UNICA IRIS Institutional Research Information System

DISTINTO, SIMONA
 Distribuzione geografica
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Continente #
EU - Europa 267.206
NA - Nord America 7.235
AS - Asia 1.208
SA - Sud America 13
AF - Africa 11
Continente sconosciuto - Info sul continente non disponibili 8
OC - Oceania 3
Totale 275.684
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Nazione #
IT - Italia 264.943
US - Stati Uniti d'America 7.189
CN - Cina 813
UA - Ucraina 759
SE - Svezia 597
DE - Germania 322
SG - Singapore 223
FI - Finlandia 222
GB - Regno Unito 190
FR - Francia 55
VN - Vietnam 52
CA - Canada 36
IN - India 36
RU - Federazione Russa 26
HK - Hong Kong 23
PK - Pakistan 18
BE - Belgio 16
NL - Olanda 14
KR - Corea 13
AT - Austria 12
IR - Iran 11
CZ - Repubblica Ceca 10
EU - Europa 7
IE - Irlanda 7
PT - Portogallo 7
CL - Cile 6
MX - Messico 6
ES - Italia 5
EG - Egitto 4
HU - Ungheria 4
ID - Indonesia 4
PL - Polonia 4
AU - Australia 3
MA - Marocco 3
TN - Tunisia 3
TR - Turchia 3
AR - Argentina 2
CR - Costa Rica 2
HR - Croazia 2
IL - Israele 2
JP - Giappone 2
LT - Lituania 2
TW - Taiwan 2
A1 - Anonimo 1
BR - Brasile 1
CH - Svizzera 1
CM - Camerun 1
CO - Colombia 1
DO - Repubblica Dominicana 1
EC - Ecuador 1
EE - Estonia 1
IM - Isola di Man 1
IQ - Iraq 1
IS - Islanda 1
KG - Kirghizistan 1
KW - Kuwait 1
LA - Repubblica Popolare Democratica del Laos 1
LU - Lussemburgo 1
LV - Lettonia 1
PA - Panama 1
PE - Perù 1
PH - Filippine 1
RO - Romania 1
SI - Slovenia 1
SK - Slovacchia (Repubblica Slovacca) 1
TH - Thailandia 1
UY - Uruguay 1
Totale 275.684
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Città #
Cagliari 259.531
Uta 4.887
Fairfield 860
Woodbridge 665
Chandler 646
Ashburn 474
Houston 459
Nyköping 430
Boardman 402
Ann Arbor 392
Jacksonville 390
Wilmington 368
Seattle 362
Dearborn 254
Cambridge 251
Singapore 139
Nanjing 137
New York 125
Shanghai 115
Santa Clara 114
Beijing 108
Helsinki 108
Boston 103
Redwood City 54
Shenyang 52
Guangzhou 51
Dong Ket 49
Nanchang 49
San Diego 41
Hebei 33
Los Angeles 32
Changsha 31
Jiaxing 30
Mountain View 26
Milan 25
Sassari 24
Toronto 24
Herndon 23
Verona 23
London 22
Hong Kong 20
Norwalk 20
Redmond 20
Jinan 19
Tianjin 17
Brussels 16
Atlanta 15
Auburn Hills 15
Kunming 14
Orange 14
Rome 14
Hangzhou 13
Seoul 13
Amsterdam 12
Washington 12
Zhengzhou 12
Gujranwala 11
Vienna 11
Munich 10
Taizhou 10
Wuhan 10
Frankfurt am Main 9
Mumbai 9
Ottawa 9
Olbia 8
Phoenix 8
Walnut 8
Brno 7
Hefei 7
Quartu Sant'Elena 7
Quartu Sant'elena 7
Falls Church 6
Indiana 6
Millbury 6
Ningbo 6
Paris 6
Saint Petersburg 6
San Francisco 6
Cosenza 5
Dublin 5
Pune 5
Selargius 5
Siracusa 5
Yellow Springs 5
Zerfalìu 5
Berlin 4
Borås 4
Chengdu 4
Moscow 4
Wuxi 4
Bultei 3
Chiswick 3
Hanoi 3
Jakarta 3
Kilburn 3
La Jolla 3
Napoli 3
Pisa 3
Piscataway 3
Rabat 3
Totale 272.413
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Nome #
(3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro- 1H -indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase 14.622
Exploring the thiazole scaffold for the identification of new agents for the treatment of fluconazole resistant Candida 4.943
Methoxyflavones from Stachys glutinosa with binding affinity to opioid receptors: in silico, in vitro, and in vivo studies 4.605
Phenylpropenoids from Bupleurum fruticosum as Anti-Human Rhinovirus Species A Selective Capsid Binders 4.579
Natural product-inspired esters and amides of ferulic and caffeic acid as dual inhibitors of HIV-1 reverse transcriptase 4.571
Design, synthesis, and biological evaluation of 1,3-diarylpropenones as dual inhibitors of HIV-1 reverse transcriptase 4.392
Isatin: a privileged scaffold for the design of carbonic anhydrase inhibitors 4.341
Quercetin blocks Ebola Virus infection by counteracting the VP24 Interferon inhibitory function 4.308
2-(2-cycloalkylidene hydrazin-1-yl)-4-aryl-1,3-thiazoles: a promising class of antifungal agents 4.302
Ribonuclease H/DNA polymerase HIV-1 reverse transcriptase dual inhibitor: mechanistic studies on the allosteric mode of action of isatin-based compound RMNC6 4.244
3-Acetyl-2,5-diaryl-2,3-dihydro-1,3,4-oxadiazoles: A new scaffold for the selective inhibition of monoamine oxidase B 4.217
Isatin thiazoline hybrids as dual inhibitors of HIV-1 reverse transcriptase 4.075
N-Alkyl dien- and trienamides from the roots of Otanthus maritimus with binding affinity for opioid and cannabinoid receptors 3.856
New 4-[(3-cyclohexyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzene-1-sulfonamides, synthesis and inhibitory activity toward carbonic anhydrase I, II, IX, XII 3.838
Drug design, synthesis, in vitro and in silico evaluation of selective monoaminoxidase B inhibitors based on 3-acetyl-2-dichlorophenyl-5-aryl-2,3-dihydro-1,3,4-oxadiazole chemical scaffold 3.684
A novel series of 3,4-disubstituted dihydropyrazoles: Synthesis and evaluation for MAO enzyme inhibition 3.669
Identification of Myricetin as Ebolavirus VP35-dsRNA interaction inhibitor through a novel fluorescence-based assay 3.625
Ferulic Acid Esters and Withanolides: in Search of Withania somnifera GABAA Receptor Modulators 3.482
Targeting tumor associated carbonic anhydrase IX and XII: Highly isozyme selective coumarin and psoralen inhibitors 3.453
Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 Reverse transcriptase-associated RNase H and RDDP functions 3.412
Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach 3.371
Sennoside A, derived from the traditional chinese medicine plant Rheum L., is a new dual HIV-1 inhibitor effective on HIV-1 replication 3.340
N-alkylamides from Otanthus maritimus: structure elucidation, binding affinity for cannabinoid receptors and computational study 3.300
Coumarins from Magydaris pastinacea as inhibitors of the tumour-associated carbonic anhydrases IX and XII: isolation, biological studies and in silico evaluation 3.276
Through scaffold modification to 3,5-diaryl-4,5-dihydroisoxazoles: new potent and selective inhibitors of monoamine oxidase B 3.276
Molecular Aspects of the RT/drug Interactions. Perspective of Dual Inhibitors 3.231
Multi-target activity of Hemidesmus indicus decoction against innovative HIV-1 drug targets and characterization of Lupeol mode of action 3.220
Studies on Cycloheptathiophene-3-carboxamide Derivatives as Allosteric HIV-1 Ribonuclease H Inhibitors 3.203
Synthesis and biological assessment of novel 2-thiazolylhydrazones and computational analysis of their recognition by monoamine oxidase B 3.177
Synthesis of new 3-aryl-4,5-dihydropyrazole-1-carbothioamide derivatives. An investigation on their ability to inhibit monoamine oxidase 3.139
N-Acylbenzenesulfonamide dihydro-1,3,4-oxadiazole hybrids: seeking selectivity toward carbonic anhydrase isoforms 3.096
Novel natural non-nucleoside inhibitors of HIV-1 reverse transcriptase identified by shape- and structure-based virtual screening techniques 2.990
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Dual Inhibitors of HIV-1 RT. 2.960
Tuning the Dual Inhibition of Carbonic Anhydrase and Cyclooxygenase by Dihydrothiazole Benzensulfonamides 2.926
Investigating the Anticancer Activity of Isatin/Dihydropyrazole Hybrids 2.919
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) enlighten the mechanism of action of a new Ribonuclease H/DNA polymerase RT dual inhibitor 2.880
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) shed light on the mechanism of action of a new Ribonuclease H/ DNA polymerase RT dual inhibitor 2.827
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Single Site Dual Inhibitors of HIV-1 RT 2.810
From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors 2.763
Mutagenic study on HIV-1 reverse transcriptase to explore the mechanism of action of HIV-1 reverse transcriptase dual inhibitors 2.688
MD protocol validation for the study of MAOB-inhibitor complexes 2.683
In search of new antitumor agents through the combination of individually active moieties: construction of a [3,5-diaryl-(4,5- dihydropyrazol-1-yl)-4-oxo-1,3-thiazol-5-ylidene]- 1H-indol-2-ones library 2.650
Synthesis and biological activity evaluation of new dual-inhibitors of both associated functions of HIV-1 RT 2.552
3-[2-(4-aryl-1,3-thiazol-2-yl)hydrazin-1-ylidene]-1H-indol-2-ones as new potential dual inhibitors of polimerase and ribonuclease HIV-1 RT associated function 2.534
Structure-based virtual screening of novel natural alkaloid derivatives as potential binders of h-telo and c-myc DNA G-quadruplex conformations 2.533
Towards the total block of HIV-1 Reverse Transcriptase: the dual-inhibitors approach 2.527
Synthesis and characterization of new phthalhydrazothiazole derivatives: A preliminary investigation on their activity against hepatocellular carcinoma 2.444
Investigation on the mechanism of action of new dual inhibitors of HIV-1 RT 2.442
Exploring new structural features of the 4-[(3-methyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzenesulphonamide scaffold for the inhibition of human carbonic anhydrases 2.442
Chalcones as novel dual inhibitors of HIV-1 reverse transcriptase 2.361
New dual inhibitors of RT associated functions: investigation on their mechanism and mode of action 2.349
New promising scaffolds for the inhibition of monoamine oxidase B 2.224
Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement 2.208
Exploring new scaffolds for the inibition of the Ribonuclease H function of RT HIV-1 2.174
Design and synthesis of new Isatin derivatives as HIV-1 Reverse Transcriptase associated Ribonuclease H inhibitors twenty-fourth 2.080
Isatin derivatives as new scaffolds for HIV-1 reverse transcriptase associated RNase H and RDDP dual inhibitors 2.048
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases 1.988
Targeting HIV-1 RNase H: N'-(2-Hydroxy-benzylidene)-3,4,5-Trihydroxybenzoylhydrazone as Selective Inhibitor Active against NNRTIs-Resistant Variants 1.987
Design, synthesis and biological activity evaluation of c-myc proto-oncogene binders as potential antitumor agents 1.953
null 1.949
Design, synthesis and biological activity evaluation of new HIV-1 reverse transcriptase dual inhibitors 1.890
Synthesis and anti-microbial activity evaluation of some new 1-benzoyl-isothiosemicarbazides. 1.852
Design of new inhibitors of the HIV-1 Reverse Transcriptase associated Ribonuclease H function: a synthetic approach 1.807
Synthesis, semipreparative HPLC separation, biological evaluation, and 3D-QSAR of hydrazothiazole derivatives as human monoamine oxidase B inhibitors 1.796
Identification of new scaffolds for the inhibition of HIV-1 Reverse Transcriptase associated Ribonuclease H function by means of shape based similarity screening 1.724
SITE DIRECT MUTAGENESIS AND KINETIC STUDIES TO EXPLORE THE MECHANISM OF ACTION OF ISATIN DERIVATIVES AS HIV-1 REVERSE TRANSCRIPTASE DUAL INHIBITORS 1.703
Toward the design of new DNA G-quadruplex ligands through rational analysis of polymorphism and binding data 1.652
Exploring new scaffolds for the inhibition of the Ribonuclease H function of RT HIV-1 1.633
SYNTHESIS, MOLECULAR MODELLING, INHIBITORY ACTIVITY, AND SELECTIVITY TOWARDS MONOAMINE OXIDASE OF NEW HETEROCYCLIC SCAFFOLDS 1.610
New Dihydrothiazole Benzensulfonamides: Looking for Selectivity toward Carbonic Anhydrase Isoforms I, II, IX, and XII 1.605
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and Ribonuclease H activities effective also on non-nucleoside resistant RTs 1.601
Synthesis and biological evaluation of new dual inhibitors of HIV-1 associated functions 1.542
null 1.499
Flavonoids and Acid-Hydrolysis derivatives of Neo-Clerodane diterpenes from Teucrium flavum subsp. glaucum as inhibitors of the HIV-1 reverse transcriptase–associated RNase H function 1.494
From classic to innovative approaches in HIV-1 infection treatment 1.483
2-methoxynaphthalen thiazole derivate : a new HIV-1 RT Ribonuclease H/DNA polymerase dual inhibitor active on viral replication 1.421
Molecular interaction fields in drug discovery: Recent advances and future perspectives 1.340
Shape based computer aided similarity screening: a valid tool in the discovery of new scaffolds for the inhibition of HIV-1 reverse transcriptase associated ribonuclease H function 1.334
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase (RT) -associated DNA polymerase and Ribonuclease H (RNase H) activities effective also on the RNase H activity of non-nucleoside resistant RTs 1.271
Identification of G-quadruplex DNA/RNA binders: Structure-based virtual screening and biophysical characterization 1.257
9-fluorenones as new scaffolds for G-quadruplex DNA 1.158
2-(2-methyl-2-nitrovinyl)furan but not furvina interfere with staphylococcus aureus agr quorum-sensing system and potentiate the action of fusidic acid against biofilms 1.143
Cynarin blocks Ebola virus replication by counteracting VP35 inhibition of interferon-beta production 1.136
A combined shape-, 2D-fingerprint-and pharmacophore-based virtual screening for the identification of dual inhibitors targeting HIV-1 reverse transcriptase. 1.070
Synthesis, molecular modelling, inhibitory acivity, and selectivity towards monoamine oxidase of new heterocyclic scaffold 1.048
An investigation of the biological effect of structural modifications of isothiosemicarbazones and their cyclic analogues 1.041
Design, synthesis and biological evaluation of new fluorenone derivatives as DNA G-quadruplex binders 1.039
Exploring new scaffolds for the dual inhibition of HIV-1 RT polymerase and ribonuclease associated functions 1.038
GRID-based three-dimensional pharmacophores II: PharmBench, a benchmark data set for evaluating pharmacophore elucidation methods 1.031
Synthesis and in vitro activity of 2-thiazolylhydrazone derivatives compared with the activity of clotrimazole against clinical isolates of Candida spp 981
Progettazione e sintesi di 4-(5-ariliden-3-metil-4-ossotiazolidin-2-ilidenamino)benzensulfonamidi e 4-(5-alchiliden-3-metil-4-ossotiazolidin-2-ilidenammino)benzensulfonamidi quali potenziali inibitori selettivi delle ciclossigenasi 2 964
null 943
Computational approaches for discovery and optimization of monoamine oxidase B inhibitors 942
The polymorfisms of DNA G-quadruplex investigated by docking experiments with Telomestatin enantiomers 935
The polymorphisms of DNA G-quadruplex investigated by docking experiments with telomestatin enantiomers 901
1-benzenesulfonamide-1(H)-pyrazoles and 3-benzenesulfonamide-4-tiazolidinones, two promising scaffolds for the design of cycloxygenase inhibitors 877
CoMFA studies of non-covalent monoamine oxidase inhibitors 868
Tri-substituted thiazolines as promising scaffolds for the design of efficient COX inhibitors 855
The discovery of new G-quadruplex binders through a structure-based virtual screening approach 854
Combining induced fit docking and molecular dynamics simulations to predict the binding mode of new monoamine oxidase B inhibitors 848
Totale 250.924
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Categoria #
all - tutte 313.248
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 313.248
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202012.843 0 0 0 0 0 0 5.525 1.281 1.001 1.401 1.337 2.298
2020/202161.923 2.205 2.322 3.322 15.621 11.533 6.418 4.941 3.647 1.731 4.064 4.167 1.952
2021/202212.740 1.525 1.086 646 847 1.061 824 750 630 1.301 1.208 1.398 1.464
2022/202320.237 1.646 2.883 2.600 2.010 1.338 2.081 987 1.596 1.123 1.179 1.621 1.173
2023/202423.399 1.203 580 3.166 2.564 2.398 3.826 2.442 1.555 1.144 1.172 1.570 1.779
2024/202541.860 13.991 12.597 6.370 4.118 1.941 2.551 292 0 0 0 0 0
Totale 276.135