UNICA IRIS Institutional Research Information System

Tripartite efflux pumps of the RND superfamily: what did we learn from computational studies?

Bacterial resistance to antibiotics has been long recognized as a priority to address for human health. Among all micro-organisms, the so-called multi -drug resistant (MDR) bacteria, which are resistant to most, if not all drugs in our current arsenal, are particularly worrisome. The World Health Organization has prioritized the ESKAPE (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa and Enterobacter species) pathogens, which...

A Cognitive Social IoT Approach for Smart Energy Management in a Real Environment

Energy usage inside buildings is a critical problem, especially considering high loads such as Heating, Ventilation and Air Conditioning (HVAC) systems: around 50% of the buildings’ energy demand resides in HVAC usage which causes a significant waste of energy resources due to improper uses. Usage awareness and efficient management have the potential to reduce related costs. However, strict saving policies may contrast with users’ comfort. In this sense, this paper proposes a multi-user multi...

Stressing Leadership, Spirituality and Legacy. A Purpose-Driven Approach to Sustainable Business Longevity

This study attempts to bring out not only the notion of business longevity in terms of its temporal dimension but the impact it leaves to every stakeholder- to every person that continually builds the company and for those for which the company has been created. One of Kurt Lewin's most famous aphorisms is “there is nothing so practical as a good theory”. But that was only half of his message, this study also supports the other part, that “nothing contributes more to good theory than practic...

Alberto Laiseca, elucubrazioni al margine del caos