UNICA IRIS Institutional Research Information System

DISTINTO, SIMONA
 Distribuzione geografica
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Continente #
EU - Europa 270.908
NA - Nord America 9.054
AS - Asia 3.390
SA - Sud America 560
AF - Africa 137
Continente sconosciuto - Info sul continente non disponibili 8
OC - Oceania 7
Totale 284.064
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Nazione #
IT - Italia 268.292
US - Stati Uniti d'America 8.931
CN - Cina 1.526
SG - Singapore 1.225
UA - Ucraina 764
SE - Svezia 620
BR - Brasile 455
DE - Germania 412
FI - Finlandia 239
GB - Regno Unito 230
VN - Vietnam 191
FR - Francia 91
IN - India 86
KR - Corea 85
MA - Marocco 70
CA - Canada 66
HK - Hong Kong 60
AT - Austria 44
AR - Argentina 39
RU - Federazione Russa 39
NL - Olanda 38
MX - Messico 36
BD - Bangladesh 33
PL - Polonia 32
ZA - Sudafrica 29
JP - Giappone 26
PK - Pakistan 25
TR - Turchia 22
BE - Belgio 18
IE - Irlanda 16
IQ - Iraq 16
EC - Ecuador 15
ES - Italia 15
ID - Indonesia 15
CZ - Repubblica Ceca 13
IR - Iran 12
KE - Kenya 11
PY - Paraguay 11
SA - Arabia Saudita 11
VE - Venezuela 11
CL - Cile 10
EG - Egitto 10
CO - Colombia 9
JO - Giordania 9
UZ - Uzbekistan 9
PT - Portogallo 8
EU - Europa 7
LT - Lituania 7
NP - Nepal 7
PE - Perù 7
TN - Tunisia 7
PA - Panama 6
AE - Emirati Arabi Uniti 5
AU - Australia 5
CR - Costa Rica 4
HU - Ungheria 4
IL - Israele 4
KG - Kirghizistan 4
DO - Repubblica Dominicana 3
GE - Georgia 3
KW - Kuwait 3
TW - Taiwan 3
UY - Uruguay 3
AL - Albania 2
AZ - Azerbaigian 2
BA - Bosnia-Erzegovina 2
CH - Svizzera 2
DZ - Algeria 2
ET - Etiopia 2
HR - Croazia 2
IS - Islanda 2
LB - Libano 2
LV - Lettonia 2
NG - Nigeria 2
NI - Nicaragua 2
RO - Romania 2
RS - Serbia 2
SK - Slovacchia (Repubblica Slovacca) 2
A1 - Anonimo 1
BB - Barbados 1
BG - Bulgaria 1
BH - Bahrain 1
CM - Camerun 1
CU - Cuba 1
DK - Danimarca 1
EE - Estonia 1
GR - Grecia 1
GT - Guatemala 1
IM - Isola di Man 1
JM - Giamaica 1
KI - Kiribati 1
LA - Repubblica Popolare Democratica del Laos 1
LK - Sri Lanka 1
LU - Lussemburgo 1
MD - Moldavia 1
MU - Mauritius 1
MY - Malesia 1
NZ - Nuova Zelanda 1
PH - Filippine 1
SI - Slovenia 1
Totale 284.059
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Città #
Cagliari 262.708
Uta 4.995
Fairfield 860
Ashburn 777
Woodbridge 665
Chandler 646
Singapore 622
Dallas 560
Houston 462
Nyköping 430
Boardman 402
Ann Arbor 392
Jacksonville 390
Wilmington 369
Seattle 368
Beijing 326
Dearborn 254
Cambridge 251
Los Angeles 177
New York 156
Nanjing 137
Santa Clara 127
Shanghai 125
Boston 118
Helsinki 110
Hefei 102
The Dalles 95
Seoul 85
Casablanca 63
Buffalo 60
Guangzhou 54
Ho Chi Minh City 54
Redwood City 54
Hong Kong 52
Munich 52
Shenyang 52
Dong Ket 49
Nanchang 49
Chicago 44
San Diego 42
São Paulo 36
Verona 36
Milan 35
Changsha 33
Hebei 33
Redondo Beach 33
Hanoi 31
Toronto 31
Vienna 31
Jiaxing 30
Warsaw 29
Amsterdam 28
Frankfurt am Main 27
London 27
Mountain View 26
Sassari 26
Herndon 23
Tianjin 22
Phoenix 21
Tokyo 21
Norwalk 20
Redmond 20
San Francisco 20
Jinan 19
Chennai 18
Rio de Janeiro 18
Salt Lake City 18
Atlanta 16
Brussels 16
Johannesburg 16
Auburn Hills 15
Brooklyn 15
Hangzhou 15
Kunming 15
Montreal 15
Nuremberg 15
Zhengzhou 15
Dublin 14
Orange 14
Rome 14
Washington 14
Columbus 13
Council Bluffs 13
Mexico City 12
Tampa 12
Gujranwala 11
Mumbai 11
Wuhan 11
Nairobi 10
Taizhou 10
Turku 10
Amman 9
Denver 9
Düsseldorf 9
Ottawa 9
Tashkent 9
Curitiba 8
Elk Grove Village 8
Jakarta 8
Moscow 8
Totale 278.445
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Nome #
(3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro- 1H -indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase 14.690
Exploring the thiazole scaffold for the identification of new agents for the treatment of fluconazole resistant Candida 5.028
Methoxyflavones from Stachys glutinosa with binding affinity to opioid receptors: in silico, in vitro, and in vivo studies 4.677
Phenylpropenoids from Bupleurum fruticosum as Anti-Human Rhinovirus Species A Selective Capsid Binders 4.656
Natural product-inspired esters and amides of ferulic and caffeic acid as dual inhibitors of HIV-1 reverse transcriptase 4.630
Design, synthesis, and biological evaluation of 1,3-diarylpropenones as dual inhibitors of HIV-1 reverse transcriptase 4.484
Isatin: a privileged scaffold for the design of carbonic anhydrase inhibitors 4.407
Quercetin blocks Ebola Virus infection by counteracting the VP24 Interferon inhibitory function 4.401
2-(2-cycloalkylidene hydrazin-1-yl)-4-aryl-1,3-thiazoles: a promising class of antifungal agents 4.347
Ribonuclease H/DNA polymerase HIV-1 reverse transcriptase dual inhibitor: mechanistic studies on the allosteric mode of action of isatin-based compound RMNC6 4.292
3-Acetyl-2,5-diaryl-2,3-dihydro-1,3,4-oxadiazoles: A new scaffold for the selective inhibition of monoamine oxidase B 4.276
Isatin thiazoline hybrids as dual inhibitors of HIV-1 reverse transcriptase 4.146
N-Alkyl dien- and trienamides from the roots of Otanthus maritimus with binding affinity for opioid and cannabinoid receptors 3.910
New 4-[(3-cyclohexyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzene-1-sulfonamides, synthesis and inhibitory activity toward carbonic anhydrase I, II, IX, XII 3.900
Drug design, synthesis, in vitro and in silico evaluation of selective monoaminoxidase B inhibitors based on 3-acetyl-2-dichlorophenyl-5-aryl-2,3-dihydro-1,3,4-oxadiazole chemical scaffold 3.738
A novel series of 3,4-disubstituted dihydropyrazoles: Synthesis and evaluation for MAO enzyme inhibition 3.731
Identification of Myricetin as Ebolavirus VP35-dsRNA interaction inhibitor through a novel fluorescence-based assay 3.710
Ferulic Acid Esters and Withanolides: in Search of Withania somnifera GABAA Receptor Modulators 3.555
Targeting tumor associated carbonic anhydrase IX and XII: Highly isozyme selective coumarin and psoralen inhibitors 3.506
Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 Reverse transcriptase-associated RNase H and RDDP functions 3.485
Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach 3.435
Sennoside A, derived from the traditional chinese medicine plant Rheum L., is a new dual HIV-1 inhibitor effective on HIV-1 replication 3.395
Coumarins from Magydaris pastinacea as inhibitors of the tumour-associated carbonic anhydrases IX and XII: isolation, biological studies and in silico evaluation 3.378
N-alkylamides from Otanthus maritimus: structure elucidation, binding affinity for cannabinoid receptors and computational study 3.366
Through scaffold modification to 3,5-diaryl-4,5-dihydroisoxazoles: new potent and selective inhibitors of monoamine oxidase B 3.336
Molecular Aspects of the RT/drug Interactions. Perspective of Dual Inhibitors 3.280
Studies on Cycloheptathiophene-3-carboxamide Derivatives as Allosteric HIV-1 Ribonuclease H Inhibitors 3.266
Multi-target activity of Hemidesmus indicus decoction against innovative HIV-1 drug targets and characterization of Lupeol mode of action 3.262
Synthesis and biological assessment of novel 2-thiazolylhydrazones and computational analysis of their recognition by monoamine oxidase B 3.227
Synthesis of new 3-aryl-4,5-dihydropyrazole-1-carbothioamide derivatives. An investigation on their ability to inhibit monoamine oxidase 3.177
N-Acylbenzenesulfonamide dihydro-1,3,4-oxadiazole hybrids: seeking selectivity toward carbonic anhydrase isoforms 3.158
Novel natural non-nucleoside inhibitors of HIV-1 reverse transcriptase identified by shape- and structure-based virtual screening techniques 3.040
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Dual Inhibitors of HIV-1 RT. 3.004
Investigating the Anticancer Activity of Isatin/Dihydropyrazole Hybrids 2.993
Tuning the Dual Inhibition of Carbonic Anhydrase and Cyclooxygenase by Dihydrothiazole Benzensulfonamides 2.986
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) enlighten the mechanism of action of a new Ribonuclease H/DNA polymerase RT dual inhibitor 2.933
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Single Site Dual Inhibitors of HIV-1 RT 2.881
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) shed light on the mechanism of action of a new Ribonuclease H/ DNA polymerase RT dual inhibitor 2.869
From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors 2.819
Mutagenic study on HIV-1 reverse transcriptase to explore the mechanism of action of HIV-1 reverse transcriptase dual inhibitors 2.737
MD protocol validation for the study of MAOB-inhibitor complexes 2.737
In search of new antitumor agents through the combination of individually active moieties: construction of a [3,5-diaryl-(4,5- dihydropyrazol-1-yl)-4-oxo-1,3-thiazol-5-ylidene]- 1H-indol-2-ones library 2.709
Synthesis and biological activity evaluation of new dual-inhibitors of both associated functions of HIV-1 RT 2.596
Structure-based virtual screening of novel natural alkaloid derivatives as potential binders of h-telo and c-myc DNA G-quadruplex conformations 2.596
3-[2-(4-aryl-1,3-thiazol-2-yl)hydrazin-1-ylidene]-1H-indol-2-ones as new potential dual inhibitors of polimerase and ribonuclease HIV-1 RT associated function 2.579
Towards the total block of HIV-1 Reverse Transcriptase: the dual-inhibitors approach 2.571
Exploring new structural features of the 4-[(3-methyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzenesulphonamide scaffold for the inhibition of human carbonic anhydrases 2.519
Investigation on the mechanism of action of new dual inhibitors of HIV-1 RT 2.505
Synthesis and characterization of new phthalhydrazothiazole derivatives: A preliminary investigation on their activity against hepatocellular carcinoma 2.491
Chalcones as novel dual inhibitors of HIV-1 reverse transcriptase 2.418
New dual inhibitors of RT associated functions: investigation on their mechanism and mode of action 2.393
New promising scaffolds for the inhibition of monoamine oxidase B 2.270
Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement 2.257
Exploring new scaffolds for the inibition of the Ribonuclease H function of RT HIV-1 2.221
Design and synthesis of new Isatin derivatives as HIV-1 Reverse Transcriptase associated Ribonuclease H inhibitors twenty-fourth 2.124
Isatin derivatives as new scaffolds for HIV-1 reverse transcriptase associated RNase H and RDDP dual inhibitors 2.099
Targeting HIV-1 RNase H: N'-(2-Hydroxy-benzylidene)-3,4,5-Trihydroxybenzoylhydrazone as Selective Inhibitor Active against NNRTIs-Resistant Variants 2.065
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases 2.062
Design, synthesis and biological activity evaluation of c-myc proto-oncogene binders as potential antitumor agents 2.036
null 1.949
Design, synthesis and biological activity evaluation of new HIV-1 reverse transcriptase dual inhibitors 1.929
Synthesis and anti-microbial activity evaluation of some new 1-benzoyl-isothiosemicarbazides. 1.898
Design of new inhibitors of the HIV-1 Reverse Transcriptase associated Ribonuclease H function: a synthetic approach 1.849
Synthesis, semipreparative HPLC separation, biological evaluation, and 3D-QSAR of hydrazothiazole derivatives as human monoamine oxidase B inhibitors 1.838
Identification of new scaffolds for the inhibition of HIV-1 Reverse Transcriptase associated Ribonuclease H function by means of shape based similarity screening 1.769
SITE DIRECT MUTAGENESIS AND KINETIC STUDIES TO EXPLORE THE MECHANISM OF ACTION OF ISATIN DERIVATIVES AS HIV-1 REVERSE TRANSCRIPTASE DUAL INHIBITORS 1.757
Toward the design of new DNA G-quadruplex ligands through rational analysis of polymorphism and binding data 1.695
New Dihydrothiazole Benzensulfonamides: Looking for Selectivity toward Carbonic Anhydrase Isoforms I, II, IX, and XII 1.695
Exploring new scaffolds for the inhibition of the Ribonuclease H function of RT HIV-1 1.670
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and Ribonuclease H activities effective also on non-nucleoside resistant RTs 1.665
SYNTHESIS, MOLECULAR MODELLING, INHIBITORY ACTIVITY, AND SELECTIVITY TOWARDS MONOAMINE OXIDASE OF NEW HETEROCYCLIC SCAFFOLDS 1.655
Flavonoids and Acid-Hydrolysis derivatives of Neo-Clerodane diterpenes from Teucrium flavum subsp. glaucum as inhibitors of the HIV-1 reverse transcriptase–associated RNase H function 1.581
Synthesis and biological evaluation of new dual inhibitors of HIV-1 associated functions 1.579
From classic to innovative approaches in HIV-1 infection treatment 1.523
null 1.499
2-methoxynaphthalen thiazole derivate : a new HIV-1 RT Ribonuclease H/DNA polymerase dual inhibitor active on viral replication 1.473
Molecular interaction fields in drug discovery: Recent advances and future perspectives 1.385
Shape based computer aided similarity screening: a valid tool in the discovery of new scaffolds for the inhibition of HIV-1 reverse transcriptase associated ribonuclease H function 1.382
Cynarin blocks Ebola virus replication by counteracting VP35 inhibition of interferon-beta production 1.372
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase (RT) -associated DNA polymerase and Ribonuclease H (RNase H) activities effective also on the RNase H activity of non-nucleoside resistant RTs 1.332
Identification of G-quadruplex DNA/RNA binders: Structure-based virtual screening and biophysical characterization 1.298
2-(2-methyl-2-nitrovinyl)furan but not furvina interfere with staphylococcus aureus agr quorum-sensing system and potentiate the action of fusidic acid against biofilms 1.263
9-fluorenones as new scaffolds for G-quadruplex DNA 1.197
Exploring new scaffolds for the dual inhibition of HIV-1 RT polymerase and ribonuclease associated functions 1.141
A combined shape-, 2D-fingerprint-and pharmacophore-based virtual screening for the identification of dual inhibitors targeting HIV-1 reverse transcriptase. 1.130
An investigation of the biological effect of structural modifications of isothiosemicarbazones and their cyclic analogues 1.089
Synthesis, molecular modelling, inhibitory acivity, and selectivity towards monoamine oxidase of new heterocyclic scaffold 1.082
Design, synthesis and biological evaluation of new fluorenone derivatives as DNA G-quadruplex binders 1.082
GRID-based three-dimensional pharmacophores II: PharmBench, a benchmark data set for evaluating pharmacophore elucidation methods 1.071
Synthesis and in vitro activity of 2-thiazolylhydrazone derivatives compared with the activity of clotrimazole against clinical isolates of Candida spp 1.034
Progettazione e sintesi di 4-(5-ariliden-3-metil-4-ossotiazolidin-2-ilidenamino)benzensulfonamidi e 4-(5-alchiliden-3-metil-4-ossotiazolidin-2-ilidenammino)benzensulfonamidi quali potenziali inibitori selettivi delle ciclossigenasi 2 1.010
The polymorfisms of DNA G-quadruplex investigated by docking experiments with Telomestatin enantiomers 999
Computational approaches for discovery and optimization of monoamine oxidase B inhibitors 991
The polymorphisms of DNA G-quadruplex investigated by docking experiments with telomestatin enantiomers 945
null 943
1-benzenesulfonamide-1(H)-pyrazoles and 3-benzenesulfonamide-4-tiazolidinones, two promising scaffolds for the design of cycloxygenase inhibitors 933
CoMFA studies of non-covalent monoamine oxidase inhibitors 911
Tri-substituted thiazolines as promising scaffolds for the design of efficient COX inhibitors 898
The discovery of new G-quadruplex binders through a structure-based virtual screening approach 896
Combining induced fit docking and molecular dynamics simulations to predict the binding mode of new monoamine oxidase B inhibitors 882
Totale 256.649
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Categoria #
all - tutte 332.920
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 332.920
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202126.920 0 0 0 0 0 6.418 4.941 3.647 1.731 4.064 4.167 1.952
2021/202212.740 1.525 1.086 646 847 1.061 824 750 630 1.301 1.208 1.398 1.464
2022/202320.237 1.646 2.883 2.600 2.010 1.338 2.081 987 1.596 1.123 1.179 1.621 1.173
2023/202423.399 1.203 580 3.166 2.564 2.398 3.826 2.442 1.555 1.144 1.172 1.570 1.779
2024/202545.702 13.991 12.597 6.370 4.118 1.941 2.531 2.289 212 484 330 378 461
2025/20264.567 716 434 1.240 955 822 400 0 0 0 0 0 0
Totale 284.544