UNICA IRIS Institutional Research Information System

DISTINTO, SIMONA
 Distribuzione geografica
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Continente #
EU - Europa 274.771
NA - Nord America 10.528
AS - Asia 4.658
SA - Sud America 669
AF - Africa 177
OC - Oceania 9
Continente sconosciuto - Info sul continente non disponibili 8
Totale 290.820
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Nazione #
IT - Italia 271.756
US - Stati Uniti d'America 10.368
SG - Singapore 1.759
CN - Cina 1.668
UA - Ucraina 768
SE - Svezia 673
BR - Brasile 507
DE - Germania 428
VN - Vietnam 383
FI - Finlandia 355
GB - Regno Unito 249
FR - Francia 227
HK - Hong Kong 181
IN - India 147
BD - Bangladesh 102
KR - Corea 87
CA - Canada 83
MA - Marocco 71
AR - Argentina 53
AT - Austria 51
NL - Olanda 50
RU - Federazione Russa 48
IQ - Iraq 45
MX - Messico 43
PK - Pakistan 42
JP - Giappone 41
ZA - Sudafrica 39
PL - Polonia 33
TR - Turchia 33
ID - Indonesia 23
SA - Arabia Saudita 22
EC - Ecuador 21
VE - Venezuela 21
CO - Colombia 20
IE - Irlanda 20
ES - Italia 19
BE - Belgio 18
PH - Filippine 16
CL - Cile 15
EG - Egitto 15
KE - Kenya 15
JO - Giordania 14
CZ - Repubblica Ceca 13
TN - Tunisia 13
IR - Iran 12
PY - Paraguay 12
UZ - Uzbekistan 12
NP - Nepal 10
PE - Perù 10
PT - Portogallo 10
LT - Lituania 9
AE - Emirati Arabi Uniti 8
AU - Australia 7
EU - Europa 7
IL - Israele 7
MY - Malesia 7
CR - Costa Rica 6
ET - Etiopia 6
HU - Ungheria 6
JM - Giamaica 6
KG - Kirghizistan 6
PA - Panama 6
TW - Taiwan 6
RO - Romania 5
UY - Uruguay 5
AL - Albania 4
BO - Bolivia 4
DZ - Algeria 4
GE - Georgia 4
KW - Kuwait 4
MD - Moldavia 4
AZ - Azerbaigian 3
DO - Repubblica Dominicana 3
GR - Grecia 3
LB - Libano 3
NI - Nicaragua 3
BA - Bosnia-Erzegovina 2
BH - Bahrain 2
BS - Bahamas 2
CH - Svizzera 2
GT - Guatemala 2
HR - Croazia 2
IS - Islanda 2
KH - Cambogia 2
LV - Lettonia 2
MU - Mauritius 2
NG - Nigeria 2
RS - Serbia 2
SI - Slovenia 2
SK - Slovacchia (Repubblica Slovacca) 2
SN - Senegal 2
TH - Thailandia 2
A1 - Anonimo 1
AW - Aruba 1
BB - Barbados 1
BG - Bulgaria 1
BN - Brunei Darussalam 1
BW - Botswana 1
BY - Bielorussia 1
CG - Congo 1
Totale 290.797
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Città #
Cagliari 266.119
Uta 4.995
Singapore 923
Ashburn 905
Fairfield 860
Woodbridge 666
Chandler 646
San Jose 616
Dallas 571
Houston 468
Boardman 455
Nyköping 430
Jacksonville 394
Ann Arbor 392
Seattle 371
Wilmington 370
Beijing 339
Dearborn 254
Cambridge 251
Helsinki 224
Los Angeles 209
New York 177
Hong Kong 160
The Dalles 160
Santa Clara 145
Nanjing 137
Lauterbourg 132
Council Bluffs 128
Shanghai 127
Boston 120
Ho Chi Minh City 111
Hefei 102
Seoul 85
Hanoi 80
Buffalo 68
Casablanca 64
Guangzhou 57
Redwood City 54
Shenyang 53
Munich 52
Chicago 51
Dong Ket 49
Nanchang 49
Orem 44
San Diego 44
São Paulo 42
Amsterdam 39
Milan 38
Verona 36
Vienna 36
Frankfurt am Main 35
Changsha 34
Hebei 33
Redondo Beach 33
Toronto 33
Jiaxing 31
London 31
Tokyo 30
Warsaw 30
Chennai 28
Mountain View 26
Sassari 26
Atlanta 24
Phoenix 24
Tianjin 24
Herndon 23
Brooklyn 22
Mumbai 22
Johannesburg 21
San Francisco 21
Jinan 20
Norwalk 20
Redmond 20
Montreal 19
Nuremberg 19
Rio de Janeiro 19
Rome 19
Dublin 18
Salt Lake City 18
Washington 17
Baghdad 16
Brussels 16
Hangzhou 16
Kunming 16
Mexico City 16
Auburn Hills 15
Haiphong 15
Zhengzhou 15
Nairobi 14
Orange 14
Tampa 14
Columbus 13
Da Nang 12
Tashkent 12
Wuhan 12
Amman 11
Denver 11
Dhaka 11
Gujranwala 11
Lahore 11
Totale 283.909
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Nome #
(3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro- 1H -indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase 14.730
Exploring the thiazole scaffold for the identification of new agents for the treatment of fluconazole resistant Candida 5.066
Methoxyflavones from Stachys glutinosa with binding affinity to opioid receptors: in silico, in vitro, and in vivo studies 4.710
Phenylpropenoids from Bupleurum fruticosum as Anti-Human Rhinovirus Species A Selective Capsid Binders 4.704
Natural product-inspired esters and amides of ferulic and caffeic acid as dual inhibitors of HIV-1 reverse transcriptase 4.691
Design, synthesis, and biological evaluation of 1,3-diarylpropenones as dual inhibitors of HIV-1 reverse transcriptase 4.533
Quercetin blocks Ebola Virus infection by counteracting the VP24 Interferon inhibitory function 4.482
Isatin: a privileged scaffold for the design of carbonic anhydrase inhibitors 4.447
2-(2-cycloalkylidene hydrazin-1-yl)-4-aryl-1,3-thiazoles: a promising class of antifungal agents 4.418
Ribonuclease H/DNA polymerase HIV-1 reverse transcriptase dual inhibitor: mechanistic studies on the allosteric mode of action of isatin-based compound RMNC6 4.332
3-Acetyl-2,5-diaryl-2,3-dihydro-1,3,4-oxadiazoles: A new scaffold for the selective inhibition of monoamine oxidase B 4.325
Isatin thiazoline hybrids as dual inhibitors of HIV-1 reverse transcriptase 4.192
N-Alkyl dien- and trienamides from the roots of Otanthus maritimus with binding affinity for opioid and cannabinoid receptors 3.949
New 4-[(3-cyclohexyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzene-1-sulfonamides, synthesis and inhibitory activity toward carbonic anhydrase I, II, IX, XII 3.946
Drug design, synthesis, in vitro and in silico evaluation of selective monoaminoxidase B inhibitors based on 3-acetyl-2-dichlorophenyl-5-aryl-2,3-dihydro-1,3,4-oxadiazole chemical scaffold 3.786
A novel series of 3,4-disubstituted dihydropyrazoles: Synthesis and evaluation for MAO enzyme inhibition 3.782
Identification of Myricetin as Ebolavirus VP35-dsRNA interaction inhibitor through a novel fluorescence-based assay 3.757
Ferulic Acid Esters and Withanolides: in Search of Withania somnifera GABAA Receptor Modulators 3.615
Targeting tumor associated carbonic anhydrase IX and XII: Highly isozyme selective coumarin and psoralen inhibitors 3.544
Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 Reverse transcriptase-associated RNase H and RDDP functions 3.519
Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach 3.492
Sennoside A, derived from the traditional chinese medicine plant Rheum L., is a new dual HIV-1 inhibitor effective on HIV-1 replication 3.435
N-alkylamides from Otanthus maritimus: structure elucidation, binding affinity for cannabinoid receptors and computational study 3.430
Coumarins from Magydaris pastinacea as inhibitors of the tumour-associated carbonic anhydrases IX and XII: isolation, biological studies and in silico evaluation 3.430
Through scaffold modification to 3,5-diaryl-4,5-dihydroisoxazoles: new potent and selective inhibitors of monoamine oxidase B 3.380
Molecular Aspects of the RT/drug Interactions. Perspective of Dual Inhibitors 3.316
Studies on Cycloheptathiophene-3-carboxamide Derivatives as Allosteric HIV-1 Ribonuclease H Inhibitors 3.313
Multi-target activity of Hemidesmus indicus decoction against innovative HIV-1 drug targets and characterization of Lupeol mode of action 3.300
Synthesis and biological assessment of novel 2-thiazolylhydrazones and computational analysis of their recognition by monoamine oxidase B 3.293
Synthesis of new 3-aryl-4,5-dihydropyrazole-1-carbothioamide derivatives. An investigation on their ability to inhibit monoamine oxidase 3.226
N-Acylbenzenesulfonamide dihydro-1,3,4-oxadiazole hybrids: seeking selectivity toward carbonic anhydrase isoforms 3.211
Novel natural non-nucleoside inhibitors of HIV-1 reverse transcriptase identified by shape- and structure-based virtual screening techniques 3.102
Tuning the Dual Inhibition of Carbonic Anhydrase and Cyclooxygenase by Dihydrothiazole Benzensulfonamides 3.049
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Dual Inhibitors of HIV-1 RT. 3.043
Investigating the Anticancer Activity of Isatin/Dihydropyrazole Hybrids 3.041
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) enlighten the mechanism of action of a new Ribonuclease H/DNA polymerase RT dual inhibitor 2.981
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Single Site Dual Inhibitors of HIV-1 RT 2.933
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) shed light on the mechanism of action of a new Ribonuclease H/ DNA polymerase RT dual inhibitor 2.923
From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors 2.867
MD protocol validation for the study of MAOB-inhibitor complexes 2.788
Mutagenic study on HIV-1 reverse transcriptase to explore the mechanism of action of HIV-1 reverse transcriptase dual inhibitors 2.776
In search of new antitumor agents through the combination of individually active moieties: construction of a [3,5-diaryl-(4,5- dihydropyrazol-1-yl)-4-oxo-1,3-thiazol-5-ylidene]- 1H-indol-2-ones library 2.754
Synthesis and biological activity evaluation of new dual-inhibitors of both associated functions of HIV-1 RT 2.659
Structure-based virtual screening of novel natural alkaloid derivatives as potential binders of h-telo and c-myc DNA G-quadruplex conformations 2.654
3-[2-(4-aryl-1,3-thiazol-2-yl)hydrazin-1-ylidene]-1H-indol-2-ones as new potential dual inhibitors of polimerase and ribonuclease HIV-1 RT associated function 2.621
Towards the total block of HIV-1 Reverse Transcriptase: the dual-inhibitors approach 2.614
Investigation on the mechanism of action of new dual inhibitors of HIV-1 RT 2.554
Exploring new structural features of the 4-[(3-methyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzenesulphonamide scaffold for the inhibition of human carbonic anhydrases 2.552
Synthesis and characterization of new phthalhydrazothiazole derivatives: A preliminary investigation on their activity against hepatocellular carcinoma 2.542
Chalcones as novel dual inhibitors of HIV-1 reverse transcriptase 2.465
New dual inhibitors of RT associated functions: investigation on their mechanism and mode of action 2.458
New promising scaffolds for the inhibition of monoamine oxidase B 2.311
Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement 2.300
Exploring new scaffolds for the inibition of the Ribonuclease H function of RT HIV-1 2.273
Design and synthesis of new Isatin derivatives as HIV-1 Reverse Transcriptase associated Ribonuclease H inhibitors twenty-fourth 2.157
Isatin derivatives as new scaffolds for HIV-1 reverse transcriptase associated RNase H and RDDP dual inhibitors 2.151
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases 2.113
Targeting HIV-1 RNase H: N'-(2-Hydroxy-benzylidene)-3,4,5-Trihydroxybenzoylhydrazone as Selective Inhibitor Active against NNRTIs-Resistant Variants 2.112
Design, synthesis and biological activity evaluation of c-myc proto-oncogene binders as potential antitumor agents 2.082
Design, synthesis and biological activity evaluation of new HIV-1 reverse transcriptase dual inhibitors 1.979
null 1.949
Synthesis and anti-microbial activity evaluation of some new 1-benzoyl-isothiosemicarbazides. 1.939
Design of new inhibitors of the HIV-1 Reverse Transcriptase associated Ribonuclease H function: a synthetic approach 1.889
Synthesis, semipreparative HPLC separation, biological evaluation, and 3D-QSAR of hydrazothiazole derivatives as human monoamine oxidase B inhibitors 1.871
Identification of new scaffolds for the inhibition of HIV-1 Reverse Transcriptase associated Ribonuclease H function by means of shape based similarity screening 1.817
SITE DIRECT MUTAGENESIS AND KINETIC STUDIES TO EXPLORE THE MECHANISM OF ACTION OF ISATIN DERIVATIVES AS HIV-1 REVERSE TRANSCRIPTASE DUAL INHIBITORS 1.803
New Dihydrothiazole Benzensulfonamides: Looking for Selectivity toward Carbonic Anhydrase Isoforms I, II, IX, and XII 1.741
Toward the design of new DNA G-quadruplex ligands through rational analysis of polymorphism and binding data 1.723
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and Ribonuclease H activities effective also on non-nucleoside resistant RTs 1.719
Exploring new scaffolds for the inhibition of the Ribonuclease H function of RT HIV-1 1.711
SYNTHESIS, MOLECULAR MODELLING, INHIBITORY ACTIVITY, AND SELECTIVITY TOWARDS MONOAMINE OXIDASE OF NEW HETEROCYCLIC SCAFFOLDS 1.690
Flavonoids and Acid-Hydrolysis derivatives of Neo-Clerodane diterpenes from Teucrium flavum subsp. glaucum as inhibitors of the HIV-1 reverse transcriptase–associated RNase H function 1.638
Synthesis and biological evaluation of new dual inhibitors of HIV-1 associated functions 1.614
From classic to innovative approaches in HIV-1 infection treatment 1.566
2-methoxynaphthalen thiazole derivate : a new HIV-1 RT Ribonuclease H/DNA polymerase dual inhibitor active on viral replication 1.535
null 1.499
Cynarin blocks Ebola virus replication by counteracting VP35 inhibition of interferon-beta production 1.436
Shape based computer aided similarity screening: a valid tool in the discovery of new scaffolds for the inhibition of HIV-1 reverse transcriptase associated ribonuclease H function 1.435
Molecular interaction fields in drug discovery: Recent advances and future perspectives 1.429
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase (RT) -associated DNA polymerase and Ribonuclease H (RNase H) activities effective also on the RNase H activity of non-nucleoside resistant RTs 1.388
Identification of G-quadruplex DNA/RNA binders: Structure-based virtual screening and biophysical characterization 1.337
2-(2-methyl-2-nitrovinyl)furan but not furvina interfere with staphylococcus aureus agr quorum-sensing system and potentiate the action of fusidic acid against biofilms 1.325
9-fluorenones as new scaffolds for G-quadruplex DNA 1.245
Exploring new scaffolds for the dual inhibition of HIV-1 RT polymerase and ribonuclease associated functions 1.208
A combined shape-, 2D-fingerprint-and pharmacophore-based virtual screening for the identification of dual inhibitors targeting HIV-1 reverse transcriptase. 1.186
Design, synthesis and biological evaluation of new fluorenone derivatives as DNA G-quadruplex binders 1.137
An investigation of the biological effect of structural modifications of isothiosemicarbazones and their cyclic analogues 1.135
Synthesis, molecular modelling, inhibitory acivity, and selectivity towards monoamine oxidase of new heterocyclic scaffold 1.117
GRID-based three-dimensional pharmacophores II: PharmBench, a benchmark data set for evaluating pharmacophore elucidation methods 1.113
Synthesis and in vitro activity of 2-thiazolylhydrazone derivatives compared with the activity of clotrimazole against clinical isolates of Candida spp 1.078
Progettazione e sintesi di 4-(5-ariliden-3-metil-4-ossotiazolidin-2-ilidenamino)benzensulfonamidi e 4-(5-alchiliden-3-metil-4-ossotiazolidin-2-ilidenammino)benzensulfonamidi quali potenziali inibitori selettivi delle ciclossigenasi 2 1.048
Computational approaches for discovery and optimization of monoamine oxidase B inhibitors 1.041
The polymorfisms of DNA G-quadruplex investigated by docking experiments with Telomestatin enantiomers 1.035
The polymorphisms of DNA G-quadruplex investigated by docking experiments with telomestatin enantiomers 983
1-benzenesulfonamide-1(H)-pyrazoles and 3-benzenesulfonamide-4-tiazolidinones, two promising scaffolds for the design of cycloxygenase inhibitors 976
CoMFA studies of non-covalent monoamine oxidase inhibitors 946
Tri-substituted thiazolines as promising scaffolds for the design of efficient COX inhibitors 944
null 943
The discovery of new G-quadruplex binders through a structure-based virtual screening approach 933
Combining induced fit docking and molecular dynamics simulations to predict the binding mode of new monoamine oxidase B inhibitors 930
Totale 261.260
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Categoria #
all - tutte 344.368
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 344.368
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.952 0 0 0 0 0 0 0 0 0 0 0 1.952
2021/202212.740 1.525 1.086 646 847 1.061 824 750 630 1.301 1.208 1.398 1.464
2022/202320.237 1.646 2.883 2.600 2.010 1.338 2.081 987 1.596 1.123 1.179 1.621 1.173
2023/202423.399 1.203 580 3.166 2.564 2.398 3.826 2.442 1.555 1.144 1.172 1.570 1.779
2024/202545.702 13.991 12.597 6.370 4.118 1.941 2.531 2.289 212 484 330 378 461
2025/202611.327 716 434 1.240 955 822 651 1.419 1.265 918 1.760 655 492
Totale 291.304