UNICA IRIS Institutional Research Information System

DISTINTO, SIMONA
 Distribuzione geografica
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Continente #
EU - Europa 274.089
NA - Nord America 10.011
AS - Asia 4.599
SA - Sud America 668
AF - Africa 175
OC - Oceania 9
Continente sconosciuto - Info sul continente non disponibili 8
Totale 289.559
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Nazione #
IT - Italia 271.078
US - Stati Uniti d'America 9.867
SG - Singapore 1.755
CN - Cina 1.657
UA - Ucraina 768
SE - Svezia 671
BR - Brasile 506
DE - Germania 428
VN - Vietnam 382
FI - Finlandia 355
GB - Regno Unito 249
FR - Francia 227
HK - Hong Kong 175
IN - India 147
KR - Corea 87
CA - Canada 76
MA - Marocco 71
BD - Bangladesh 65
AR - Argentina 53
AT - Austria 51
NL - Olanda 49
RU - Federazione Russa 48
IQ - Iraq 45
PK - Pakistan 42
JP - Giappone 41
MX - Messico 41
ZA - Sudafrica 39
PL - Polonia 33
TR - Turchia 33
ID - Indonesia 23
SA - Arabia Saudita 22
EC - Ecuador 21
VE - Venezuela 21
CO - Colombia 20
IE - Irlanda 20
ES - Italia 19
BE - Belgio 18
PH - Filippine 16
CL - Cile 15
KE - Kenya 15
EG - Egitto 14
JO - Giordania 14
CZ - Repubblica Ceca 13
TN - Tunisia 13
IR - Iran 12
PY - Paraguay 12
UZ - Uzbekistan 12
NP - Nepal 10
PE - Perù 10
PT - Portogallo 10
LT - Lituania 9
AE - Emirati Arabi Uniti 8
AU - Australia 7
EU - Europa 7
IL - Israele 7
MY - Malesia 7
ET - Etiopia 6
HU - Ungheria 6
KG - Kirghizistan 6
PA - Panama 6
TW - Taiwan 6
CR - Costa Rica 5
RO - Romania 5
UY - Uruguay 5
AL - Albania 4
BO - Bolivia 4
DZ - Algeria 4
GE - Georgia 4
KW - Kuwait 4
AZ - Azerbaigian 3
DO - Repubblica Dominicana 3
GR - Grecia 3
LB - Libano 3
MD - Moldavia 3
NI - Nicaragua 3
BA - Bosnia-Erzegovina 2
BH - Bahrain 2
CH - Svizzera 2
HR - Croazia 2
IS - Islanda 2
JM - Giamaica 2
KH - Cambogia 2
LV - Lettonia 2
MU - Mauritius 2
NG - Nigeria 2
RS - Serbia 2
SI - Slovenia 2
SK - Slovacchia (Repubblica Slovacca) 2
SN - Senegal 2
TH - Thailandia 2
A1 - Anonimo 1
AW - Aruba 1
BB - Barbados 1
BG - Bulgaria 1
BN - Brunei Darussalam 1
BS - Bahamas 1
BW - Botswana 1
BY - Bielorussia 1
CG - Congo 1
CM - Camerun 1
Totale 289.537
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Città #
Cagliari 265.469
Uta 4.995
Singapore 921
Ashburn 882
Fairfield 860
Woodbridge 665
Chandler 646
Dallas 564
San Jose 509
Houston 464
Nyköping 430
Boardman 406
Ann Arbor 392
Jacksonville 391
Seattle 370
Wilmington 369
Beijing 334
Dearborn 254
Cambridge 251
Helsinki 224
Los Angeles 201
New York 166
The Dalles 160
Hong Kong 154
Nanjing 137
Santa Clara 136
Lauterbourg 132
Shanghai 127
Boston 119
Ho Chi Minh City 110
Hefei 102
Council Bluffs 100
Seoul 85
Hanoi 80
Casablanca 64
Buffalo 62
Guangzhou 57
Redwood City 54
Shenyang 53
Munich 52
Dong Ket 49
Nanchang 49
Chicago 47
San Diego 43
São Paulo 42
Amsterdam 39
Orem 38
Verona 36
Vienna 36
Frankfurt am Main 35
Milan 35
Changsha 34
Hebei 33
Redondo Beach 33
Toronto 33
Jiaxing 31
London 31
Tokyo 30
Warsaw 30
Chennai 28
Mountain View 26
Sassari 26
Phoenix 24
Tianjin 24
Herndon 23
Mumbai 22
Johannesburg 21
San Francisco 21
Jinan 20
Norwalk 20
Redmond 20
Atlanta 19
Nuremberg 19
Rio de Janeiro 19
Dublin 18
Salt Lake City 18
Brooklyn 17
Montreal 17
Baghdad 16
Brussels 16
Kunming 16
Washington 16
Auburn Hills 15
Haiphong 15
Hangzhou 15
Zhengzhou 15
Mexico City 14
Nairobi 14
Orange 14
Rome 14
Columbus 13
Tampa 13
Da Nang 12
Tashkent 12
Wuhan 12
Amman 11
Denver 11
Dhaka 11
Gujranwala 11
Lahore 11
Totale 282.950
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Nome #
(3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro- 1H -indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase 14.721
Exploring the thiazole scaffold for the identification of new agents for the treatment of fluconazole resistant Candida 5.057
Methoxyflavones from Stachys glutinosa with binding affinity to opioid receptors: in silico, in vitro, and in vivo studies 4.700
Phenylpropenoids from Bupleurum fruticosum as Anti-Human Rhinovirus Species A Selective Capsid Binders 4.693
Natural product-inspired esters and amides of ferulic and caffeic acid as dual inhibitors of HIV-1 reverse transcriptase 4.679
Design, synthesis, and biological evaluation of 1,3-diarylpropenones as dual inhibitors of HIV-1 reverse transcriptase 4.522
Quercetin blocks Ebola Virus infection by counteracting the VP24 Interferon inhibitory function 4.465
Isatin: a privileged scaffold for the design of carbonic anhydrase inhibitors 4.441
2-(2-cycloalkylidene hydrazin-1-yl)-4-aryl-1,3-thiazoles: a promising class of antifungal agents 4.406
Ribonuclease H/DNA polymerase HIV-1 reverse transcriptase dual inhibitor: mechanistic studies on the allosteric mode of action of isatin-based compound RMNC6 4.328
3-Acetyl-2,5-diaryl-2,3-dihydro-1,3,4-oxadiazoles: A new scaffold for the selective inhibition of monoamine oxidase B 4.316
Isatin thiazoline hybrids as dual inhibitors of HIV-1 reverse transcriptase 4.183
N-Alkyl dien- and trienamides from the roots of Otanthus maritimus with binding affinity for opioid and cannabinoid receptors 3.942
New 4-[(3-cyclohexyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzene-1-sulfonamides, synthesis and inhibitory activity toward carbonic anhydrase I, II, IX, XII 3.934
Drug design, synthesis, in vitro and in silico evaluation of selective monoaminoxidase B inhibitors based on 3-acetyl-2-dichlorophenyl-5-aryl-2,3-dihydro-1,3,4-oxadiazole chemical scaffold 3.780
A novel series of 3,4-disubstituted dihydropyrazoles: Synthesis and evaluation for MAO enzyme inhibition 3.776
Identification of Myricetin as Ebolavirus VP35-dsRNA interaction inhibitor through a novel fluorescence-based assay 3.744
Ferulic Acid Esters and Withanolides: in Search of Withania somnifera GABAA Receptor Modulators 3.607
Targeting tumor associated carbonic anhydrase IX and XII: Highly isozyme selective coumarin and psoralen inhibitors 3.539
Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 Reverse transcriptase-associated RNase H and RDDP functions 3.514
Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach 3.483
Sennoside A, derived from the traditional chinese medicine plant Rheum L., is a new dual HIV-1 inhibitor effective on HIV-1 replication 3.432
Coumarins from Magydaris pastinacea as inhibitors of the tumour-associated carbonic anhydrases IX and XII: isolation, biological studies and in silico evaluation 3.423
N-alkylamides from Otanthus maritimus: structure elucidation, binding affinity for cannabinoid receptors and computational study 3.419
Through scaffold modification to 3,5-diaryl-4,5-dihydroisoxazoles: new potent and selective inhibitors of monoamine oxidase B 3.370
Studies on Cycloheptathiophene-3-carboxamide Derivatives as Allosteric HIV-1 Ribonuclease H Inhibitors 3.308
Molecular Aspects of the RT/drug Interactions. Perspective of Dual Inhibitors 3.306
Multi-target activity of Hemidesmus indicus decoction against innovative HIV-1 drug targets and characterization of Lupeol mode of action 3.295
Synthesis and biological assessment of novel 2-thiazolylhydrazones and computational analysis of their recognition by monoamine oxidase B 3.282
Synthesis of new 3-aryl-4,5-dihydropyrazole-1-carbothioamide derivatives. An investigation on their ability to inhibit monoamine oxidase 3.216
N-Acylbenzenesulfonamide dihydro-1,3,4-oxadiazole hybrids: seeking selectivity toward carbonic anhydrase isoforms 3.200
Novel natural non-nucleoside inhibitors of HIV-1 reverse transcriptase identified by shape- and structure-based virtual screening techniques 3.086
Investigating the Anticancer Activity of Isatin/Dihydropyrazole Hybrids 3.037
Tuning the Dual Inhibition of Carbonic Anhydrase and Cyclooxygenase by Dihydrothiazole Benzensulfonamides 3.036
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Dual Inhibitors of HIV-1 RT. 3.033
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) enlighten the mechanism of action of a new Ribonuclease H/DNA polymerase RT dual inhibitor 2.969
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Single Site Dual Inhibitors of HIV-1 RT 2.918
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) shed light on the mechanism of action of a new Ribonuclease H/ DNA polymerase RT dual inhibitor 2.909
From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors 2.858
MD protocol validation for the study of MAOB-inhibitor complexes 2.774
Mutagenic study on HIV-1 reverse transcriptase to explore the mechanism of action of HIV-1 reverse transcriptase dual inhibitors 2.769
In search of new antitumor agents through the combination of individually active moieties: construction of a [3,5-diaryl-(4,5- dihydropyrazol-1-yl)-4-oxo-1,3-thiazol-5-ylidene]- 1H-indol-2-ones library 2.745
Structure-based virtual screening of novel natural alkaloid derivatives as potential binders of h-telo and c-myc DNA G-quadruplex conformations 2.639
Synthesis and biological activity evaluation of new dual-inhibitors of both associated functions of HIV-1 RT 2.629
3-[2-(4-aryl-1,3-thiazol-2-yl)hydrazin-1-ylidene]-1H-indol-2-ones as new potential dual inhibitors of polimerase and ribonuclease HIV-1 RT associated function 2.611
Towards the total block of HIV-1 Reverse Transcriptase: the dual-inhibitors approach 2.607
Exploring new structural features of the 4-[(3-methyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzenesulphonamide scaffold for the inhibition of human carbonic anhydrases 2.548
Investigation on the mechanism of action of new dual inhibitors of HIV-1 RT 2.545
Synthesis and characterization of new phthalhydrazothiazole derivatives: A preliminary investigation on their activity against hepatocellular carcinoma 2.533
Chalcones as novel dual inhibitors of HIV-1 reverse transcriptase 2.456
New dual inhibitors of RT associated functions: investigation on their mechanism and mode of action 2.446
New promising scaffolds for the inhibition of monoamine oxidase B 2.304
Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement 2.295
Exploring new scaffolds for the inibition of the Ribonuclease H function of RT HIV-1 2.259
Design and synthesis of new Isatin derivatives as HIV-1 Reverse Transcriptase associated Ribonuclease H inhibitors twenty-fourth 2.148
Isatin derivatives as new scaffolds for HIV-1 reverse transcriptase associated RNase H and RDDP dual inhibitors 2.136
Targeting HIV-1 RNase H: N'-(2-Hydroxy-benzylidene)-3,4,5-Trihydroxybenzoylhydrazone as Selective Inhibitor Active against NNRTIs-Resistant Variants 2.107
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases 2.101
Design, synthesis and biological activity evaluation of c-myc proto-oncogene binders as potential antitumor agents 2.072
Design, synthesis and biological activity evaluation of new HIV-1 reverse transcriptase dual inhibitors 1.967
null 1.949
Synthesis and anti-microbial activity evaluation of some new 1-benzoyl-isothiosemicarbazides. 1.930
Design of new inhibitors of the HIV-1 Reverse Transcriptase associated Ribonuclease H function: a synthetic approach 1.880
Synthesis, semipreparative HPLC separation, biological evaluation, and 3D-QSAR of hydrazothiazole derivatives as human monoamine oxidase B inhibitors 1.864
Identification of new scaffolds for the inhibition of HIV-1 Reverse Transcriptase associated Ribonuclease H function by means of shape based similarity screening 1.809
SITE DIRECT MUTAGENESIS AND KINETIC STUDIES TO EXPLORE THE MECHANISM OF ACTION OF ISATIN DERIVATIVES AS HIV-1 REVERSE TRANSCRIPTASE DUAL INHIBITORS 1.795
New Dihydrothiazole Benzensulfonamides: Looking for Selectivity toward Carbonic Anhydrase Isoforms I, II, IX, and XII 1.736
Toward the design of new DNA G-quadruplex ligands through rational analysis of polymorphism and binding data 1.719
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and Ribonuclease H activities effective also on non-nucleoside resistant RTs 1.707
Exploring new scaffolds for the inhibition of the Ribonuclease H function of RT HIV-1 1.705
SYNTHESIS, MOLECULAR MODELLING, INHIBITORY ACTIVITY, AND SELECTIVITY TOWARDS MONOAMINE OXIDASE OF NEW HETEROCYCLIC SCAFFOLDS 1.684
Flavonoids and Acid-Hydrolysis derivatives of Neo-Clerodane diterpenes from Teucrium flavum subsp. glaucum as inhibitors of the HIV-1 reverse transcriptase–associated RNase H function 1.628
Synthesis and biological evaluation of new dual inhibitors of HIV-1 associated functions 1.611
From classic to innovative approaches in HIV-1 infection treatment 1.556
2-methoxynaphthalen thiazole derivate : a new HIV-1 RT Ribonuclease H/DNA polymerase dual inhibitor active on viral replication 1.518
null 1.499
Shape based computer aided similarity screening: a valid tool in the discovery of new scaffolds for the inhibition of HIV-1 reverse transcriptase associated ribonuclease H function 1.429
Cynarin blocks Ebola virus replication by counteracting VP35 inhibition of interferon-beta production 1.425
Molecular interaction fields in drug discovery: Recent advances and future perspectives 1.423
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase (RT) -associated DNA polymerase and Ribonuclease H (RNase H) activities effective also on the RNase H activity of non-nucleoside resistant RTs 1.374
Identification of G-quadruplex DNA/RNA binders: Structure-based virtual screening and biophysical characterization 1.330
2-(2-methyl-2-nitrovinyl)furan but not furvina interfere with staphylococcus aureus agr quorum-sensing system and potentiate the action of fusidic acid against biofilms 1.315
9-fluorenones as new scaffolds for G-quadruplex DNA 1.238
Exploring new scaffolds for the dual inhibition of HIV-1 RT polymerase and ribonuclease associated functions 1.198
A combined shape-, 2D-fingerprint-and pharmacophore-based virtual screening for the identification of dual inhibitors targeting HIV-1 reverse transcriptase. 1.179
An investigation of the biological effect of structural modifications of isothiosemicarbazones and their cyclic analogues 1.130
Design, synthesis and biological evaluation of new fluorenone derivatives as DNA G-quadruplex binders 1.125
Synthesis, molecular modelling, inhibitory acivity, and selectivity towards monoamine oxidase of new heterocyclic scaffold 1.112
GRID-based three-dimensional pharmacophores II: PharmBench, a benchmark data set for evaluating pharmacophore elucidation methods 1.111
Synthesis and in vitro activity of 2-thiazolylhydrazone derivatives compared with the activity of clotrimazole against clinical isolates of Candida spp 1.071
Progettazione e sintesi di 4-(5-ariliden-3-metil-4-ossotiazolidin-2-ilidenamino)benzensulfonamidi e 4-(5-alchiliden-3-metil-4-ossotiazolidin-2-ilidenammino)benzensulfonamidi quali potenziali inibitori selettivi delle ciclossigenasi 2 1.043
The polymorfisms of DNA G-quadruplex investigated by docking experiments with Telomestatin enantiomers 1.030
Computational approaches for discovery and optimization of monoamine oxidase B inhibitors 1.029
The polymorphisms of DNA G-quadruplex investigated by docking experiments with telomestatin enantiomers 981
1-benzenesulfonamide-1(H)-pyrazoles and 3-benzenesulfonamide-4-tiazolidinones, two promising scaffolds for the design of cycloxygenase inhibitors 970
null 943
CoMFA studies of non-covalent monoamine oxidase inhibitors 941
Tri-substituted thiazolines as promising scaffolds for the design of efficient COX inhibitors 938
The discovery of new G-quadruplex binders through a structure-based virtual screening approach 928
Combining induced fit docking and molecular dynamics simulations to predict the binding mode of new monoamine oxidase B inhibitors 924
Totale 260.395
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Categoria #
all - tutte 340.318
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 340.318
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202110.183 0 0 0 0 0 0 0 0 0 4.064 4.167 1.952
2021/202212.740 1.525 1.086 646 847 1.061 824 750 630 1.301 1.208 1.398 1.464
2022/202320.237 1.646 2.883 2.600 2.010 1.338 2.081 987 1.596 1.123 1.179 1.621 1.173
2023/202423.399 1.203 580 3.166 2.564 2.398 3.826 2.442 1.555 1.144 1.172 1.570 1.779
2024/202545.702 13.991 12.597 6.370 4.118 1.941 2.531 2.289 212 484 330 378 461
2025/202610.065 716 434 1.240 955 822 651 1.419 1.265 918 1.645 0 0
Totale 290.042