribonuclease H function of RT HIV-1 1.416
Effects of new quinizarin derivatives on both HCV NS5B RNA polymerase and HIV-1 reverse transcriptase associated ribonuclease H activities 1.396
Design, synthesis and biological activity evaluation of new HIV-1 reverse transcriptase dual inhibitors 1.391
Scaffold hopping and optimisation of 3’,4’-dihydroxyphenyl- containing thienopyrimidinones: synthesis of quinazolinone derivatives as novel allosteric inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H 1.378
From classic to innovative approaches in HIV-1 infection treatment 1.304
Identification of highly conserved residues involved in inhibition of HIV-1 RNase H function by Diketo acid derivatives 1.301
Synthesis and biological evaluation of new dual inhibitors of HIV-1 associated functions 1.297
Anti-HIV-1 activity of compounds isolated from Hypericum hircinum. 1.288
Can the ever-promising target HIV reverse transcriptase-associated RNase H become a success story for drug development? 1.258
A Homogeneous Time Resolved Fluorescence (HTRF) method for the evaluation of HIV-1 integrase dimerization, enzyme reactions and interaction with LEDGF/p75 1.244
Effect of Non-nucleoside Reverse Transcriptase Inhibitors on the HIV-1 Reverse Transcriptase Associated Ribonuclease-H Activity 1.237
Development of a Raltegravir-based Photoaffinity-Labeled Probe for Human Immunodeficiency Virus-1 Integrase Capture 1.220
null 1.214
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase (RT) -associated DNA polymerase and Ribonuclease H (RNase H) activities effective also on the RNase H activity of non-nucleoside resistant RTs 1.143
Shape based computer aided similarity screening: a valid tool in the discovery of new scaffolds for the inhibition of HIV-1 reverse transcriptase associated ribonuclease H function 1.134
Probing the importance of the g-quadruplex grooves for the activity of the anti-hiv-integrase aptamer t30923 1.073
Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen 1.051
HIV-1 reverse transcriptase and K562 cell replication inhibition by Ridolfia segetum (L.) Moris essential oil 993
A combined shape-, 2D-fingerprint-and pharmacophore-based virtual screening for the identification of dual inhibitors targeting HIV-1 reverse transcriptase. 905
Past and future. Current drugs targeting HIV-1 integrase and reverse transcriptase-associated ribonuclease H activity: single and dual active site inhibitors 825
Development of 3-hydroxyquinolein-2(1H)-ones as inhibitors of HIV-1 integrase and ribonuclease H function of reverse transcriptase 819
A combined cell based and site directed mutagenesis approach defines highly conserved residues involved in the selective inhibition of the HIV-1 ribonuclease H function by diketoacid derivatives 778
Exploring new scaffolds for the dual inhibition of HIV-1 RT polymerase and ribonuclease associated functions 741
Development of a series of 3-hydroxyquinolin-2(1H)-ones as selective inhibitors of HIV-1 reverse transcriptase associated RNase H activity 694
In Vitro Anti-HIV-1 Reverse Transcriptase and Integrase Properties of Punica granatum L. Leaves, Bark, and Peel Extracts and Their Main Compounds 657
Hemidesmus Indicus: Dall’antica Tradizone Ayurvedica Alle Potenzilità Anti-HIV1 E Nei Disordini Multifattoriali 649
HIV-1 Reverse Transcriptase still remains a new drug target: Structure, Function, Classical inhibitors and new inhibitors with innovative mechanism of action 640
Development of a series of 3-hydroxyquinolein-2(1H)-ones as selective inhibitors of HIV-1 reverse transcriptase associated RNase H activity 623
Natural Compounds Inhibit SARS-CoV-2 nsp13 Unwinding and ATPase Enzyme Activities 616
Quinolinonyl Non-Diketo Acid Derivatives as Inhibitors of HIV-1 Ribonuclease H and Polymerase Functions of Reverse Transcriptase 593
Totale 193.367
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Categoria #
all - tutte 231.075
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 231.075
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/20192.035 0 0 0 0 0 0 0 0 0 511 968 556
2019/202037.050 1.882 1.587 302 587 12.748 9.736 5.182 977 652 1.028 791 1.578
2020/202154.305 1.646 1.809 2.383 14.910 10.176 5.582 4.220 3.507 1.363 3.344 3.907 1.458
2021/202213.416 1.338 1.020 642 772 1.064 1.094 720 579 1.260 1.273 1.812 1.842
2022/202321.107 1.698 2.901 2.540 2.044 1.399 2.491 1.086 1.683 1.162 1.243 1.870 990
2023/202416.838 905 749 1.251 1.736 2.153 3.614 2.934 1.418 986 1.092 0 0
Totale 202.971