UNICA IRIS Institutional Research Information System

DISTINTO, SIMONA
 Distribuzione geografica
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Continente #
EU - Europa 223.086
NA - Nord America 6.739
AS - Asia 875
AF - Africa 11
SA - Sud America 10
Continente sconosciuto - Info sul continente non disponibili 8
OC - Oceania 2
Totale 230.731
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Nazione #
IT - Italia 220.933
US - Stati Uniti d'America 6.697
UA - Ucraina 759
CN - Cina 695
SE - Svezia 597
DE - Germania 302
FI - Finlandia 200
GB - Regno Unito 180
VN - Vietnam 52
FR - Francia 50
CA - Canada 34
IN - India 34
SG - Singapore 29
HK - Hong Kong 21
RU - Federazione Russa 20
PK - Pakistan 18
BE - Belgio 12
IR - Iran 11
EU - Europa 7
CL - Cile 6
PT - Portogallo 6
ES - Italia 5
MX - Messico 5
EG - Egitto 4
HU - Ungheria 4
CZ - Repubblica Ceca 3
ID - Indonesia 3
IE - Irlanda 3
MA - Marocco 3
PL - Polonia 3
TN - Tunisia 3
TR - Turchia 3
AU - Australia 2
HR - Croazia 2
IL - Israele 2
JP - Giappone 2
NL - Olanda 2
A1 - Anonimo 1
BR - Brasile 1
CH - Svizzera 1
CM - Camerun 1
CO - Colombia 1
CR - Costa Rica 1
DO - Repubblica Dominicana 1
IM - Isola di Man 1
IQ - Iraq 1
KW - Kuwait 1
LA - Repubblica Popolare Democratica del Laos 1
LU - Lussemburgo 1
PA - Panama 1
PE - Perù 1
RO - Romania 1
SI - Slovenia 1
TH - Thailandia 1
TW - Taiwan 1
UY - Uruguay 1
Totale 230.731
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Città #
Cagliari 220.457
Fairfield 860
Woodbridge 665
Chandler 646
Houston 459
Ashburn 431
Nyköping 430
Ann Arbor 392
Jacksonville 390
Wilmington 368
Seattle 362
Dearborn 254
Cambridge 251
Nanjing 136
New York 125
Boardman 118
Beijing 104
Boston 103
Helsinki 87
Shanghai 74
Redwood City 54
Shenyang 52
Dong Ket 49
Guangzhou 49
Nanchang 49
San Diego 41
Hebei 33
Changsha 31
Jiaxing 26
Mountain View 26
Herndon 23
Toronto 23
Verona 23
Milan 21
Norwalk 20
Redmond 20
Hong Kong 18
Jinan 18
Tianjin 17
Los Angeles 16
Atlanta 15
Auburn Hills 15
London 15
Sassari 15
Orange 14
Kunming 13
Brussels 12
Hangzhou 12
Rome 12
Washington 12
Zhengzhou 12
Gujranwala 11
Taizhou 10
Mumbai 9
Olbia 8
Ottawa 8
Phoenix 8
Walnut 8
Hefei 7
Quartu Sant'Elena 7
Quartu Sant'elena 7
Falls Church 6
Indiana 6
Millbury 6
Ningbo 6
Saint Petersburg 6
Cosenza 5
Paris 5
Pune 5
San Francisco 5
Siracusa 5
Yellow Springs 5
Zerfalìu 5
Berlin 4
Borås 4
Chengdu 4
Bultei 3
Chiswick 3
Hanoi 3
Jakarta 3
Kilburn 3
La Jolla 3
Napoli 3
Rabat 3
Singapore 3
Villanovafranca 3
Warsaw 3
Acton 2
Augusta 2
Baotou 2
Barcelona 2
Cairo 2
Calasetta 2
Central 2
Chicago 2
Dolianova 2
Durham 2
Florence 2
Fuzhou 2
Hanover 2
Totale 227.687
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Nome #
Exploring the thiazole scaffold for the identification of new agents for the treatment of fluconazole resistant Candida 4.414
Methoxyflavones from Stachys glutinosa with binding affinity to opioid receptors: in silico, in vitro, and in vivo studies 4.141
(3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro- 1H -indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase 4.131
Design, synthesis, and biological evaluation of 1,3-diarylpropenones as dual inhibitors of HIV-1 reverse transcriptase 4.079
Ribonuclease H/DNA polymerase HIV-1 reverse transcriptase dual inhibitor: mechanistic studies on the allosteric mode of action of isatin-based compound RMNC6 3.964
Isatin thiazoline hybrids as dual inhibitors of HIV-1 reverse transcriptase 3.841
Natural product-inspired esters and amides of ferulic and caffeic acid as dual inhibitors of HIV-1 reverse transcriptase 3.787
3-Acetyl-2,5-diaryl-2,3-dihydro-1,3,4-oxadiazoles: A new scaffold for the selective inhibition of monoamine oxidase B 3.700
New 4-[(3-cyclohexyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzene-1-sulfonamides, synthesis and inhibitory activity toward carbonic anhydrase I, II, IX, XII 3.606
Isatin: a privileged scaffold for the design of carbonic anhydrase inhibitors 3.549
Phenylpropenoids from Bupleurum fruticosum as Anti-Human Rhinovirus Species A Selective Capsid Binders 3.547
Drug design, synthesis, in vitro and in silico evaluation of selective monoaminoxidase B inhibitors based on 3-acetyl-2-dichlorophenyl-5-aryl-2,3-dihydro-1,3,4-oxadiazole chemical scaffold 3.500
N-Alkyl dien- and trienamides from the roots of Otanthus maritimus with binding affinity for opioid and cannabinoid receptors 3.383
A novel series of 3,4-disubstituted dihydropyrazoles: Synthesis and evaluation for MAO enzyme inhibition 3.352
Identification of Myricetin as Ebolavirus VP35-dsRNA interaction inhibitor through a novel fluorescence-based assay 3.218
Quercetin blocks Ebola Virus infection by counteracting the VP24 Interferon inhibitory function 3.217
2-(2-cycloalkylidene hydrazin-1-yl)-4-aryl-1,3-thiazoles: a promising class of antifungal agents 3.164
N-alkylamides from Otanthus maritimus: structure elucidation, binding affinity for cannabinoid receptors and computational study 3.138
Ferulic Acid Esters and Withanolides: in Search of Withania somnifera GABAA Receptor Modulators 3.136
Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach 3.118
Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 Reverse transcriptase-associated RNase H and RDDP functions 3.112
Through scaffold modification to 3,5-diaryl-4,5-dihydroisoxazoles: new potent and selective inhibitors of monoamine oxidase B 3.061
Sennoside A, derived from the traditional chinese medicine plant Rheum L., is a new dual HIV-1 inhibitor effective on HIV-1 replication 3.056
Multi-target activity of Hemidesmus indicus decoction against innovative HIV-1 drug targets and characterization of Lupeol mode of action 2.926
N-Acylbenzenesulfonamide dihydro-1,3,4-oxadiazole hybrids: seeking selectivity toward carbonic anhydrase isoforms 2.915
Studies on Cycloheptathiophene-3-carboxamide Derivatives as Allosteric HIV-1 Ribonuclease H Inhibitors 2.913
Synthesis and biological assessment of novel 2-thiazolylhydrazones and computational analysis of their recognition by monoamine oxidase B 2.909
Synthesis of new 3-aryl-4,5-dihydropyrazole-1-carbothioamide derivatives. An investigation on their ability to inhibit monoamine oxidase 2.822
Targeting tumor associated carbonic anhydrase IX and XII: Highly isozyme selective coumarin and psoralen inhibitors 2.664
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) shed light on the mechanism of action of a new Ribonuclease H/ DNA polymerase RT dual inhibitor 2.659
Investigating the Anticancer Activity of Isatin/Dihydropyrazole Hybrids 2.649
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) enlighten the mechanism of action of a new Ribonuclease H/DNA polymerase RT dual inhibitor 2.619
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Single Site Dual Inhibitors of HIV-1 RT 2.618
Novel natural non-nucleoside inhibitors of HIV-1 reverse transcriptase identified by shape- and structure-based virtual screening techniques 2.598
Coumarins from Magydaris pastinacea as inhibitors of the tumour-associated carbonic anhydrases IX and XII: isolation, biological studies and in silico evaluation 2.581
From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors 2.571
In search of new antitumor agents through the combination of individually active moieties: construction of a [3,5-diaryl-(4,5- dihydropyrazol-1-yl)-4-oxo-1,3-thiazol-5-ylidene]- 1H-indol-2-ones library 2.531
Tuning the Dual Inhibition of Carbonic Anhydrase and Cyclooxygenase by Dihydrothiazole Benzensulfonamides 2.492
MD protocol validation for the study of MAOB-inhibitor complexes 2.449
Synthesis and characterization of new phthalhydrazothiazole derivatives: A preliminary investigation on their activity against hepatocellular carcinoma 2.392
Towards the total block of HIV-1 Reverse Transcriptase: the dual-inhibitors approach 2.387
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Dual Inhibitors of HIV-1 RT. 2.329
Structure-based virtual screening of novel natural alkaloid derivatives as potential binders of h-telo and c-myc DNA G-quadruplex conformations 2.307
Investigation on the mechanism of action of new dual inhibitors of HIV-1 RT 2.289
Exploring new structural features of the 4-[(3-methyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzenesulphonamide scaffold for the inhibition of human carbonic anhydrases 2.270
Molecular Aspects of the RT/drug Interactions. Perspective of Dual Inhibitors 2.244
Chalcones as novel dual inhibitors of HIV-1 reverse transcriptase 2.205
New dual inhibitors of RT associated functions: investigation on their mechanism and mode of action 2.200
Synthesis and biological activity evaluation of new dual-inhibitors of both associated functions of HIV-1 RT 2.189
3-[2-(4-aryl-1,3-thiazol-2-yl)hydrazin-1-ylidene]-1H-indol-2-ones as new potential dual inhibitors of polimerase and ribonuclease HIV-1 RT associated function 2.104
Exploring new scaffolds for the inibition of the Ribonuclease H function of RT HIV-1 2.023
New promising scaffolds for the inhibition of monoamine oxidase B 2.008
Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement 1.976
null 1.949
Design and synthesis of new Isatin derivatives as HIV-1 Reverse Transcriptase associated Ribonuclease H inhibitors twenty-fourth 1.924
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases 1.830
Design, synthesis and biological activity evaluation of c-myc proto-oncogene binders as potential antitumor agents 1.825
Mutagenic study on HIV-1 reverse transcriptase to explore the mechanism of action of HIV-1 reverse transcriptase dual inhibitors 1.778
Targeting HIV-1 RNase H: N'-(2-Hydroxy-benzylidene)-3,4,5-Trihydroxybenzoylhydrazone as Selective Inhibitor Active against NNRTIs-Resistant Variants 1.748
Synthesis and anti-microbial activity evaluation of some new 1-benzoyl-isothiosemicarbazides. 1.730
Isatin derivatives as new scaffolds for HIV-1 reverse transcriptase associated RNase H and RDDP dual inhibitors 1.715
Design of new inhibitors of the HIV-1 Reverse Transcriptase associated Ribonuclease H function: a synthetic approach 1.694
Synthesis, semipreparative HPLC separation, biological evaluation, and 3D-QSAR of hydrazothiazole derivatives as human monoamine oxidase B inhibitors 1.673
Identification of new scaffolds for the inhibition of HIV-1 Reverse Transcriptase associated Ribonuclease H function by means of shape based similarity screening 1.515
null 1.499
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and Ribonuclease H activities effective also on non-nucleoside resistant RTs 1.493
Toward the design of new DNA G-quadruplex ligands through rational analysis of polymorphism and binding data 1.485
SITE DIRECT MUTAGENESIS AND KINETIC STUDIES TO EXPLORE THE MECHANISM OF ACTION OF ISATIN DERIVATIVES AS HIV-1 REVERSE TRANSCRIPTASE DUAL INHIBITORS 1.465
Exploring new scaffolds for the inhibition of the Ribonuclease H function of RT HIV-1 1.418
SYNTHESIS, MOLECULAR MODELLING, INHIBITORY ACTIVITY, AND SELECTIVITY TOWARDS MONOAMINE OXIDASE OF NEW HETEROCYCLIC SCAFFOLDS 1.406
Design, synthesis and biological activity evaluation of new HIV-1 reverse transcriptase dual inhibitors 1.391
From classic to innovative approaches in HIV-1 infection treatment 1.304
Synthesis and biological evaluation of new dual inhibitors of HIV-1 associated functions 1.297
2-methoxynaphthalen thiazole derivate : a new HIV-1 RT Ribonuclease H/DNA polymerase dual inhibitor active on viral replication 1.293
Flavonoids and Acid-Hydrolysis derivatives of Neo-Clerodane diterpenes from Teucrium flavum subsp. glaucum as inhibitors of the HIV-1 reverse transcriptase–associated RNase H function 1.273
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase (RT) -associated DNA polymerase and Ribonuclease H (RNase H) activities effective also on the RNase H activity of non-nucleoside resistant RTs 1.144
Molecular interaction fields in drug discovery: Recent advances and future perspectives 1.143
Shape based computer aided similarity screening: a valid tool in the discovery of new scaffolds for the inhibition of HIV-1 reverse transcriptase associated ribonuclease H function 1.136
9-fluorenones as new scaffolds for G-quadruplex DNA 1.055
Design, synthesis and biological evaluation of new fluorenone derivatives as DNA G-quadruplex binders 968
null 943
An investigation of the biological effect of structural modifications of isothiosemicarbazones and their cyclic analogues 930
Identification of G-quadruplex DNA/RNA binders: Structure-based virtual screening and biophysical characterization 915
A combined shape-, 2D-fingerprint-and pharmacophore-based virtual screening for the identification of dual inhibitors targeting HIV-1 reverse transcriptase. 905
New Dihydrothiazole Benzensulfonamides: Looking for Selectivity toward Carbonic Anhydrase Isoforms I, II, IX, and XII 904
Progettazione e sintesi di 4-(5-ariliden-3-metil-4-ossotiazolidin-2-ilidenamino)benzensulfonamidi e 4-(5-alchiliden-3-metil-4-ossotiazolidin-2-ilidenammino)benzensulfonamidi quali potenziali inibitori selettivi delle ciclossigenasi 2 903
Synthesis, molecular modelling, inhibitory acivity, and selectivity towards monoamine oxidase of new heterocyclic scaffold 885
Computational approaches for discovery and optimization of monoamine oxidase B inhibitors 876
Synthesis and in vitro activity of 2-thiazolylhydrazone derivatives compared with the activity of clotrimazole against clinical isolates of Candida spp 863
GRID-based three-dimensional pharmacophores II: PharmBench, a benchmark data set for evaluating pharmacophore elucidation methods 851
null 818
CoMFA studies of non-covalent monoamine oxidase inhibitors 804
1-benzenesulfonamide-1(H)-pyrazoles and 3-benzenesulfonamide-4-tiazolidinones, two promising scaffolds for the design of cycloxygenase inhibitors 794
The polymorfisms of DNA G-quadruplex investigated by docking experiments with Telomestatin enantiomers 786
2-(2-methyl-2-nitrovinyl)furan but not furvina interfere with staphylococcus aureus agr quorum-sensing system and potentiate the action of fusidic acid against biofilms 784
Sintesi di cicloalchilidenidrazo-4-ariltiazoli ad elevata attività inibitrice selettiva sulla isoforma B delle monoammino ossidasi 770
Combining induced fit docking and molecular dynamics simulations to predict the binding mode of new monoamine oxidase B inhibitors 766
Cynarin blocks Ebola virus replication by counteracting VP35 inhibition of interferon-beta production 752
Tri-substituted thiazolines as promising scaffolds for the design of efficient COX inhibitors 750
Exploring new scaffolds for the dual inhibition of HIV-1 RT polymerase and ribonuclease associated functions 747
Totale 211.950
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Categoria #
all - tutte 259.328
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 259.328
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/20191.628 0 0 0 0 0 0 0 0 0 0 989 639
2019/202041.489 2.104 1.761 362 878 13.376 10.165 5.525 1.281 1.001 1.401 1.337 2.298
2020/202161.923 2.205 2.322 3.322 15.621 11.533 6.418 4.941 3.647 1.731 4.064 4.167 1.952
2021/202212.740 1.525 1.086 646 847 1.061 824 750 630 1.301 1.208 1.398 1.464
2022/202320.237 1.646 2.883 2.600 2.010 1.338 2.081 987 1.596 1.123 1.179 1.621 1.173
2023/202420.288 1.203 580 3.166 2.564 2.398 3.826 2.442 1.555 1.144 1.172 238 0
Totale 231.164